Dierssen Mara

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Xavier Estivill MD PhDqGenomics (Quantitative Genomics Laboratories)Verified email at qgenomics.com
Rafael de La Torre FornellDirector del Instituto del Hospital del Mar de Investigaciones (IMIM), Profesor de Toxicología Asociado a la UPFVerified email at upf.edu
Yann HeraultIGBMC, CELPHEDIA-PHENOMIN-ICSVerified email at igbmc.fr
Stylianos E. AntonarakisProfessor of Genetic Medicine, University of Geneva Medical SchoolVerified email at unige.ch
adolf tobeñaemeritus professor of psychiatryVerified email at uab.cat
Javier DeFelipeInstituto Cajal (CSIC) and Universidad Politécnica de Madrid, SpainVerified email at cajal.csic.es
Caty CasasScientist and Lecturer in Physiology, Institute of Neuroscience, Universitat Autònoma de BarcelonaVerified email at uab.es
Ruth Benavides-PiccioneCajal Institute (CSIC) and Universidad Politecnica MadridVerified email at cajal.csic.es
Inmaculada Ballesteros Yanez (https://...University of Castilla-La Mancha, Faculty of Medicine (https://ror.org/05r78ng12)Verified email at uclm.es
eduardo sorianoUniversity of Barcelona, SpainVerified email at ub.edu
Alberto Fernández TeruelProfesor Titular, Departamento de Psiquiatría y Medicina Legal, Universidad Autónoma de BarcelonaVerified email at uab.cat
Arnau Busquets-garciaNeurocenter MagendieVerified email at inserm.fr
Jesus PujolHospital del Mar, BarcelonaVerified email at comb.cat
Salvador Martinez PerezInstituto de NeurocienciasVerified email at umh.es
José M. Delgado-García (0000-0001-7...Universidad Pablo de Olavide, Seville, SpainVerified email at upo.es
Carmen Agustín-PavónUniversitat de ValènciaVerified email at uv.es
Manuel MegíasAssitant professor in Biology, University of VigoVerified email at uvigo.es
Jordi AlberchFull Professor, Medical School, Institute of Neurosciences, University of BarcelonaVerified email at ub.edu
Valverde OlgaFull Professor. Department of Medicine and Life Sciences. Universitat Pompeu Fabra.Verified email at upf.edu
Jose V. Sanchez-MutNeuroscience Institute of Alicante, CSIC-UMHVerified email at umh.es

Dierssen Mara

Center for Genomic Regulation

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Neuroscience


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Cognitive deficits and associated neurological complications in individuals with Down's syndrome IT Lott, M Dierssen The Lancet Neurology 9 (6), 623-633, 2010	652	2010
Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down’s syndrome X Altafaj, M Dierssen, C Baamonde, E Martí, J Visa, J Guimerà, M Oset, ... Human molecular genetics 10 (18), 1915-1923, 2001	495	2001
Dyrk1A Haploinsufficiency Affects Viability and Causes Developmental Delay and Abnormal Brain Morphology in Mice V Fotaki, M Dierssen, S Alcántara, S Martínez, E Martí, C Casas, J Visa, ... Molecular and cellular biology 22 (18), 6636-6647, 2002	385	2002
Down syndrome: the brain in trisomic mode M Dierssen Nature Reviews Neuroscience 13 (12), 844-858, 2012	369	2012
Epigallocatechin‐3‐gallate, a DYRK1A inhibitor, rescues cognitive deficits in D own syndrome mouse models and in humans R De la Torre, S De Sola, M Pons, A Duchon, MM de Lagran, M Farré, ... Molecular nutrition & food research 58 (2), 278-288, 2014	352	2014
Erbb4 deletion from fast-spiking interneurons causes schizophrenia-like phenotypes I Del Pino, C García-Frigola, N Dehorter, JR Brotons-Mas, ... Neuron 79 (6), 1152-1168, 2013	332	2013
A behavioral assessment of Ts65Dn mice: a putative Down syndrome model RM Escorihuela, A Fernández-Teruel, IF Vallina, C Baamonde, ... Neuroscience letters 199 (2), 143-146, 1995	311	1995
Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 … R de la Torre, S de Sola, G Hernandez, M Farré, J Pujol, J Rodriguez, ... The Lancet Neurology 15 (8), 801-810, 2016	305	2016
Potential role of olive oil phenolic compounds in the prevention of neurodegenerative diseases J Rodríguez-Morató, L Xicota, M Fitó, M Farré, M Dierssen, R De la Torre Molecules 20 (3), 4655-4680, 2015	281	2015
Targeting the endocannabinoid system in the treatment of fragile X syndrome A Busquets-Garcia, M Gomis-González, T Guegan, C Agustín-Pavón, ... Nature medicine 19 (5), 603-607, 2013	275	2013
Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice M Garriga-Canut, C Agustín-Pavón, F Herrmann, A Sánchez, M Dierssen, ... Proceedings of the National Academy of Sciences 109 (45), E3136-E3145, 2012	253	2012
Dendritic pathology in mental retardation: from molecular genetics to neurobiology M Dierssen, GJA Ramakers Genes, Brain and Behavior 5, 48-60, 2006	245	2006
Differential effects of environmental enrichment on behavior and learning of male and female Ts65Dn mice, a model for Down syndrome C Martı́nez-Cué, C Baamonde, M Lumbreras, J Paz, MT Davisson, ... Behavioural brain research 134 (1-2), 185-200, 2002	228	2002
Hippocampal volume and neuronal number in Ts65Dn mice: a murine model of Down syndrome AM Insausti, M Megıas, D Crespo, LM Cruz-Orive, M Dierssen, TF Vallina, ... Neuroscience letters 253 (3), 175-178, 1998	214	1998
Impaired short-and long-term memory in Ts65Dn mice, a model for Down syndrome RM Escorihuela, IF Vallina, C Martı́nez-Cué, C Baamonde, M Dierssen, ... Neuroscience letters 247 (2-3), 171-174, 1998	202	1998
Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models I Ferrer, M Barrachina, B Puig, MM De Lagrán, E Martí, J Avila, ... Neurobiology of disease 20 (2), 392-400, 2005	195	2005
Alterations of neocortical pyramidal cell phenotype in the Ts65Dn mouse model of Down syndrome: effects of environmental enrichment M Dierssen, R Benavides-Piccione, C Martínez-Cué, X Estivill, J Flórez, ... Cerebral cortex 13 (7), 758-764, 2003	194	2003
Aneuploidy: from a physiological mechanism of variance to Down syndrome M Dierssen, Y Herault, X Estivill Physiological reviews, 2009	182	2009
Down syndrome: from understanding the neurobiology to therapy K Gardiner, Y Herault, IT Lott, SE Antonarakis, RH Reeves, M Dierssen Journal of Neuroscience 30 (45), 14943-14945, 2010	178	2010
Fetal life in Down syndrome starts with normal neuronal density but impaired dendritic spines and synaptosomal structure R Weitzdoerfer, M Dierssen, M Fountoulakis, G Lubec Protein expression in Down syndrome brain, 59-70, 2001	174	2001

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