| Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy RGG Russell, NB Watts, FH Ebetino, MJ Rogers Osteoporosis international 19, 733-759, 2008 | 1841 | 2008 |
| Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates JE Dunford, K Thompson, FP Coxon, SP Luckman, FM Hahn, CD Poulter, ... Journal of Pharmacology and Experimental Therapeutics 296 (2), 235-242, 2001 | 1232 | 2001 |
| Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite GH Nancollas, R Tang, RJ Phipps, Z Henneman, S Gulde, W Wu, ... Bone 38 (5), 617-627, 2006 | 1130 | 2006 |
| Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases S Boissier, M Ferreras, O Peyruchaud, S Magnetto, FH Ebetino, ... Cancer research 60 (11), 2949-2954, 2000 | 849 | 2000 |
| The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs KL Kavanagh, K Guo, JE Dunford, X Wu, S Knapp, FH Ebetino, ... Proceedings of the National Academy of Sciences 103 (20), 7829-7834, 2006 | 675 | 2006 |
| Bisphosphonates: an update on mechanisms of action and how these relate to clinical efficacy RGG Russell, Z Xia, JE Dunford, UDO Oppermann, A Kwaasi, PA Hulley, ... Annals of the New York Academy of Sciences 1117 (1), 209-257, 2007 | 543 | 2007 |
| The relationship between the chemistry and biological activity of the bisphosphonates FH Ebetino, AML Hogan, S Sun, MK Tsoumpra, X Duan, JT Triffitt, ... Bone 49 (1), 20-33, 2011 | 494 | 2011 |
| Bisphosphonates inhibit prostate and breast carcinoma cell adhesion to unmineralized and mineralized bone extracellular matrices S Boissier, S Magnetto, L Frappart, B Cuzin, FH Ebetino, PD Delmas, ... Cancer research 57 (18), 3890-3894, 1997 | 462 | 1997 |
| Heterocycle‐containing bisphosphonates cause apoptosis and inhibit bone resorption by preventing protein prenylation: Evidence from structure‐activity relationships in J774 … SP Luckman, FP Coxon, FH Ebetino, RGG Russell, MJ Rogers Journal of Bone and Mineral Research 13 (11), 1668-1678, 1998 | 365 | 1998 |
| Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption MM McDonald, WH Khoo, PY Ng, Y Xiao, J Zamerli, P Thatcher, W Kyaw, ... Cell 184 (5), 1330-1347. e13, 2021 | 356 | 2021 |
| Bisphosphonates and cancer-induced bone disease: beyond their antiresorptive activity P Clézardin, FH Ebetino, PGJ Fournier Cancer research 65 (12), 4971-4974, 2005 | 304 | 2005 |
| Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and non-resorbing cells FP Coxon, K Thompson, AJ Roelofs, FH Ebetino, MJ Rogers Bone 42 (5), 848-860, 2008 | 292 | 2008 |
| Differentiating the mechanisms of antiresorptive action of nitrogen containing bisphosphonates ER Van Beek, LH Cohen, IM Leroy, FH Ebetino, C Löwik, SE Papapoulos Bone 33 (5), 805-811, 2003 | 278 | 2003 |
| Inhibition of protein prenylation by bisphosphonates causes sustained activation of Rac, Cdc42, and Rho GTPases JE Dunford, MJ Rogers, FH Ebetino, RJ Phipps, FP Coxon Journal of bone and mineral research 21 (5), 684-694, 2006 | 245 | 2006 |
| Pharmacology of bisphosphonates S Cremers, MT Drake, FH Ebetino, JP Bilezikian, RGG Russell British journal of clinical pharmacology 85 (6), 1052-1062, 2019 | 244 | 2019 |
| Identification of a novel phosphonocarboxylate inhibitor of Rab geranylgeranyl transferase that specifically prevents Rab prenylation in osteoclasts and macrophages FP Coxon, MH Helfrich, B Larijani, M Muzylak, JE Dunford, D Marshall, ... Journal of Biological Chemistry 276 (51), 48213-48222, 2001 | 209 | 2001 |
| Structure–activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate … JE Dunford, AA Kwaasi, MJ Rogers, BL Barnett, FH Ebetino, RGG Russell, ... Journal of medicinal chemistry 51 (7), 2187-2195, 2008 | 197 | 2008 |
| Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivo AJ Roelofs, FP Coxon, FH Ebetino, MW Lundy, ZJ Henneman, ... Journal of Bone and Mineral Research 25 (3), 606-616, 2010 | 196 | 2010 |
| Antiresorptive dose-response relationships across three generations of bisphosphonates. WK Sietsema, FH Ebetino, AM Salvagno, JA Bevan Drugs under experimental and clinical research 15 (9), 389-396, 1989 | 192 | 1989 |
| Photoaffinity labeling of the Ah receptor. A Poland, E Glover, FH Ebetino, AS Kende Journal of Biological Chemistry 261 (14), 6352-6365, 1986 | 175 | 1986 |