Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations PC Taberlay, J Achinger-Kawecka, ATL Lun, FA Buske, K Sabir, ... Genome research 26 (6), 719-731, 2016 | 365 | 2016 |
DNA methylation screening identifies driver epigenetic events of cancer cell survival DD De Carvalho, S Sharma, JS You, SF Su, PC Taberlay, TK Kelly, ... Cancer cell 21 (5), 655-667, 2012 | 338 | 2012 |
The DNA methylation landscape in cancer K Skvortsova, C Stirzaker, P Taberlay Essays in biochemistry 63 (6), 797-811, 2019 | 275 | 2019 |
Mining cancer methylomes: prospects and challenges C Stirzaker, PC Taberlay, AL Statham, SJ Clark Trends in Genetics 30 (2), 75-84, 2014 | 242 | 2014 |
Reconfiguration of nucleosome-depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer PC Taberlay, AL Statham, TK Kelly, SJ Clark, PA Jones Genome research 24 (9), 1421-1432, 2014 | 220 | 2014 |
Polycomb-repressed genes have permissive enhancers that initiate reprogramming PC Taberlay, TK Kelly, CC Liu, JS You, DD De Carvalho, TB Miranda, ... Cell 147 (6), 1283-1294, 2011 | 210 | 2011 |
OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes JS You, TK Kelly, DD De Carvalho, PC Taberlay, G Liang, PA Jones Proceedings of the National Academy of Sciences 108 (35), 14497-14502, 2011 | 165 | 2011 |
DNA methylation and cancer PC Taberlay, PA Jones Epigenetics and Disease: Pharmaceutical Opportunities, 1-23, 2011 | 155 | 2011 |
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition SJ Hogg, O Motorna, LA Cluse, TM Johanson, HD Coughlan, R Raviram, ... Molecular cell 81 (10), 2183-2200. e13, 2021 | 100 | 2021 |
Constitutively bound CTCF sites maintain 3D chromatin architecture and long-range epigenetically regulated domains A Khoury, J Achinger-Kawecka, SA Bert, GC Smith, HJ French, PL Luu, ... Nature communications 11 (1), 54, 2020 | 100 | 2020 |
Chromatin remodeler mutations in human cancers: epigenetic implications KA Skulte, L Phan, SJ Clark, PC Taberlay Epigenomics 6 (4), 397-414, 2014 | 49 | 2014 |
Neurofilament-labeled pyramidal neurons and astrocytes are deficient in DNA methylation marks in Alzheimer's disease AJ Phipps, JC Vickers, PC Taberlay, A Woodhouse Neurobiology of Aging 45, 30-42, 2016 | 44 | 2016 |
Alterations in three-dimensional organization of the cancer genome and epigenome J Achinger-Kawecka, PC Taberlay, SJ Clark Cold Spring Harbor Symposia on Quantitative Biology 81, 41-51, 2016 | 39 | 2016 |
Interplay between transcription factors and the epigenome: insight from the role of RUNX1 in leukemia KH Brettingham-Moore, PC Taberlay, AF Holloway Frontiers in immunology 6, 2015 | 39 | 2015 |
Integrated epigenomic analysis stratifies chromatin remodellers into distinct functional groups KA Giles, CM Gould, Q Du, K Skvortsova, JZ Song, MP Maddugoda, ... Epigenetics & Chromatin 12, 1-19, 2019 | 37 | 2019 |
Transcriptional and epigenetic regulation of the GM-CSF promoter by RUNX1 PC Oakford, SR James, A Qadi, AC West, SN Ray, AG Bert, PN Cockerill, ... Leukemia research 34 (9), 1203-1213, 2010 | 32 | 2010 |
Targeting epigenetic modifiers in cancer AF Holloway, PC Oakford Current medicinal chemistry 14 (24), 2540-2547, 2007 | 25 | 2007 |
BRG1 knockdown inhibits proliferation through multiple cellular pathways in prostate cancer KA Giles, CM Gould, J Achinger-Kawecka, SG Page, GR Kafer, S Rogers, ... Clinical Epigenetics 13, 1-18, 2021 | 24 | 2021 |
DNA methylation changes following DNA damage in prostate cancer cells LP Sutton, SA Jeffreys, JL Phillips, PC Taberlay, AF Holloway, M Ambrose, ... Epigenetics 14 (10), 989-1002, 2019 | 24 | 2019 |
Determinants of a transcriptionally competent environment at the GM-CSF promoter KH Brettingham-Moore, OR Sprod, X Chen, P Oakford, MF Shannon, ... Nucleic acids research 36 (8), 2639-2653, 2008 | 22 | 2008 |