Blu-Ice and the Distributed Control System: software for data acquisition and instrument control at macromolecular crystallography beamlines TM McPhillips, SE McPhillips, HJ Chiu, AE Cohen, AM Deacon, PJ Ellis, ... Journal of synchrotron radiation 9 (6), 401-406, 2002 | 1272 | 2002 |
Architecture of the synaptotagmin–SNARE machinery for neuronal exocytosis Q Zhou, Y Lai, T Bacaj, M Zhao, AY Lyubimov, M Uervirojnangkoorn, ... Nature 525 (7567), 62-67, 2015 | 348 | 2015 |
MitoNEET is a uniquely folded 2Fe–2S outer mitochondrial membrane protein stabilized by pioglitazone ML Paddock, SE Wiley, HL Axelrod, AE Cohen, M Roy, EC Abresch, ... Proceedings of the National Academy of Sciences 104 (36), 14342-14347, 2007 | 327 | 2007 |
An automated system to mount cryo-cooled protein crystals on a synchrotron beamline, using compact sample cassettes and a small-scale robot AE Cohen, PJ Ellis, MD Miller, AM Deacon, RP Phizackerley Journal of applied crystallography 35 (6), 720-726, 2002 | 325 | 2002 |
Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography DA Keedy, LR Kenner, M Warkentin, RA Woldeyes, JB Hopkins, ... Elife 4, e07574, 2015 | 190 | 2015 |
Goniometer-based femtosecond crystallography with X-ray free electron lasers AE Cohen, SM Soltis, A González, L Aguila, R Alonso-Mori, CO Barnes, ... Proceedings of the National Academy of Sciences 111 (48), 17122-17127, 2014 | 160 | 2014 |
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking M Schuller, GJ Correy, S Gahbauer, D Fearon, T Wu, RE Díaz, ID Young, ... Science advances 7 (16), eabf8711, 2021 | 154 | 2021 |
How directed evolution reshapes the energy landscape in an enzyme to boost catalysis R Otten, RAP Pádua, HA Bunzel, V Nguyen, W Pitsawong, MK Patterson, ... Science 370 (6523), 1442-1446, 2020 | 151 | 2020 |
New paradigm for macromolecular crystallography experiments at SSRL: automated crystal screening and remote data collection SM Soltis, AE Cohen, A Deacon, T Eriksson, A González, S McPhillips, ... Acta Crystallographica Section D: Biological Crystallography 64 (12), 1210-1221, 2008 | 142 | 2008 |
Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2 AR Conlan, HL Axelrod, AE Cohen, EC Abresch, J Zuris, D Yee, ... Journal of molecular biology 392 (1), 143-153, 2009 | 140 | 2009 |
Acoustic injectors for drop-on-demand serial femtosecond crystallography CG Roessler, R Agarwal, M Allaire, R Alonso-Mori, B Andi, JFR Bachega, ... Structure 24 (4), 631-640, 2016 | 134 | 2016 |
Strategies for sample delivery for femtosecond crystallography I Martiel, HM Müller-Werkmeister, AE Cohen Biological Crystallography 75 (2), 160-177, 2019 | 129 | 2019 |
The Crystal Structure of Pichia pastoris Lysyl Oxidase AP Duff, AE Cohen, PJ Ellis, JA Kuchar, DB Langley, EM Shepard, ... Biochemistry 42 (51), 15148-15157, 2003 | 117 | 2003 |
The DDB1–DCAF1–Vpr–UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction Y Wu, X Zhou, CO Barnes, M DeLucia, AE Cohen, AM Gronenborn, J Ahn, ... Nature structural & molecular biology 23 (10), 933-940, 2016 | 115 | 2016 |
Crystal structure of a transcribing RNA polymerase II complex reveals a complete transcription bubble CO Barnes, M Calero, I Malik, BW Graham, H Spahr, G Lin, AE Cohen, ... Molecular cell 59 (2), 258-269, 2015 | 114 | 2015 |
Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine J Pan, Q Chen, D Willenbring, K Yoshida, T Tillman, OB Kashlan, ... Nature communications 3 (1), 714, 2012 | 113 | 2012 |
Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope CO Barnes, HB Gristick, NT Freund, A Escolano, AY Lyubimov, ... Nature communications 9 (1), 1251, 2018 | 109 | 2018 |
Structure of the pentameric ligand-gated ion channel GLIC bound with anesthetic ketamine J Pan, Q Chen, D Willenbring, D Mowrey, XP Kong, A Cohen, CB Divito, ... Structure 20 (9), 1463-1469, 2012 | 95 | 2012 |
Capture and X-ray diffraction studies of protein microcrystals in a microfluidic trap array AY Lyubimov, TD Murray, A Koehl, IE Araci, M Uervirojnangkoorn, ... Acta Crystallographica Section D: Biological Crystallography 71 (4), 928-940, 2015 | 88 | 2015 |
Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis M Dasgupta, D Budday, SHP De Oliveira, P Madzelan, ... Proceedings of the National Academy of Sciences 116 (51), 25634-25640, 2019 | 81 | 2019 |