| Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy KL Swingle, HC Safford, HC Geisler, AG Hamilton, AS Thatte, ... Journal of the American Chemical Society 145 (8), 4691-4706, 2023 | 88 | 2023 |
| Molecular mechanisms of membrane curvature sensing by a disordered protein WF Zeno, AS Thatte, L Wang, WT Snead, EM Lafer, JC Stachowiak Journal of the American Chemical Society 141 (26), 10361-10371, 2019 | 77 | 2019 |
| In vivo mRNA CAR T cell engineering via targeted ionizable lipid nanoparticles with extrahepatic tropism MM Billingsley, N Gong, AJ Mukalel, AS Thatte, R El‐Mayta, SK Patel, ... Small 20 (11), 2304378, 2024 | 49 | 2024 |
| Responsive biomaterials: optimizing control of cancer immunotherapy L Xue, AS Thatte, D Mai, RM Haley, N Gong, X Han, K Wang, ... Nature Reviews Materials 9 (2), 100-118, 2024 | 45 | 2024 |
| Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines SJ Shepherd, X Han, AJ Mukalel, R El-Mayta, AS Thatte, J Wu, MS Padilla, ... Proceedings of the National Academy of Sciences 120 (33), e2303567120, 2023 | 45 | 2023 |
| Clathrin senses membrane curvature WF Zeno, JB Hochfelder, AS Thatte, L Wang, AK Gadok, CC Hayden, ... Biophysical Journal 120 (5), 818-828, 2021 | 38 | 2021 |
| Structured and intrinsically disordered domains within Amphiphysin1 work together to sense and drive membrane curvature WF Zeno, WT Snead, AS Thatte, JC Stachowiak Soft Matter 15 (43), 8706-8717, 2019 | 31 | 2019 |
| Antigen presenting cell mimetic lipid nanoparticles for rapid mRNA CAR T cell cancer immunotherapy AE Metzloff, MS Padilla, N Gong, MM Billingsley, X Han, M Merolle, D Mai, ... Advanced Materials, 2313226, 2024 | 25 | 2024 |
| Orthogonal design of experiments for engineering of lipid nanoparticles for mRNA delivery to the placenta HC Safford, KL Swingle, HC Geisler, AG Hamilton, AS Thatte, ... Small 20 (41), 2303568, 2024 | 20 | 2024 |
| Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery SK Patel, MM Billingsley, AJ Mukalel, AS Thatte, AG Hamilton, N Gong, ... Theranostics 14 (1), 1, 2024 | 20 | 2024 |
| Delivery of plasmid DNA by ionizable lipid nanoparticles to induce CAR expression in T cells PHDM Prazeres, H Ferreira, PAC Costa, W da Silva, MT Alves, M Padilla, ... International Journal of Nanomedicine, 5891-5904, 2023 | 17 | 2023 |
| mRNA Lipid Nanoparticles for Ex Vivo Engineering of Immunosuppressive T Cells for Autoimmunity Therapies AS Thatte, AG Hamilton, BE Nachod, AJ Mukalel, MM Billingsley, ... Nano Letters 23 (22), 10179-10188, 2023 | 13 | 2023 |
| Ionizable lipid nanoparticle-mediated trail mRNA delivery in the tumor microenvironment to inhibit colon cancer progression WN da Silva, PA Carvalho Costa, SRA Scalzo Júnior, HAS Ferreira, ... International Journal of Nanomedicine, 2655-2673, 2024 | 12 | 2024 |
| Oxidized mRNA Lipid Nanoparticles for In Situ Chimeric Antigen Receptor Monocyte Engineering AJ Mukalel, AG Hamilton, MM Billingsley, J Li, AS Thatte, X Han, ... Advanced Functional Materials, 2312038, 2024 | 12 | 2024 |
| EGFR-targeted ionizable lipid nanoparticles enhance in vivo mRNA delivery to the placenta HC Geisler, AA Ghalsasi, HC Safford, KL Swingle, AS Thatte, AJ Mukalel, ... Journal of Controlled Release 371, 455-469, 2024 | 9 | 2024 |
| High-Throughput In Vivo Screening Identifies Differential Influences on mRNA Lipid Nanoparticle Immune Cell Delivery by Administration Route AG Hamilton, KL Swingle, AS Thatte, AJ Mukalel, HC Safford, ... ACS nano, 2024 | 7 | 2024 |
| Emerging strategies for nanomedicine in autoimmunity AS Thatte, MM Billingsley, D Weissman, JR Melamed, MJ Mitchell Advanced Drug Delivery Reviews, 115194, 2024 | 6 | 2024 |
| In utero delivery of targeted ionizable lipid nanoparticles facilitates in vivo gene editing of hematopoietic stem cells R Palanki, JS Riley, SK Bose, V Luks, A Dave, N Kus, BM White, ... Proceedings of the National Academy of Sciences 121 (32), e2400783121, 2024 | 4 | 2024 |
| Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia KL Swingle, AG Hamilton, HC Safford, HC Geisler, AS Thatte, R Palanki, ... Nature 637 (8045), 412-421, 2025 | 1 | 2025 |
| Fine-tuning extracellular fluid viscosity enhances gene delivery AS Thatte, D Kim, MJ Mitchell Nature Chemical Engineering 1 (9), 559-560, 2024 | | 2024 |
Michael J. MitchellAssociate Professor of Bioengineering, University of PennsylvaniaVerified email at seas.upenn.edu
