Articles with public access mandates - Paul DaviesLearn more
Not available anywhere: 1
Passive immunotherapy for tau pathology
P Davies
Developing Therapeutics for Alzheimer's Disease, 371-384, 2016
Mandates: US National Institutes of Health
Available somewhere: 21
Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases
M Steger, F Tonelli, G Ito, P Davies, M Trost, M Vetter, S Wachter, ...
elife 5, e12813, 2016
Mandates: Swiss National Science Foundation, US National Institutes of Health, UK …
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), eabe9403, 2020
Mandates: US National Science Foundation, Bill & Melinda Gates Foundation, US …
Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2
X Deng, N Dzamko, A Prescott, P Davies, Q Liu, Q Yang, JD Lee, ...
Nature chemical biology 7 (4), 203-205, 2011
Mandates: US National Institutes of Health
Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III …
R Bago, N Malik, MJ Munson, AR Prescott, P Davies, E Sommer, N Shpiro, ...
Biochemical Journal 463 (3), 413-427, 2014
Mandates: UK Medical Research Council, Wellcome Trust
Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice
M Yue, KM Hinkle, P Davies, E Trushina, FC Fiesel, TA Christenson, ...
Neurobiology of disease 78, 172-195, 2015
Mandates: US National Institutes of Health
A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research
SJ Rihn, A Merits, S Bakshi, ML Turnbull, A Wickenhagen, AJT Alexander, ...
PLoS biology 19 (2), e3001091, 2021
Mandates: Bill & Melinda Gates Foundation, National Health and Medical Research …
LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages
A Härtlova, S Herbst, J Peltier, A Rodgers, O Bilkei‐Gorzo, A Fearns, ...
The EMBO journal 37 (12), e98694, 2018
Mandates: Versus Arthritis, UK, Cancer Research UK, UK Medical Research Council …
Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase
P Lis, S Burel, M Steger, M Mann, F Brown, F Diez, F Tonelli, JL Holton, ...
Biochemical Journal 475 (1), 1-22, 2018
Mandates: UK Medical Research Council, Parkinson's UK
The cellular prion protein traps Alzheimer's Aβ in an oligomeric form and disassembles amyloid fibers
ND Younan, CJ Sarell, P Davies, DR Brown, JH Viles
The FASEB Journal 27 (5), 1847, 2013
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Medical …
Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies
P Davies, KM Hinkle, NN Sukar, B Sepulveda, R Mesias, G Serrano, ...
Biochemical Journal 453 (1), 101-113, 2013
Mandates: US National Institutes of Health, UK Medical Research Council, Wellcome Trust
Early onset prion disease from octarepeat expansion correlates with copper binding properties
DJ Stevens, ED Walter, A Rodríguez, D Draper, P Davies, DR Brown, ...
PLoS pathogens 5 (4), e1000390, 2009
Mandates: US National Institutes of Health
Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies
LA Armstrong, SM Lange, V Dee Cesare, SP Matthews, RS Nirujogi, ...
PloS one 16 (7), e0253364, 2021
Mandates: European Molecular Biology Laboratory, UK Medical Research Council, European …
Photoactivatable prodrugs of antimelanoma agent vemurafenib
R Horbert, B Pinchuk, P Davies, D Alessi, C Peifer
ACS chemical biology 10 (9), 2099-2107, 2015
Mandates: German Research Foundation, UK Medical Research Council
Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating …
VP Houde, MS Ritorto, R Gourlay, J Varghese, P Davies, N Shpiro, ...
Biochemical Journal 458 (1), 41-56, 2014
Mandates: UK Medical Research Council, Wellcome Trust
Functional kinomics establishes a critical node of volume-sensitive cation-Cl− cotransporter regulation in the mammalian brain
J Zhang, G Gao, G Begum, J Wang, AR Khanna, BE Shmukler, ...
Scientific reports 6 (1), 35986, 2016
Mandates: US National Institutes of Health, US Department of Veterans Affairs, UK …
High-throughput matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry–based deubiquitylating enzyme assay for drug discovery
V De Cesare, J Moran, R Traynor, A Knebel, MS Ritorto, M Trost, ...
Nature Protocols 15 (12), 4034-4057, 2020
Mandates: UK Medical Research Council
CDK 1 and CDK 2 regulate NICD 1 turnover and the periodicity of the segmentation clock
FA Carrieri, PJ Murray, D Ditsova, MA Ferris, P Davies, JK Dale
EMBO reports 20 (7), e46436, 2019
Mandates: UK Medical Research Council, Wellcome Trust
S-acylation stabilizes ligand-induced receptor kinase complex formation during plant pattern-triggered immune signaling
CH Hurst, D Turnbull, K Xhelilaj, S Myles, RL Pflughaupt, M Kopischke, ...
Current Biology 33 (8), 1588-1596. e6, 2023
Mandates: German Research Foundation, European Molecular Biology Laboratory, UK …
Development of a highly potent and selective degrader of LRRK2
JM Hatcher, M Zwirek, AR Sarhan, PS Vatsan, F Tonelli, DR Alessi, ...
Bioorganic & Medicinal Chemistry Letters 94, 129449, 2023
Mandates: US National Institutes of Health, UK Medical Research Council, Michael J Fox …
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