| Matrix-embedded cells control osteoclast formation J Xiong, M Onal, RL Jilka, RS Weinstein, SC Manolagas, CA O'Brien Nature medicine 17 (10), 1235-1241, 2011 | 1486 | 2011 |
| Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone J Xiong, M Piemontese, M Onal, J Campbell, JJ Goellner, V Dusevich, ... PloS one 10 (9), e0138189, 2015 | 367 | 2015 |
| Osteocyte RANKL: new insights into the control of bone remodeling J Xiong, CA O'Brien Journal of Bone and Mineral Research 27 (3), 499-505, 2012 | 366 | 2012 |
| Estrogen receptor-α signaling in osteoblast progenitors stimulates cortical bone accrual M Almeida, S Iyer, M Martin-Millan, SM Bartell, L Han, E Ambrogini, ... The Journal of clinical investigation 123 (1), 394-404, 2013 | 302 | 2013 |
| Stimulation of Piezo1 by mechanical signals promotes bone anabolism X Li, L Han, I Nookaew, E Mannen, MJ Silva, M Almeida, J Xiong Elife 8, e49631, 2019 | 289 | 2019 |
| Receptor Activator of Nuclear Factor κB Ligand (RANKL) Protein Expression by B Lymphocytes Contributes to Ovariectomy-induced Bone Loss M Onal, J Xiong, X Chen, JD Thostenson, M Almeida, SC Manolagas, ... Journal of Biological Chemistry 287 (35), 29851-29860, 2012 | 261 | 2012 |
| Suppression of Autophagy in Osteocytes Mimics Skeletal Aging M Onal, M Piemontese, J Xiong, Y Wang, L Han, S Ye, M Komatsu, ... Journal of Biological Chemistry 288 (24), 17432-17440, 2013 | 223 | 2013 |
| Old age causes de novo intracortical bone remodeling and porosity in mice M Piemontese, M Almeida, AG Robling, HN Kim, J Xiong, JD Thostenson, ... JCI insight 2 (17), 2017 | 170 | 2017 |
| Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss J Xiong, K Cawley, M Piemontese, Y Fujiwara, H Zhao, JJ Goellner, ... Nature Communications 9 (1), 2909, 2018 | 146 | 2018 |
| Osteocyte-derived RANKL is a critical mediator of the increased bone resorption caused by dietary calcium deficiency J Xiong, M Piemontese, JD Thostenson, RS Weinstein, SC Manolagas, ... Bone 66, 146-154, 2014 | 141 | 2014 |
| Cortical bone loss caused by glucocorticoid excess requires RANKL production by osteocytes and is associated with reduced OPG expression in mice M Piemontese, J Xiong, Y Fujiwara, JD Thostenson, CA O'Brien American Journal of Physiology-Endocrinology and Metabolism 311 (3), E587-E593, 2016 | 123 | 2016 |
| The YAP/TAZ transcriptional co-activators have opposing effects at different stages of osteoblast differentiation J Xiong, M Almeida, CA O'Brien Bone 112, 1-9, 2018 | 113 | 2018 |
| RANKL (Receptor Activator of NFκB Ligand) produced by osteocytes is required for the increase in B cells and bone loss caused by estrogen deficiency in mice Y Fujiwara, M Piemontese, Y Liu, JD Thostenson, J Xiong, CA O'Brien Journal of Biological Chemistry 291 (48), 24838-24850, 2016 | 109 | 2016 |
| Low bone mass and changes in the osteocyte network in mice lacking autophagy in the osteoblast lineage M Piemontese, M Onal, J Xiong, L Han, JD Thostenson, M Almeida, ... Scientific reports 6, 24262, 2016 | 101 | 2016 |
| Local Production of Osteoprotegerin by Osteoblasts Suppresses Bone Resorption KM Cawley, NC Bustamante-Gomez, AG Guha, RS MacLeod, J Xiong, ... Cell reports 32 (10), 108052, 2020 | 93 | 2020 |
| Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence HN Kim, J Xiong, RS MacLeod, S Iyer, Y Fujiwara, KM Cawley, L Han, ... JCI insight 5 (19), 2020 | 84 | 2020 |
| Suppression of autophagy in osteocytes does not modify the adverse effects of glucocorticoids on cortical bone M Piemontese, M Onal, J Xiong, Y Wang, M Almeida, JD Thostenson, ... Bone 75, 18-26, 2015 | 60 | 2015 |
| HPV16E7 mediates HADC chromatin repression and downregulation of MHC class I genes in HPV16 tumorigenic cells through interaction with an MHC class I promoter H Li, X Ou, J Xiong, T Wang Biochemical and biophysical research communications 349 (4), 1315-1321, 2006 | 53 | 2006 |
| New advances in osteocyte mechanotransduction X Li, J Kordsmeier, J Xiong Current Osteoporosis Reports 19 (1), 101-106, 2021 | 34 | 2021 |
| The RANKL distal control region is required for the increase in RANKL expression, but not the bone loss, associated with hyperparathyroidism or lactation in adult mice M Onal, C Galli, Q Fu, J Xiong, RS Weinstein, SC Manolagas, CA O'Brien Molecular Endocrinology 26 (2), 341-348, 2011 | 29 | 2011 |
Charles A. O'BrienUniversity of Arkansas for Medical SciencesVerified email at uams.edu