| Clonal evolution of glioblastoma under therapy J Wang, E Cazzato, E Ladewig, V Frattini, DIS Rosenbloom, S Zairis, ... Nature genetics 48 (7), 768-776, 2016 | 757 | 2016 |
| Comparative analysis of the transcriptome across distant species MB Gerstein, J Rozowsky, KK Yan, D Wang, C Cheng, JB Brown, ... Nature 512 (7515), 445-448, 2014 | 343 | 2014 |
| Spatiotemporal genomic architecture informs precision oncology in glioblastoma JK Lee, J Wang, JK Sa, E Ladewig, HO Lee, IH Lee, HJ Kang, ... Nature genetics 49 (4), 594-599, 2017 | 292 | 2017 |
| Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors N Vasan, P Razavi, JL Johnson, H Shao, H Shah, A Antoine, E Ladewig, ... Science 366 (6466), 714-723, 2019 | 264 | 2019 |
| Discovery of hundreds of mirtrons in mouse and human small RNA data E Ladewig, K Okamura, AS Flynt, JO Westholm, EC Lai Genome research 22 (9), 1634-1645, 2012 | 257 | 2012 |
| Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma E Tiacci, E Ladewig, G Schiavoni, A Penson, E Fortini, V Pettirossi, ... Blood, The Journal of the American Society of Hematology 131 (22), 2454-2465, 2018 | 229 | 2018 |
| ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer G Xu, S Chhangawala, E Cocco, P Razavi, Y Cai, JE Otto, L Ferrando, ... Nature genetics 52 (2), 198-207, 2020 | 183 | 2020 |
| Analysis of nearly one thousand mammalian mirtrons reveals novel features of dicer substrates J Wen, E Ladewig, S Shenker, J Mohammed, EC Lai PLoS computational biology 11 (9), e1004441, 2015 | 105 | 2015 |
| FOXA1 mutations reveal distinct chromatin profiles and influence therapeutic response in breast cancer A Arruabarrena-Aristorena, JLV Maag, S Kittane, Y Cai, WR Karthaus, ... Cancer cell 38 (4), 534-550. e9, 2020 | 98 | 2020 |
| Common and distinct patterns of terminal modifications to mirtrons and canonical microRNAs JO Westholm, E Ladewig, K Okamura, N Robine, EC Lai Rna 18 (2), 177-192, 2012 | 91 | 2012 |
| Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma M Fangazio, E Ladewig, K Gomez, L Garcia-Ibanez, R Kumar, ... Proceedings of the National Academy of Sciences 118 (22), e2104504118, 2021 | 78 | 2021 |
| Functional small RNAs are generated from select miRNA hairpin loops in flies and mammals K Okamura, E Ladewig, L Zhou, EC Lai Genes & development 27 (7), 778-792, 2013 | 75 | 2013 |
| Diversity of miRNAs, siRNAs, and piRNAs across 25 Drosophila cell lines J Wen, J Mohammed, D Bortolamiol-Becet, H Tsai, N Robine, ... Genome research 24 (7), 1236-1250, 2014 | 70 | 2014 |
| Nuclear proximity of Mtr4 to RNA exosome restricts DNA mutational asymmetry J Lim, PK Giri, D Kazadi, B Laffleur, W Zhang, V Grinstein, E Pefanis, ... Cell 169 (3), 523-537. e15, 2017 | 68 | 2017 |
| Distinct genomic profile and specific targeted drug responses in adult cerebellar glioblastoma HJ Cho, J Zhao, SW Jung, E Ladewig, DS Kong, YL Suh, Y Lee, D Kim, ... Neuro-oncology 21 (1), 47-58, 2019 | 37 | 2019 |
| Genomic Alterations in PIK3CA-Mutated Breast Cancer Result in mTORC1 Activation and Limit the Sensitivity to PI3Kα Inhibitors Y Cai, G Xu, F Wu, F Michelini, C Chan, X Qu, P Selenica, E Ladewig, ... Cancer research 81 (9), 2470-2480, 2021 | 29 | 2021 |
| Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis MH Do, W Shi, L Ji, E Ladewig, X Zhang, RM Srivastava, KJ Capistrano, ... Immunity 56 (11), 2555-2569. e5, 2023 | 17 | 2023 |
| New recurrently mutated genes in classical hodgkin lymphoma revealed by whole-exome sequencing of microdissected tumor cells E Tiacci, A Penson, G Schiavoni, E Ladewig, E Fortini, Y Wang, ... Blood 128 (22), 1088, 2016 | 15 | 2016 |
| The oncogenic PI3K-induced transcriptomic landscape reveals key functions in splicing and gene expression regulation E Ladewig, F Michelini, K Jhaveri, P Castel, J Carmona, L Fairchild, ... Cancer research 82 (12), 2269-2280, 2022 | 7 | 2022 |
| ERG-driven prostate cancer emerges from basal-luminal hybrid cells. W Feng, E Ladewig, N Salsabeel, H Zhao, YS Lee, A Gopalan, H Luo, ... Biorxiv: the Preprint Server for Biology, 2023 | 2* | 2023 |
Raul RabadanProfessor, Columbia UniversityVerified email at cumc.columbia.edu