Cytochrome P-450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms TD Porter, MJ Coon Journal of Biological Chemistry 266 (21), 13469-13472, 1991 | 1068 | 1991 |
Structural analysis of the FMN binding domain of NADPH-cytochrome P-450 oxidoreductase by site-directed mutagenesis AL Shen, TD Porter, TE Wilson, CB Kasper Journal of Biological Chemistry 264 (13), 7584-7589, 1989 | 362 | 1989 |
NADPH-cytochrome P-450 oxidoreductase: flavin mononucleotide and flavin adenine dinucleotide domains evolved from different flavoproteins TD Porter, CB Kasper Biochemistry 25 (7), 1682-1687, 1986 | 347 | 1986 |
The roles of cytochrome b5 in cytochrome P450 reactions TD Porter Journal of biochemical and molecular toxicology 16 (6), 311-316, 2002 | 276 | 2002 |
Policosanol inhibits cholesterol synthesis in hepatoma cells by activation of AMP-kinase DK Singh, L Li, TD Porter Journal of Pharmacology and Experimental Therapeutics 318 (3), 1020-1026, 2006 | 257 | 2006 |
Coding nucleotide sequence of rat NADPH-cytochrome P-450 oxidoreductase cDNA and identification of flavin-binding domains. TD Porter, CB Kasper Proceedings of the National Academy of Sciences 82 (4), 973-977, 1985 | 245 | 1985 |
Garlic and garlic-derived compounds inhibit human squalene monooxygenase N Gupta, TD Porter The Journal of nutrition 131 (6), 1662-1667, 2001 | 209 | 2001 |
Alcohol-inducible cytochrome P-450IIE1 lacking the hydrophobic NH2-terminal segment retains catalytic activity and is membrane-bound when expressed in Escherichia coli JR Larson, MJ Coon, TD Porter Journal of Biological Chemistry 266 (12), 7321-7324, 1991 | 198 | 1991 |
An unusual yet strongly conserved flavoprotein reductase in bacteria and mammals TD Porter Trends in biochemical sciences 16, 154-158, 1991 | 183 | 1991 |
NADPH–cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology DS Riddick, X Ding, CR Wolf, TD Porter, AV Pandey, QY Zhang, J Gu, ... Drug Metabolism and Disposition 41 (1), 12-23, 2013 | 164 | 2013 |
Cloning, heterologous expression, and enzymological characterization of human squalene monooxygenase BP Laden, Y Tang, TD Porter Archives of biochemistry and biophysics 374 (2), 381-388, 2000 | 132 | 2000 |
Inhibition of human squalene monooxygenase by tellurium compounds: evidence of interaction with vicinal sulfhydryls BP Laden, TD Porter Journal of Lipid Research 42 (2), 235-240, 2001 | 127 | 2001 |
Expression of a functional 78,000 dalton mammalian flavoprotein, NADPH-cytochrome P-450 oxidoreductase, in Escherichia coli TD Porter, TE Wilson, CB Kasper Archives of biochemistry and biophysics 254 (1), 353-367, 1987 | 115 | 1987 |
Induction and tissue-specific expression of rabbit cytochrome P450IIE1 and IIE2 genes. TD Porter, SC Khani, MJ Coon Molecular pharmacology 36 (1), 61-65, 1989 | 110 | 1989 |
Green and black tea extracts inhibit HMG-CoA reductase and activate AMP kinase to decrease cholesterol synthesis in hepatoma cells DK Singh, S Banerjee, TD Porter The Journal of nutritional biochemistry 20 (10), 816-822, 2009 | 106 | 2009 |
NADPH-cytochrome P-450 oxidoreductase gene organization correlates with structural domains of the protein TD Porter, TW Beck, CB Kasper Biochemistry 29 (42), 9814-9818, 1990 | 103 | 1990 |
cDNA and derived amino acid sequence of ethanol-inducible rabbit liver cytochrome P-450 isozyme 3a (P-450ALC). SC Khani, PG Zaphiropoulos, VS Fujita, TD Porter, DR Koop, MJ Coon Proceedings of the National Academy of Sciences 84 (3), 638-642, 1987 | 103 | 1987 |
Complementary DNA and amino acid sequence of rat liver microsomal, xenobiotic epoxide hydrolase TD Porter, TW Beck, CB Kasper Archives of biochemistry and biophysics 248 (1), 121-129, 1986 | 96 | 1986 |
Purification and properties of a shortened form of cytochrome P-450 2E1: deletion of the NH2-terminal membrane-insertion signal peptide does not alter the catalytic activities. JR Larson, MJ Coon, TD Porter Proceedings of the National Academy of Sciences 88 (20), 9141-9145, 1991 | 94 | 1991 |
Inhibition of sterol 4α-methyl oxidase is the principal mechanism by which garlic decreases cholesterol synthesis DK Singh, TD Porter The Journal of nutrition 136 (3), 759S-764S, 2006 | 90 | 2006 |