The spectrum of latent tuberculosis: rethinking the biology and intervention strategies CE Barry 3rd, HI Boshoff, V Dartois, T Dick, S Ehrt, JA Flynn, ... Nature Reviews Microbiology 7 (12), 845-855, 2009 | 1729 | 2009 |
Spiroindolones, a potent compound class for the treatment of malaria M Rottmann, C McNamara, BKS Yeung, MCS Lee, B Zou, B Russell, ... science 329 (5996), 1175-1180, 2010 | 1268 | 2010 |
Linezolid for treatment of chronic extensively drug-resistant tuberculosis M Lee, J Lee, MW Carroll, H Choi, S Min, T Song, LE Via, LC Goldfeder, ... New England Journal of Medicine 367 (16), 1508-1518, 2012 | 737 | 2012 |
The association between sterilizing activity and drug distribution into tuberculosis lesions B Prideaux, LE Via, MD Zimmerman, S Eum, J Sarathy, P O'brien, C Chen, ... Nature medicine 21 (10), 1223-1227, 2015 | 506 | 2015 |
Spirotetrahydro β-carbolines (spiroindolones): a new class of potent and orally efficacious compounds for the treatment of malaria BKS Yeung, B Zou, M Rottmann, SB Lakshminarayana, SH Ang, ... Journal of medicinal chemistry 53 (14), 5155-5164, 2010 | 479 | 2010 |
The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells V Dartois Nature Reviews Microbiology 12 (3), 159-167, 2014 | 464 | 2014 |
An adenosine nucleoside inhibitor of dengue virus Z Yin, YL Chen, W Schul, QY Wang, F Gu, J Duraiswamy, RR Kondreddi, ... Proceedings of the National Academy of Sciences 106 (48), 20435-20439, 2009 | 409 | 2009 |
Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses A Lenaerts, CE Barry III, V Dartois Immunological reviews 264 (1), 288-307, 2015 | 382 | 2015 |
Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing YJ Zhang, MC Reddy, TR Ioerger, AC Rothchild, V Dartois, BM Schuster, ... Cell 155 (6), 1296-1308, 2013 | 360 | 2013 |
A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy K Pethe, PC Sequeira, S Agarwalla, K Rhee, K Kuhen, WY Phong, V Patel, ... Nature communications 1 (1), 57, 2010 | 338 | 2010 |
Anti-tuberculosis treatment strategies and drug development: challenges and priorities VA Dartois, EJ Rubin Nature Reviews Microbiology 20 (11), 685-701, 2022 | 332 | 2022 |
Inflammatory signaling in human tuberculosis granulomas is spatially organized MJ Marakalala, RM Raju, K Sharma, YJ Zhang, EA Eugenin, B Prideaux, ... Nature medicine 22 (5), 531-538, 2016 | 329 | 2016 |
High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions B Prideaux, V Dartois, D Staab, DM Weiner, A Goh, LE Via, CE Barry III, ... Analytical chemistry 83 (6), 2112-2118, 2011 | 292 | 2011 |
ClpP of Bacillus subtilis is required for competence development, motility, degradative enzyme synthesis, growth at high temperature and sporulation T Msadek, V Dartois, F Kunst, ML Herbaud, F Denizot, G Rapoport Molecular microbiology 27 (5), 899-914, 1998 | 290 | 1998 |
Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis BB Mishra, RR Lovewell, AJ Olive, G Zhang, W Wang, E Eugenin, ... Nature microbiology 2 (7), 1-11, 2017 | 282 | 2017 |
Comprehensive analysis of methods used for the evaluation of compounds against Mycobacterium tuberculosis SG Franzblau, MA DeGroote, SH Cho, K Andries, E Nuermberger, ... Tuberculosis 92 (6), 453-488, 2012 | 269 | 2012 |
NTM drug discovery: status, gaps and the way forward ML Wu, DB Aziz, V Dartois, T Dick Drug discovery today 23 (8), 1502-1519, 2018 | 267 | 2018 |
Fatty acid synthesis is required for breast cancer brain metastasis GB Ferraro, A Ali, A Luengo, DP Kodack, A Deik, KL Abbott, D Bezwada, ... Nature cancer 2 (4), 414-428, 2021 | 236 | 2021 |
Cloning, nucleotide sequence and expression in Escherichia coli of a lipase gene from Bacillus subtilis 168 V Dartois, A Baulard, K Schanck, C Colson Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1131 (3 …, 1992 | 211 | 1992 |
Extreme drug tolerance of Mycobacterium tuberculosis in caseum JP Sarathy, LE Via, D Weiner, L Blanc, H Boshoff, EA Eugenin, ... Antimicrobial agents and chemotherapy 62 (2), 10.1128/aac. 02266-17, 2018 | 208 | 2018 |