PA-824 Kills Nonreplicating Mycobacterium tuberculosis by Intracellular NO Release R Singh, U Manjunatha, HIM Boshoff, YH Ha, P Niyomrattanakit, ... Science 322 (5906), 1392-1395, 2008 | 825 | 2008 |
Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs R Singh, V Rao, H Shakila, R Gupta, A Khera, N Dhar, A Singh, A Koul, ... Molecular microbiology 50 (3), 751-762, 2003 | 199 | 2003 |
MazF ribonucleases promote Mycobacterium tuberculosis drug tolerance and virulence in guinea pigs P Tiwari, G Arora, M Singh, S Kidwai, OP Narayan, R Singh Nature communications 6 (1), 6059, 2015 | 167 | 2015 |
MazF ribonucleases promote Mycobacterium tuberculosis drug tolerance and virulence in guinea pigs P Tiwari, G Arora, M Singh, S Kidwai, OP Narayan, R Singh Nature communications 6 (1), 6059, 2015 | 167 | 2015 |
The Three RelE Homologs of Mycobacterium tuberculosis Have Individual, Drug-Specific Effects on Bacterial Antibiotic Tolerance R Singh, CE Barry III, HIM Boshoff Journal of bacteriology 192 (5), 1279-1291, 2010 | 158 | 2010 |
Structure− activity relationships of antitubercular nitroimidazoles. 1. Structural features associated with aerobic and anaerobic activities of 4-and 5-nitroimidazoles P Kim, L Zhang, UH Manjunatha, R Singh, S Patel, J Jiricek, TH Keller, ... Journal of medicinal chemistry 52 (5), 1317-1328, 2009 | 127 | 2009 |
Structure− activity relationships of antitubercular nitroimidazoles. 2. Determinants of aerobic activity and quantitative structure− activity relationships P Kim, S Kang, HI Boshoff, J Jiricek, M Collins, R Singh, UH Manjunatha, ... Journal of medicinal chemistry 52 (5), 1329-1344, 2009 | 109 | 2009 |
Synthesis of novel 1, 2, 3-triazole derivatives of isoniazid and their in vitro and in vivo antimycobacterial activity evaluation D Kumar, G Khare, S Kidwai, AK Tyagi, R Singh, DS Rawat European journal of medicinal chemistry 81, 301-313, 2014 | 107 | 2014 |
Substrate specificity of the deazaflavin‐dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic … M Gurumurthy, T Mukherjee, CS Dowd, R Singh, P Niyomrattanakit, ... The FEBS journal 279 (1), 113-125, 2012 | 106 | 2012 |
Polyphosphate deficiency in Mycobacterium tuberculosis is associated with enhanced drug susceptibility and impaired growth in guinea pigs R Singh, M Singh, G Arora, S Kumar, P Tiwari, S Kidwai Journal of bacteriology 195 (12), 2839-2851, 2013 | 99 | 2013 |
Phosphoprotein phosphatase of Mycobacterium tuberculosis dephosphorylates serine–threonine kinases PknA and PknB P Chopra, B Singh, R Singh, R Vohra, A Koul, LS Meena, H Koduri, ... Biochemical and biophysical research communications 311 (1), 112-120, 2003 | 88 | 2003 |
HupB, a Nucleoid-Associated Protein of Mycobacterium tuberculosis, Is Modified by Serine/Threonine Protein Kinases In Vivo M Gupta, A Sajid, K Sharma, S Ghosh, G Arora, R Singh, V Nagaraja, ... Journal of bacteriology 196 (14), 2646-2657, 2014 | 78 | 2014 |
Enhanced and enduring protection against tuberculosis by recombinant BCG-Ag85C and its association with modulation of cytokine profile in lung R Jain, B Dey, N Dhar, V Rao, R Singh, UD Gupta, VM Katoch, ... PLoS One 3 (12), e3869, 2008 | 75 | 2008 |
Elicitation of efficient, protective immune responses by using DNA vaccines against tuberculosis A Khera, R Singh, H Shakila, V Rao, N Dhar, PR Narayanan, ... Vaccine 23 (48-49), 5655-5665, 2005 | 69 | 2005 |
Anti-methicillin resistant Staphylococcus aureus activity, synergism with oxacillin and molecular docking studies of metronidazole-triazole hybrids B Negi, D Kumar, W Kumbukgolla, S Jayaweera, P Ponnan, R Singh, ... European journal of medicinal chemistry 115, 426-437, 2016 | 60 | 2016 |
Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment SK Malladi, R Singh, S Pandey, S Gayathri, K Kanjo, S Ahmed, MS Khan, ... Journal of Biological Chemistry 296, 2021 | 53 | 2021 |
Dual mechanism of action of 5-nitro-1, 10-phenanthroline against Mycobacterium tuberculosis S Kidwai, CY Park, S Mawatwal, P Tiwari, MG Jung, TP Gosain, P Kumar, ... Antimicrobial agents and chemotherapy 61 (11), 10.1128/aac. 00969-17, 2017 | 50 | 2017 |
Structural, functional and biological insights into the role of Mycobacterium tuberculosis VapBC11 toxin–antitoxin system: targeting a tRNase to tackle … A Deep, P Tiwari, S Agarwal, S Kaundal, S Kidwai, R Singh, KG Thakur Nucleic acids research 46 (21), 11639-11655, 2018 | 48 | 2018 |
Structure–Activity Relationships of Antitubercular Nitroimidazoles. 3. Exploration of the Linker and Lipophilic Tail of ((S)-2-Nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3 … J Cherian, I Choi, A Nayyar, UH Manjunatha, T Mukherjee, YS Lee, ... Journal of medicinal chemistry 54 (16), 5639-5659, 2011 | 47 | 2011 |
Establishing Virulence Associated Polyphosphate Kinase 2 as a drug target for Mycobacterium tuberculosis M Singh, P Tiwari, G Arora, S Agarwal, S Kidwai, R Singh Scientific reports 6 (1), 26900, 2016 | 46 | 2016 |