| Genetic drivers of heterogeneity in type 2 diabetes pathophysiology K Suzuki, K Hatzikotoulas, L Southam, HJ Taylor, X Yin, KM Lorenz, ... Nature 627 (8003), 347-357, 2024 | 122 | 2024 |
| ATAC-Seq Reveals an Isl1 Enhancer That Regulates Sinoatrial Node Development and Function G Galang, R Mandla, H Ruan, C Jung, T Sinha, NR Stone, RS Wu, ... Circulation research 127 (12), 1502-1518, 2020 | 56 | 2020 |
| A second update on mapping the human genetic architecture of COVID-19 M Kanai, SJ Andrews, M Cordioli, C Stevens, BM Neale, M Daly, A Ganna, ... Nature 621 (7977), E7-E26, 2023 | 50 | 2023 |
| NR4A family members regulate T cell tolerance to preserve immune homeostasis and suppress autoimmunity R Hiwa, HV Nielsen, JL Mueller, R Mandla, J Zikherman JCI insight 6 (17), 2021 | 29 | 2021 |
| Multi-ancestry polygenic mechanisms of type 2 diabetes K Smith, AJ Deutsch, C McGrail, H Kim, S Hsu, A Huerta-Chagoya, ... Nature medicine 30 (4), 1065-1074, 2024 | 26 | 2024 |
| Calibrated prediction intervals for polygenic scores across diverse contexts K Hou, Z Xu, Y Ding, R Mandla, Z Shi, K Boulier, A Harpak, B Pasaniuc Nature Genetics, 1-11, 2024 | 22 | 2024 |
| Multi-ancestry genome-wide study in> 2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications K Suzuki, K Hatzikotoulas, L Southam, HJ Taylor, X Yin, KM Lorenz, ... medRxiv, 2023 | 22 | 2023 |
| Transcriptional and epigenetic landscape of cardiac pacemaker cells: insights into cellular specialization in the sinoatrial node R Mandla, C Jung, V Vedantham Frontiers in physiology 12, 712666, 2021 | 19 | 2021 |
| The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes A Huerta-Chagoya, P Schroeder, R Mandla, AJ Deutsch, W Zhu, L Petty, ... Diabetologia 66 (7), 1273-1288, 2023 | 15 | 2023 |
| Type 2 diabetes polygenic score predicts the risk of glucocorticoid-induced hyperglycemia in patients without diabetes AJ Deutsch, PH Schroeder, R Mandla, S Kang, F Erenler, JM Mercader, ... Diabetes Care 46 (8), 1541-1545, 2023 | 11 | 2023 |
| Whole genome association testing in 333,100 individuals across three biobanks identifies rare non-coding single variant and genomic aggregate associations with height G Hawkes, RN Beaumont, Z Li, R Mandla, X Li, CM Albert, DK Arnett, ... bioRxiv, 2023.11. 19.566520, 2023 | 8 | 2023 |
| Rare variant analyses in 51,256 type 2 diabetes cases and 370,487 controls reveal the pathogenicity spectrum of monogenic diabetes genes A Huerta-Chagoya, P Schroeder, R Mandla, J Li, L Morris, M Vora, ... Nature genetics, 1-10, 2024 | 6 | 2024 |
| Polygenic scores for longitudinal prediction of incident type 2 diabetes in an ancestrally and medically diverse primary care physician network: a patient cohort study R Mandla, P Schroeder, B Porneala, JC Florez, JB Meigs, JM Mercader, ... Genome Medicine 16 (1), 63, 2024 | 4 | 2024 |
| Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height G Hawkes, RN Beaumont, Z Li, R Mandla, X Li, CM Albert, DK Arnett, ... Nature Communications 15 (1), 8549, 2024 | 3 | 2024 |
| Rare variant association analysis in 51,256 type 2 diabetes cases and 370,487 controls informs the spectrum of pathogenicity of monogenic diabetes genes P Schroeder, R Mandla, A Huerta-Chagoya, A Alkanak, D Nagy, ... medRxiv, 2023 | 3 | 2023 |
| Multi-ancestry polygenic mechanisms of type 2 diabetes elucidate disease processes and clinical heterogeneity K Smith, AJ Deutsch, C McGrail, H Kim, S Hsu, R Mandla, PH Schroeder, ... medRxiv, 2023 | 3 | 2023 |
| All of Us diversity and scale improve polygenic prediction contextually with greatest improvements for under-represented populations K Tsuo, Z Shi, T Ge, R Mandla, K Hou, Y Ding, B Pasaniuc, Y Wang, ... BioRxiv, 2024 | 2 | 2024 |
| Algorithms for the identification of prevalent diabetes in the All of Us Research Program validated using polygenic scores–a new resource for diabetes precision medicine L Szczerbinski, R Mandla, P Schroeder, BC Porneala, JH Li, JC Florez, ... medRxiv, 2023 | 2 | 2023 |
| Hemoglobin A1c Genetics and Disparities in Risk of Diabetic Retinopathy in Individuals of Genetically Inferred African American/African British and European … R Mandla, PH Schroeder, JC Florez, JM Mercader, A Leong Diabetes Care 47 (10), 1731-1739, 2024 | 1 | 2024 |
| Multi-omics characterization of type 2 diabetes associated genetic variation R Mandla, K Lorenz, X Yin, O Bocher, A Huerta-Chagoya, AL Arruda, ... medRxiv, 2024 | 1 | 2024 |
