Dysfunction of the WT1-MEG3 signaling promotes AML leukemogenesis via p53-dependent and-independent pathways Y Lyu, J Lou, Y Yang, J Feng, Y Hao, S Huang, L Yin, J Xu, D Huang, ... Leukemia 31 (12), 2543-2551, 2017 | 120 | 2017 |
Kynurenine, a tryptophan metabolite that accumulates with age, induces bone loss ME Refaey, ME McGee‐Lawrence, S Fulzele, EJ Kennedy, WB Bollag, ... Journal of Bone and Mineral Research 32 (11), 2182-2193, 2017 | 107 | 2017 |
The senolytic drug navitoclax (ABT-263) causes trabecular bone loss and impaired osteoprogenitor function in aged mice AK Sharma, RL Roberts, RD Benson Jr, JL Pierce, K Yu, MW Hamrick, ... Frontiers in cell and developmental biology 8, 354, 2020 | 99 | 2020 |
SIRT1 in cardiovascular aging XY Luo, SL Qu, ZH Tang, Y Zhang, MH Liu, J Peng, H Tang, KL Yu, ... Clinica Chimica Acta 437, 106-114, 2014 | 88 | 2014 |
Kynurenine, a tryptophan metabolite that increases with age, induces muscle atrophy and lipid peroxidation H Kaiser, K Yu, C Pandya, B Mendhe, CM Isales, ME McGee-Lawrence, ... Oxidative medicine and cellular longevity 2019 (1), 9894238, 2019 | 76 | 2019 |
Mechanical loading disrupts osteocyte plasma membranes which initiates mechanosensation events in bone K Yu, DP Sellman, A Bahraini, ML Hagan, A Elsherbini, KT Vanpelt, ... Journal of Orthopaedic Research® 36 (2), 653-662, 2018 | 49 | 2018 |
Reduced bone formation in males and increased bone resorption in females drive bone loss in hemophilia A mice MN Weitzmann, S Roser-Page, T Vikulina, D Weiss, L Hao, WH Baldwin, ... Blood Advances 3 (3), 288-300, 2019 | 28 | 2019 |
The glucocorticoid receptor in osteoprogenitors regulates bone mass and marrow fat JL Pierce, KH Ding, J Xu, AK Sharma, K Yu, N del Mazo Arbona, ... Journal of Endocrinology 243 (1), 27-42, 2019 | 26 | 2019 |
Decreased pericellular matrix production and selection for enhanced cell membrane repair may impair osteocyte responses to mechanical loading in the aging skeleton ML Hagan, K Yu, J Zhu, BN Vinson, RL Roberts, M Montesinos Cartagena, ... Aging Cell 19 (1), e13056, 2020 | 25 | 2020 |
Kynurenine suppresses osteoblastic cell energetics in vitro and osteoblast numbers in vivo JL Pierce, RL Roberts, K Yu, RK Kendall, H Kaiser, C Davis, MH Johnson, ... Experimental gerontology 130, 110818, 2020 | 24 | 2020 |
Mimicking the effects of spaceflight on bone: Combined effects of disuse and chronic low-dose rate radiation exposure on bone mass in mice K Yu, AH Doherty, PC Genik, SE Gookin, DM Roteliuk, SJ Wojda, ... Life Sciences in Space Research 15, 62-68, 2017 | 23 | 2017 |
The glucocorticoid receptor in osterix‐expressing cells regulates bone mass, bone marrow adipose tissue, and systemic metabolism in female mice during aging JL Pierce, AK Sharma, RL Roberts, K Yu, DL Irsik, V Choudhary, JS Dorn, ... Journal of Bone and Mineral Research 37 (2), 285-302, 2020 | 21 | 2020 |
Inhibition of osteocyte membrane repair activity via dietary vitamin E deprivation impairs osteocyte survival ML Hagan, A Bahraini, JL Pierce, SM Bass, K Yu, R Elsayed, M Elsalanty, ... Calcified tissue international 104, 224-234, 2019 | 15 | 2019 |
Neutralization of CD40 ligand costimulation promotes bone formation and accretion of vertebral bone mass in mice S Roser-Page, T Vikulina, K Yu, ME McGee-Lawrence, MN Weitzmann Rheumatology 57 (6), 1105-1114, 2018 | 12 | 2018 |
Hindlimb immobilization increases IL-1β and Cdkn2a expression in skeletal muscle fibro-adipogenic progenitor cells: a link between senescence and muscle disuse atrophy E Parker, A Khayrullin, A Kent, B Mendhe, KB Youssef El Baradie, K Yu, ... Frontiers in Cell and Developmental Biology 9, 790437, 2022 | 11 | 2022 |
Deletion of protein kinase D1 in osteoprogenitor cells results in decreased osteogenesis in vitro and reduced bone mineral density in vivo WB Bollag, V Choudhary, Q Zhong, KH Ding, J Xu, R Elsayed, K Yu, Y Su, ... Molecular and cellular endocrinology 461, 22-31, 2018 | 11 | 2018 |
Loss of Hdac3 in osteoprogenitors increases bone expression of osteoprotegerin, improving systemic insulin sensitivity ME McGee‐Lawrence, JL Pierce, K Yu, NR Culpepper, EW Bradley, ... Journal of cellular physiology 233 (4), 2671-2680, 2018 | 10 | 2018 |
Monomethylfumarate protects against ovariectomy-related changes in body composition AE Bollag, T Guo, KH Ding, V Choudhary, X Chen, Q Zhong, J Xu, K Yu, ... Journal of Endocrinology 243 (1), 15-26, 2019 | 6 | 2019 |
Orchiectomy sensitizes cortical bone in male mice to the harmful effects of kynurenine H Bensreti, K Yu, DW Alhamad, J Shaver, H Kaiser, R Zhong, ... Bone 173, 116811, 2023 | 4 | 2023 |
Immune reconstitution bone loss exacerbates bone degeneration due to natural aging in a mouse model MN Weitzmann, D Weiss, T Vikulina, S Roser-Page, K Yu, ... The Journal of infectious diseases 226 (1), 38-48, 2022 | 4 | 2022 |