Gαo is a major determinant of cAMP signaling in the pathophysiology of movement disorders BS Muntean, I Masuho, M Dao, LP Sutton, S Zucca, H Iwamoto, DN Patil, ... Cell reports 34 (5), 2021 | 82 | 2021 |
Novel GNB1 mutations disrupt assembly and function of G protein heterotrimers and cause global developmental delay in humans K Lohmann, I Masuho, DN Patil, H Baumann, E Hebert, S Steinrücke, ... Human molecular genetics 26 (6), 1078-1086, 2017 | 73 | 2017 |
Lipid binding promotes oligomerization and focal adhesion activity of vinculin K Chinthalapudi, ES Rangarajan, DN Patil, EM George, DT Brown, T Izard Journal of Cell Biology 207 (5), 643-656, 2014 | 69 | 2014 |
Structural and functional evolution of chitinase‐like proteins from plants P Kesari, DN Patil, P Kumar, S Tomar, AK Sharma, P Kumar Proteomics 15 (10), 1693-1705, 2015 | 65 | 2015 |
Synaptic adhesion protein ELFN1 is a selective allosteric modulator of group III metabotropic glutamate receptors in trans HA Dunn, DN Patil, Y Cao, C Orlandi, KA Martemyanov Proceedings of the National Academy of Sciences 115 (19), 5022-5027, 2018 | 64 | 2018 |
GNB5 mutation causes a novel neuropsychiatric disorder featuring attention deficit hyperactivity disorder, severely impaired language development and normal cognition HE Shamseldin, I Masuho, A Alenizi, S Alyamani, DN Patil, N Ibrahim, ... Genome biology 17, 1-9, 2016 | 50 | 2016 |
Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex DN Patil, S Singh, T Laboute, TS Strutzenberg, X Qiu, D Wu, SJ Novick, ... Science 375 (6576), 86-91, 2022 | 45 | 2022 |
Structural basis for dual inhibitory role of tamarind K unitz inhibitor (TKI) against factor X a and trypsin DN Patil, A Chaudhary, AK Sharma, S Tomar, P Kumar The FEBS Journal 279 (24), 4547-4564, 2012 | 41 | 2012 |
Orphan receptor GPR158 serves as a metabotropic glycine receptor: mGlyR T Laboute, S Zucca, M Holcomb, DN Patil, C Garza, BA Wheatley, RN Roy, ... Science 379 (6639), 1352-1358, 2023 | 38 | 2023 |
Structure-function studies of DNA binding domain of response regulator KdpE reveals equal affinity interactions at DNA half-sites A Narayanan, LN Paul, S Tomar, DN Patil, P Kumar, DA Yernool PloS one 7 (1), e30102, 2012 | 32 | 2012 |
Structural investigation of a novel N-acetyl glucosamine binding chi-lectin which reveals evolutionary relationship with class III chitinases DN Patil, M Datta, A Dev, S Dhindwal, N Singh, P Dasauni, S Kundu, ... PLoS One 8 (5), e63779, 2013 | 28 | 2013 |
Biochemical studies and ligand-bound structures of biphenyl dehydrogenase from Pandoraea pnomenusa strain B-356 reveal a basis for broad specificity of the enzyme S Dhindwal, DN Patil, M Mohammadi, M Sylvestre, S Tomar, P Kumar Journal of Biological Chemistry 286 (42), 37011-37022, 2011 | 28 | 2011 |
Isolation, purification, crystallization and preliminary crystallographic studies of chitinase from tamarind (Tamarindus indica) seeds DN Patil, M Datta, A Chaudhary, S Tomar, A Kumar Sharma, P Kumar Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009 | 28 | 2009 |
Structural organization of a major neuronal G protein regulator, the RGS7-Gβ5-R7BP complex DN Patil, ES Rangarajan, SJ Novick, BD Pascal, DJ Kojetin, PR Griffin, ... Elife 7, e42150, 2018 | 27 | 2018 |
Lipid-directed vinculin dimerization K Chinthalapudi, DN Patil, ES Rangarajan, C Rader, T Izard Biochemistry 54 (17), 2758-2768, 2015 | 23 | 2015 |
Molecular deconvolution platform to establish disease mechanisms by surveying GPCR signaling I Masuho, S Chavali, BS Muntean, NK Skamangas, K Simonyan, DN Patil, ... Cell Reports 24 (3), 557-568. e5, 2018 | 19 | 2018 |
Conformational flexibility determines the Nf2/merlin tumor suppressor functions MC Primi, ES Rangarajan, DN Patil, T Izard Matrix Biology Plus 12, 100074, 2021 | 14 | 2021 |
Purification, crystallization and preliminary crystallographic studies of a Kunitz-type proteinase inhibitor from tamarind (Tamarindus indica) seeds DN Patil, A Chaudhry, AK Sharma, S Tomar, P Kumar Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009 | 11 | 2009 |
Purification and biophysical characterization of an 11S globulin from Wrightia tinctoria exhibiting hemagglutinating activity P Kumar, D N Patil, A Chaudhary, S Tomar, D Yernool, N Singh, ... Protein and Peptide Letters 20 (5), 499-509, 2013 | 8 | 2013 |
A high-throughput time-resolved fluorescence energy transfer assay to screen for modulators of RGS7/Gβ5/R7BP complex BS Muntean, DN Patil, F Madoux, J Fossetta, L Scampavia, TP Spicer, ... ASSAY and Drug Development Technologies 16 (3), 150-161, 2018 | 7 | 2018 |