| Skin whitening agents: medicinal chemistry perspective of tyrosinase inhibitors T Pillaiyar, M Manickam, V Namasivayam J Enzyme Inhib Med Chem 32 (1), 403-425, 2017 | 933 | 2017 |
| An Overview of Severe Acute Respiratory Syndrome–Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy T Pillaiyar, M Manickam, V Namasivayam, Y Hayashi, SH Jung Journal of medicinal chemistry 59 (14), 6595-6628, 2016 | 828 | 2016 |
| Recent discovery and development of inhibitors targeting coronaviruses T Pillaiyar, S Meenakshisundaram, M Manickam Drug discovery today 25 (4), 668-688, 2020 | 420 | 2020 |
| Inhibitors of melanogenesis: an updated review T Pillaiyar, V Namasivayam, M Manickam, SH Jung Journal of medicinal chemistry 61 (17), 7395-7418, 2018 | 306 | 2018 |
| Recent development of signaling pathways inhibitors of melanogenesis T Pillaiyar, M Manickam, SH Jung Cellular signalling 40, 99-115, 2017 | 252 | 2017 |
| Downregulation of melanogenesis: Drug discovery and therapeutic options T Pillaiyar, M Manickam, SH Jung Drug Discovery Today 22 (2), 282-298, 2017 | 159 | 2017 |
| Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice C Hess, CT Schoeder, T Pillaiyar, B Madea, CE Müller Forensic Toxicology 34 (2), 329–343, 2016 | 136 | 2016 |
| 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents S Konno, K Kobayashi, M Senda, Y Funai, Y Seki, I Tamai, L Schäkel, ... Journal of medicinal chemistry 65 (4), 2926–2939, 2022 | 132 | 2022 |
| A medicinal chemistry perspective of drug repositioning: Recent advances and challenges in drug discovery T Pillaiyar, S Meenakshisundaram, M Manickam, M Sankaranarayanan European journal of medicinal chemistry 195, 112275, 2020 | 127 | 2020 |
| Targeting the main protease of SARS‐CoV‐2: from the establishment of high throughput screening to the design of tailored inhibitors J Breidenbach, C Lemke, T Pillaiyar, L Schäkel, G Al Hamwi, M Diett, ... Angewandte Chemie International Edition 60 (18), 10423-10429, 2021 | 123 | 2021 |
| Development of potent dipeptide-type SARS-CoV 3CL protease inhibitors with novel P3 scaffolds: design, synthesis, biological evaluation, and docking studies P Thanigaimalai, S Konno, T Yamamoto, Y Koiwai, A Taguchi, ... European journal of medicinal chemistry 68, 372-384, 2013 | 109 | 2013 |
| Diindolylmethane derivatives: potent agonists of the immunostimulatory orphan G protein-coupled receptor GPR84 T Pillaiyar, M Köse, K Sylvester, H Weighardt, D Thimm, G Borges, ... Journal of medicinal chemistry 60 (9), 3636-3655, 2017 | 99 | 2017 |
| Design, synthesis, and biological evaluation of novel dipeptide-type SARS-CoV 3CL protease inhibitors: Structure–activity relationship study P Thanigaimalai, S Konno, T Yamamoto, Y Koiwai, A Taguchi, ... European journal of medicinal chemistry 65, 436-447, 2013 | 83 | 2013 |
| Design and synthesis of new tripeptide-type SARS-CoV 3CL protease inhibitors containing an electrophilic arylketone moiety S Konno, P Thanigaimalai, T Yamamoto, K Nakada, R Kakiuchi, ... Bioorganic & medicinal chemistry 21 (2), 412-424, 2013 | 82 | 2013 |
| Structural requirement (s) of N-phenylthioureas and benzaldehyde thiosemicarbazones as inhibitors of melanogenesis in melanoma B 16 cells P Thanigaimalai, TA Le Hoang, KC Lee, SC Bang, VK Sharma, CY Yun, ... Bioorganic & medicinal chemistry letters 20 (9), 2991-2993, 2010 | 79 | 2010 |
| Inhibitors of melanogenesis: a patent review (2009–2014) T Pillaiyar, M Manickam, SH Jung Expert opinion on therapeutic patents 25 (7), 775-788, 2015 | 76 | 2015 |
| Kinases as potential therapeutic targets for anti-coronaviral therapy T Pillaiyar, S Laufer Journal of Medicinal Chemistry 65 (2), 955-982, 2022 | 63 | 2022 |
| Small-molecule thioesters as SARS-CoV-2 main protease inhibitors: enzyme inhibition, structure–activity relationships, antiviral activity, and X-ray structure determination T Pillaiyar, P Flury, N Krüger, H Su, L Schäkel, E Barbosa Da Silva, ... Journal of Medicinal Chemistry 65 (13), 9376-9395, 2022 | 59 | 2022 |
| General synthesis of unsymmetrical 3, 3′-(aza) diindolylmethane derivatives T Pillaiyar, E Gorska, G Schnakenburg, CE Müller The Journal of Organic Chemistry 83 (17), 9902-9913, 2018 | 48 | 2018 |
| Targeting tyrosinase in hyperpigmentation: Current status, limitations and future promises S Zolghadri, M Beygi, TF Mohammad, M Alijanianzadeh, T Pillaiyar, ... Biochemical pharmacology 212, 115574, 2023 | 47 | 2023 |
Christa E. MüllerUniversity of BonnVerified email at uni-bonn.de
