| mTOR controls mitochondrial dynamics and cell survival via MTFP1 M Morita, J Prudent, K Basu, V Goyon, S Katsumura, L Hulea, D Pearl, ... Molecular cell 67 (6), 922-935. e5, 2017 | 339 | 2017 |
| Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by tristetraprolin MR Fabian, F Frank, C Rouya, N Siddiqui, WS Lai, A Karetnikov, ... Nature structural & molecular biology 20 (6), 735-739, 2013 | 297 | 2013 |
| Signalling to eIF4E in cancer N Siddiqui, N Sonenberg Biochemical Society Transactions 43 (5), 763-772, 2015 | 261 | 2015 |
| A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development M Morita, LW Ler, MR Fabian, N Siddiqui, M Mullin, VC Henderson, ... Molecular and cellular biology, 2012 | 226 | 2012 |
| eIF4E/4E-BP ratio predicts the efficacy of mTOR targeted therapies T Alain, M Morita, BD Fonseca, A Yanagiya, N Siddiqui, M Bhat, D Zammit, ... Cancer research 72 (24), 6468-6476, 2012 | 196 | 2012 |
| Molecular dissection of the eukaryotic initiation factor 4E (eIF4E) export‐competent RNP I Topisirovic, N Siddiqui, VL Lapointe, M Trost, P Thibault, C Bangeranye, ... The EMBO journal 28 (8), 1087-1098, 2009 | 177 | 2009 |
| Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1 C Rouya, N Siddiqui, M Morita, TF Duchaine, MR Fabian, N Sonenberg Rna 20 (9), 1398-1409, 2014 | 171 | 2014 |
| Structural basis of ligand recognition by PABC, a highly specific peptide‐binding domain found in poly (A)‐binding protein and a HECT ubiquitin ligase G Kozlov, G De Crescenzo, NS Lim, N Siddiqui, D Fantus, A Kahvejian, ... The EMBO journal 23 (2), 272-281, 2004 | 143 | 2004 |
| mRNA export and cancer N Siddiqui, KLB Borden Wiley Interdisciplinary Reviews: RNA 3 (1), 13-25, 2012 | 141 | 2012 |
| Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer I Topisirovic, N Siddiqui, S Orolicki, LA Skrabanek, M Tremblay, T Hoang, ... Molecular and cellular biology, 2009 | 120 | 2009 |
| Cap‐free structure of eIF4E suggests a basis for conformational regulation by its ligands L Volpon, MJ Osborne, I Topisirovic, N Siddiqui, KLB Borden The EMBO journal 25 (21), 5138-5149, 2006 | 118 | 2006 |
| Poly (A) nuclease interacts with the C-terminal domain of polyadenylate-binding protein domain from poly (A)-binding protein N Siddiqui, DA Mangus, TC Chang, JM Palermino, AB Shyu, K Gehring Journal of Biological Chemistry 282 (34), 25067-25075, 2007 | 114 | 2007 |
| Comparative peptide binding studies of the PABC domains from the ubiquitin-protein isopeptide ligase HYD and poly (A)-binding protein: implications for HYD function NS Lim, G Kozlov, TC Chang, O Groover, N Siddiqui, L Volpon, ... Journal of Biological Chemistry 281 (20), 14376-14382, 2006 | 74 | 2006 |
| Structural insights into the allosteric effects of 4EBP1 on the eukaryotic translation initiation factor eIF4E N Siddiqui, W Tempel, L Nedyalkova, L Volpon, AK Wernimont, ... Journal of molecular biology 415 (5), 781-792, 2012 | 73 | 2012 |
| Solution structure of the orphan pabc domain fromsaccharomyces cerevisiae poly (a)-binding protein G Kozlov, N Siddiqui, S Coillet-Matillon, JF Trempe, I Ekiel, T Sprules, ... Journal of Biological Chemistry 277 (25), 22822-22828, 2002 | 56 | 2002 |
| Dynamic and selective DNA-binding activity of Smc5, a core component of the Smc5-Smc6 complex MA Roy, N Siddiqui, D D'Amours Cell Cycle 10 (4), 690-700, 2011 | 54 | 2011 |
| Structure of the archaeal translation initiation factor aIF2β from Methanobacterium thermoautotrophicum: Implications for translation initiation P Gutiérrez, MJ Osborne, N Siddiqui, JF Trempe, C Arrowsmith, K Gehring Protein Science 13 (3), 659-667, 2004 | 45 | 2004 |
| Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure S Katsumura, N Siddiqui, MR Goldsmith, JH Cheah, T Fujikawa, ... Cell metabolism 34 (4), 564-580. e8, 2022 | 40 | 2022 |
| Proposing a mechanism of action for ataluren N Siddiqui, N Sonenberg Proceedings of the National Academy of Sciences 113 (44), 12353-12355, 2016 | 40 | 2016 |
| Mextli Is a Novel Eukaryotic Translation Initiation Factor 4E-Binding Protein That Promotes Translation in Drosophila melanogaster G Hernández, M Miron, H Han, N Liu, J Magescas, G Tettweiler, F Frank, ... Molecular and cellular biology 33 (15), 2854-2864, 2013 | 37 | 2013 |
Nahum SonenbergGilman Cheney Professor in BiochemistryVerified email at mcgill.ca
