The influenza virus polymerase complex: an update on its structure, functions, and significance for antiviral drug design A Stevaert, L Naesens Medicinal research reviews 36 (6), 1127-1173, 2016 | 183 | 2016 |
The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways M Laporte, V Raeymaekers, R Van Berwaer, J Vandeput, ... PLoS pathogens 17 (4), e1009500, 2021 | 137 | 2021 |
Antiviral therapies on the horizon for influenza L Naesens, A Stevaert, E Vanderlinden Current opinion in pharmacology 30, 106-115, 2016 | 101 | 2016 |
Mutational analysis of the binding pockets of the diketo acid inhibitor L-742,001 in the influenza virus PA endonuclease A Stevaert, R Dallocchio, A Dessì, N Pala, D Rogolino, M Sechi, ... Journal of virology 87 (19), 10524-10538, 2013 | 83 | 2013 |
Synthesis and biological evaluation of pyrimidine nucleoside monophosphate prodrugs targeted against influenza virus S Meneghesso, E Vanderlinden, A Stevaert, C McGuigan, J Balzarini, ... Antiviral research 94 (1), 35-43, 2012 | 74 | 2012 |
Investigation of the salicylaldehyde thiosemicarbazone scaffold for inhibition of influenza virus PA endonuclease D Rogolino, A Bacchi, L De Luca, G Rispoli, M Sechi, A Stevaert, ... JBIC Journal of Biological Inorganic Chemistry 20, 1109-1121, 2015 | 66 | 2015 |
A versatile salicyl hydrazonic ligand and its metal complexes as antiviral agents D Rogolino, M Carcelli, A Bacchi, C Compari, L Contardi, E Fisicaro, ... Journal of Inorganic Biochemistry 150, 9-17, 2015 | 66 | 2015 |
N-acylhydrazone inhibitors of influenza virus PA endonuclease with versatile metal binding modes M Carcelli, D Rogolino, A Gatti, L De Luca, M Sechi, G Kumar, SW White, ... Scientific reports 6 (1), 31500, 2016 | 61 | 2016 |
Metal-chelating 2-hydroxyphenyl amide pharmacophore for inhibition of influenza virus endonuclease M Carcelli, D Rogolino, A Bacchi, G Rispoli, E Fisicaro, C Compari, ... Molecular pharmaceutics 11 (1), 304-316, 2014 | 53 | 2014 |
Hemagglutinin cleavability, acid stability, and temperature dependence optimize influenza B virus for replication in human airways M Laporte, A Stevaert, V Raeymaekers, T Boogaerts, I Nehlmeier, W Chiu, ... Journal of Virology 94 (1), 10.1128/jvi. 01430-19, 2019 | 51 | 2019 |
Influenza virus entry via the GM3 ganglioside-mediated platelet-derived growth factor receptor β signalling pathway P Vrijens, S Noppen, T Boogaerts, E Vanstreels, R Ronca, P Chiodelli, ... Journal of General Virology 100 (4), 583-601, 2019 | 44 | 2019 |
Chlorogenic compounds from coffee beans exert activity against respiratory viruses V Sinisi, A Stevaert, F Berti, C Forzato, F Benedetti, L Navarini, A Camps, ... Planta Medica 83 (07), 615-623, 2017 | 43 | 2017 |
Virtual screening and biological validation of novel influenza virus PA endonuclease inhibitors N Pala, A Stevaert, R Dallocchio, A Dessì, D Rogolino, M Carcelli, ... ACS Medicinal Chemistry Letters 6 (8), 866-871, 2015 | 43 | 2015 |
An integrated biological approach to guide the development of metal-chelating inhibitors of influenza virus PA endonuclease A Stevaert, S Nurra, N Pala, M Carcelli, D Rogolino, C Shepard, ... Molecular pharmacology 87 (2), 323-337, 2015 | 41 | 2015 |
Betulonic acid derivatives interfering with human coronavirus 229E replication via the nsp15 endoribonuclease A Stevaert, B Krasniqi, B Van Loy, T Nguyen, J Thomas, J Vandeput, ... Journal of medicinal chemistry 64 (9), 5632-5644, 2021 | 36 | 2021 |
Novel indole–flutimide heterocycles with activity against influenza PA endonuclease and hepatitis C virus G Zoidis, E Giannakopoulou, A Stevaert, E Frakolaki, V Myrianthopoulos, ... MedChemComm 7 (3), 447-456, 2016 | 28 | 2016 |
Structure-activity relationship studies of lipophilic teicoplanin pseudoaglycon derivatives as new anti-influenza virus agents Z Szűcs, V Kelemen, S Le Thai, M Csávás, E Rőth, G Batta, A Stevaert, ... European Journal of Medicinal Chemistry 157, 1017-1030, 2018 | 27 | 2018 |
Synthesis and anti‐coronavirus activity of a series of 1‐thia‐4‐azaspiro [4.5] decan‐3‐one derivatives ÇB Apaydın, N Cesur, A Stevaert, L Naesens, Z Cesur Archiv der Pharmazie 352 (6), 1800330, 2019 | 25 | 2019 |
Reprogramming of the antibacterial drug vancomycin results in potent antiviral agents devoid of antibacterial activity Z Szűcs, L Naesens, A Stevaert, E Ostorházi, G Batta, P Herczegh, ... Pharmaceuticals 13 (7), 139, 2020 | 24 | 2020 |
N-benzyl 4, 4-disubstituted piperidines as a potent class of influenza H1N1 virus inhibitors showing a novel mechanism of hemagglutinin fusion peptide interaction S de Castro, T Ginex, E Vanderlinden, M Laporte, A Stevaert, J Cumella, ... European Journal of Medicinal Chemistry 194, 112223, 2020 | 18 | 2020 |