Ultrasensitive single-cell proteomics workflow identifies> 1000 protein groups per mammalian cell Y Cong, K Motamedchaboki, SA Misal, Y Liang, AJ Guise, T Truong, ... Chemical science 12 (3), 1001-1006, 2021 | 225 | 2021 |
Improved single-cell proteome coverage using narrow-bore packed NanoLC columns and ultrasensitive mass spectrometry Y Cong, Y Liang, K Motamedchaboki, R Huguet, T Truong, R Zhao, ... Analytical chemistry 92 (3), 2665-2671, 2020 | 163 | 2020 |
Spatially resolved proteome mapping of laser capture microdissected tissue with automated sample transfer to nanodroplets Y Zhu, M Dou, PD Piehowski, Y Liang, F Wang, RK Chu, WB Chrisler, ... Molecular & Cellular Proteomics 17 (9), 1864-1874, 2018 | 130 | 2018 |
Fully automated sample processing and analysis workflow for low-input proteome profiling Y Liang, H Acor, MA McCown, AJ Nwosu, H Boekweg, NB Axtell, ... Analytical chemistry 93 (3), 1658-1666, 2020 | 102 | 2020 |
Label-free profiling of up to 200 single-cell proteomes per day using a dual-column nanoflow liquid chromatography platform KGI Webber, T Truong, SM Johnston, SE Zapata, Y Liang, JM Davis, ... Analytical chemistry 94 (15), 6017-6025, 2022 | 63 | 2022 |
Benchtop-compatible sample processing workflow for proteome profiling of< 100 mammalian cells K Xu, Y Liang, PD Piehowski, M Dou, KC Schwarz, R Zhao, RL Sontag, ... Analytical and bioanalytical chemistry 411, 4587-4596, 2019 | 52 | 2019 |
Data‐dependent acquisition with precursor coisolation improves proteome coverage and measurement throughput for label‐free single‐cell proteomics T Truong, KGI Webber, S Madisyn Johnston, H Boekweg, CM Lindgren, ... Angewandte Chemie 135 (34), e202303415, 2023 | 51 | 2023 |
Nanowell-mediated two-dimensional liquid chromatography enables deep proteome profiling of< 1000 mammalian cells M Dou, Y Zhu, A Liyu, Y Liang, J Chen, PD Piehowski, K Xu, R Zhao, ... Chemical science 9 (34), 6944-6951, 2018 | 43 | 2018 |
Spatially resolved proteome profiling of< 200 cells from tomato fruit pericarp by integrating laser-capture microdissection with nanodroplet sample preparation Y Liang, Y Zhu, M Dou, K Xu, RK Chu, WB Chrisler, R Zhao, KK Hixson, ... Analytical chemistry 90 (18), 11106-11114, 2018 | 41 | 2018 |
3D-printed high-density droplet array chip for miniaturized protein crystallization screening under vapor diffusion mode YR Liang, LN Zhu, J Gao, HX Zhao, Y Zhu, S Ye, Q Fang ACS applied materials & interfaces 9 (13), 11837-11845, 2017 | 40 | 2017 |
Chemiluminescent detection of cell apoptosis enzyme by gold nanoparticle-based resonance energy transfer assay X Huang, Y Liang, L Ruan, J Ren Analytical and bioanalytical chemistry 406, 5677-5684, 2014 | 29 | 2014 |
In-Depth mass spectrometry-Based proteomics of formalin-Fixed, Paraffin-Embedded Tissues with a Spatial Resolution of 50–200 μm AJ Nwosu, SA Misal, T Truong, RH Carson, KGI Webber, NB Axtell, ... Journal of proteome research 21 (9), 2237-2245, 2022 | 28 | 2022 |
Adapting a low-cost and open-source commercial pipetting robot for nanoliter liquid handling EEAW Councill, NB Axtell, T Truong, Y Liang, AL Aposhian, KGI Webber, ... SLAS TECHNOLOGY: Translating Life Sciences Innovation 26 (3), 311-319, 2021 | 28 | 2021 |
Cell‐type‐specific proteomics analysis of a small number of plant cells by integrating laser capture microdissection with a nanodroplet sample processing platform VK Balasubramanian, SO Purvine, Y Liang, RT Kelly, L Pasa‐Tolic, ... Current Protocols 1 (5), e153, 2021 | 23 | 2021 |
Single Cell Proteome Mapping of Tissue Heterogeneity Using Microfluidic Nanodroplet Sample Processing and Ultrasensitive LC-MS R Kelly, Y Zhu, Y Liang, Y Cong, P Piehowski, M Dou, R Zhao, WJ Qian, ... Journal of Biomolecular Techniques: JBT 30 (Suppl), S61, 2019 | 22 | 2019 |
HyperSCP: Combining isotopic and isobaric labeling for higher throughput single-cell proteomics Y Liang, T Truong, AJ Saxton, H Boekweg, SH Payne, PM Van Ry, ... Analytical chemistry 95 (20), 8020-8027, 2023 | 21 | 2023 |
TDP-43-stratified single-cell proteomics of postmortem human spinal motor neurons reveals protein dynamics in amyotrophic lateral sclerosis AJ Guise, SA Misal, R Carson, JH Chu, H Boekweg, D Van Der Watt, ... Cell reports 43 (1), 2024 | 15 | 2024 |
In-depth mass spectrometry-based single-cell and nanoscale proteomics Y Liang, T Truong, Y Zhu, RT Kelly Leukemia Stem Cells: Methods and Protocols, 159-179, 2021 | 8 | 2021 |
TDP-43-stratified single-cell proteomic profiling of postmortem human spinal motor neurons reveals protein dynamics in amyotrophic lateral sclerosis AJ Guise, SA Misal, R Carson, H Boekweg, D Van Der Watt, T Truong, ... bioRxiv, 2023 | 5 | 2023 |
Boosting the Sensitivity of Quantitative Single-Cell Proteomics with Activated Ion-Tandem Mass Tags (AI-TMT) T Peters-Clarke, Y Liang, KL Mertz, KW Lee, MS Westphall, JD Hinkle, ... bioRxiv, 2024.02. 24.581874, 2024 | 2 | 2024 |