| Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides N Iwamoto, DCD Butler, N Svrzikapa, S Mohapatra, I Zlatev, DWY Sah, ... Nature biotechnology 35 (9), 845-851, 2017 | 347 | 2017 |
| Chemokine expression and control of muscle cell migration during myogenesis CA Griffin, LH Apponi, KK Long, GK Pavlath Journal of cell science 123 (18), 3052-3060, 2010 | 176 | 2010 |
| Loss of nuclear poly (A)-binding protein 1 causes defects in myogenesis and mRNA biogenesis LH Apponi, SW Leung, KR Williams, SR Valentini, AH Corbett, GK Pavlath Human molecular genetics 19 (6), 1058-1065, 2010 | 159 | 2010 |
| Actively transcribed GAL genes can be physically linked to the nuclear pore by the SAGA chromatin modifying complex R Luthra, SC Kerr, MT Harreman, LH Apponi, MB Fasken, S Ramineni, ... Journal of Biological Chemistry 282 (5), 3042-3049, 2007 | 158 | 2007 |
| PABPN 1: molecular function and muscle disease A Banerjee, LH Apponi, GK Pavlath, AH Corbett The FEBS journal 280 (17), 4230-4250, 2013 | 140 | 2013 |
| Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans CH Pak, M Garshasbi, K Kahrizi, C Gross, LH Apponi, JJ Noto, SM Kelly, ... Proceedings of the National Academy of Sciences 108 (30), 12390-12395, 2011 | 105 | 2011 |
| Inhibition of glycolate oxidase with dicer-substrate siRNA reduces calcium oxalate deposition in a mouse model of primary hyperoxaluria type 1 C Dutta, N Avitahl-Curtis, N Pursell, ML Cohen, B Holmes, R Diwanji, ... Molecular Therapy 24 (4), 770-778, 2016 | 95 | 2016 |
| RNA-binding proteins and gene regulation in myogenesis LH Apponi, AH Corbett, GK Pavlath Trends in pharmacological sciences 32 (11), 652-658, 2011 | 94 | 2011 |
| Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides P Monian, C Shivalila, G Lu, M Shimizu, D Boulay, K Bussow, M Byrne, ... Nature Biotechnology 40 (7), 1093-1102, 2022 | 77 | 2022 |
| The mitogen-activated protein kinase Slt2 regulates nuclear retention of non-heat shock mRNAs during heat shock-induced stress SR Carmody, EJ Tran, LH Apponi, AH Corbett, SR Wente Molecular and Cellular Biology, 2010 | 65 | 2010 |
| H2B ubiquitylation controls the formation of export-competent mRNP A Vitaliano-Prunier, A Babour, L Hérissant, L Apponi, T Margaritis, ... Molecular cell 45 (1), 132-139, 2012 | 64 | 2012 |
| Recognition of polyadenosine RNA by the zinc finger domain of nuclear poly (A) RNA-binding protein 2 (Nab2) is required for correct mRNA 3′-end formation SM Kelly, SW Leung, LH Apponi, AM Bramley, EJ Tran, JA Chekanova, ... Journal of Biological Chemistry 285 (34), 26022-26032, 2010 | 63 | 2010 |
| Structural modeling and mutational analysis of yeast eukaryotic translation initiation factor 5A reveal new critical residues and reinforce its involvement in protein synthesis CAO Dias, VSP Cano, SM Rangel, LH Apponi, MC Frigieri, JRC Muniz, ... The FEBS journal 275 (8), 1874-1888, 2008 | 61 | 2008 |
| Splice variants of the human ZC3H14 gene generate multiple isoforms of a zinc finger polyadenosine RNA binding protein SW Leung, LH Apponi, OE Cornejo, CM Kitchen, SR Valentini, ... Gene 439 (1-2), 71-78, 2009 | 60 | 2009 |
| Novel mouse models of oculopharyngeal muscular dystrophy (OPMD) reveal early onset mitochondrial defects and suggest loss of PABPN1 may contribute to pathology KE Vest, BL Phillips, A Banerjee, LH Apponi, EB Dammer, W Xu, D Zheng, ... Human molecular genetics 26 (17), 3235-3252, 2017 | 55 | 2017 |
| Expression of the Interleukin‐10 signaling pathway genes in individuals with down syndrome and periodontitis LB Cavalcante, MH Tanaka, JR Pires, L Henrique Apponi, ... Journal of periodontology 83 (7), 926-935, 2012 | 55 | 2012 |
| Control of mRNA stability contributes to low levels of nuclear poly (A) binding protein 1 (PABPN1) in skeletal muscle LH Apponi, AH Corbett, GK Pavlath Skeletal muscle 3, 1-9, 2013 | 48 | 2013 |
| Expression of interferon-γ, interferon-α and related genes in individuals with Down syndrome and periodontitis MH Tanaka, EMA Giro, LB Cavalcante, JR Pires, LH Apponi, SR Valentini, ... Cytokine 60 (3), 875-881, 2012 | 41 | 2012 |
| Control of backbone chemistry and chirality boost oligonucleotide splice switching activity P Kandasamy, G McClorey, M Shimizu, N Kothari, R Alam, N Iwamoto, ... Nucleic acids research 50 (10), 5443-5466, 2022 | 36 | 2022 |
| Synthetic lethality between eIF5A and Ypt1 reveals a connection between translation and the secretory pathway in yeast MC Frigieri, MVS João Luiz, LH Apponi, CF Zanelli, SR Valentini Molecular Genetics and Genomics 280, 211-221, 2008 | 36 | 2008 |
