Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease S Jawhar, A Trawicka, C Jenneckens, TA Bayer, O Wirths Neurobiology of aging 33 (1), 196. e29-196. e40, 2012 | 641 | 2012 |
Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Aβ42 accumulation in a novel Alzheimer transgenic model C Casas, N Sergeant, JM Itier, V Blanchard, O Wirths, N Van Der Kolk, ... The American journal of pathology 165 (4), 1289-1300, 2004 | 552 | 2004 |
A modified β‐amyloid hypothesis: intraneuronal accumulation of the β‐amyloid peptide–the first step of a fatal cascade O Wirths, G Multhaup, TA Bayer Journal of neurochemistry 91 (3), 513-520, 2004 | 534 | 2004 |
Genetic and non-genetic vulnerability factors in schizophrenia: the basis of the “two hit hypothesis” TA Bayer, P Falkai, W Maier Journal of psychiatric research 33 (6), 543-548, 1999 | 472 | 1999 |
Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier SE Storck, S Meister, J Nahrath, JN Meißner, N Schubert, A Di Spiezio, ... The Journal of clinical investigation 126 (1), 123-136, 2016 | 433 | 2016 |
Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Aβ production in APP23 transgenic mice TA Bayer, S Schäfer, A Simons, A Kemmling, T Kamer, R Tepests, ... Proceedings of the National Academy of Sciences 100 (24), 14187-14192, 2003 | 433 | 2003 |
Intraneuronal Aβ accumulation precedes plaque formation in β-amyloid precursor protein and presenilin-1 double-transgenic mice O Wirths, G Multhaup, C Czech, V Blanchard, S Moussaoui, G Tremp, ... Neuroscience letters 306 (1-2), 116-120, 2001 | 433 | 2001 |
Evidence for activation of microglia in patients with psychiatric illnesses TA Bayer, R Buslei, L Havas, P Falkai Neuroscience letters 271 (2), 126-128, 1999 | 431 | 1999 |
Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease C Schmitz, BPF Rutten, A Pielen, S Schäfer, O Wirths, G Tremp, C Czech, ... The American journal of pathology 164 (4), 1495-1502, 2004 | 389 | 2004 |
Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease M Heverin, N Bogdanovic, D Lütjohann, T Bayer, I Pikuleva, L Bretillon, ... Journal of lipid research 45 (1), 186-193, 2004 | 380 | 2004 |
Time sequence of maturation of dystrophic neurites associated with Aβ deposits in APP/PS1 transgenic mice V Blanchard, S Moussaoui, C Czech, N Touchet, B Bonici, M Planche, ... Experimental neurology 184 (1), 247-263, 2003 | 361 | 2003 |
Intracellular accumulation of amyloid-Beta-a predictor for synaptic dysfunction and neuron loss in Alzheimer's disease TA Bayer, O Wirths Frontiers in aging neuroscience 2, 1359, 2010 | 313 | 2010 |
Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease S Scheuermann, B Hambsch, L Hesse, J Stumm, C Schmidt, D Beher, ... Journal of Biological Chemistry 276 (36), 33923-33929, 2001 | 281 | 2001 |
A genetic variation of the inflammatory cytokine interleukin‐6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease A Papassotiropoulos, M Bagli, F Jessen, TA Bayer, W Maier, ML Rao, ... Annals of Neurology: Official Journal of the American Neurological …, 1999 | 271 | 1999 |
Key factors in Alzheimer's disease: β‐amyloid precursor protein processing, metabolism and intraneuronal transport TA Bayer, O Wirths, K Majtényi, T Hartmann, G Multhaup, K Beyreuther, ... Brain Pathology 11 (1), 1-11, 2001 | 264 | 2001 |
Pyroglutamate amyloid-β (Aβ): a hatchet man in Alzheimer disease S Jawhar, O Wirths, TA Bayer Journal of Biological Chemistry 286 (45), 38825-38832, 2011 | 263 | 2011 |
Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease Z Yin, D Raj, N Saiepour, D Van Dam, N Brouwer, IR Holtman, BJL Eggen, ... Neurobiology of aging 55, 115-122, 2017 | 256 | 2017 |
Review of immunological and immunopathological findings in schizophrenia M Rothermundt, V Arolt, TA Bayer Brain, behavior, and immunity 15 (4), 319-339, 2001 | 252 | 2001 |
Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model O Wirths, H Breyhan, H Cynis, S Schilling, HU Demuth, TA Bayer Acta neuropathologica 118, 487-496, 2009 | 221 | 2009 |
No evidence for astrogliosis in brains of schizophrenic patients. A post‐mortem study Falkai, Honer, Bogerts, Majtenyi, Bayer Neuropathology and applied neurobiology 25 (1), 47-52, 1999 | 211 | 1999 |