Environment drives selection and function of enhancers controlling tissue-specific macrophage identities D Gosselin, VM Link, CE Romanoski, GJ Fonseca, DZ Eichenfield, ... Cell 159 (6), 1327-1340, 2014 | 1404 | 2014 |
MAIT cells are imprinted by the microbiota in early life and promote tissue repair MG Constantinides, VM Link, S Tamoutounour, AC Wong, ... Science 366 (6464), eaax6624, 2019 | 478 | 2019 |
Sympathetic neuron–associated macrophages contribute to obesity by importing and metabolizing norepinephrine RM Pirzgalska, E Seixas, JS Seidman, VM Link, NM Sánchez, I Mahú, ... Nature medicine 23 (11), 1309-1318, 2017 | 455 | 2017 |
Niche-specific reprogramming of epigenetic landscapes drives myeloid cell diversity in nonalcoholic steatohepatitis JS Seidman, TD Troutman, M Sakai, A Gola, NJ Spann, H Bennett, ... Immunity 52 (6), 1057-1074. e7, 2020 | 357 | 2020 |
Liver-derived signals sequentially reprogram myeloid enhancers to initiate and maintain Kupffer cell identity M Sakai, TD Troutman, JS Seidman, Z Ouyang, NJ Spann, Y Abe, KM Ego, ... Immunity 51 (4), 655-670. e8, 2019 | 330 | 2019 |
SREBP1 contributes to resolution of pro-inflammatory TLR4 signaling by reprogramming fatty acid metabolism Y Oishi, NJ Spann, VM Link, ED Muse, T Strid, C Edillor, MJ Kolar, ... Cell metabolism 25 (2), 412-427, 2017 | 326 | 2017 |
The bone marrow protects and optimizes immunological memory during dietary restriction N Collins, SJ Han, M Enamorado, VM Link, B Huang, EA Moseman, ... Cell 178 (5), 1088-1101. e15, 2019 | 241 | 2019 |
Infection trains the host for microbiota-enhanced resistance to pathogens A Stacy, V Andrade-Oliveira, JA McCulloch, B Hild, JH Oh, ... Cell 184 (3), 615-627. e17, 2021 | 206 | 2021 |
Analysis of genetically diverse macrophages reveals local and domain-wide mechanisms that control transcription factor binding and function VM Link, SH Duttke, HB Chun, IR Holtman, E Westin, MA Hoeksema, ... Cell 173 (7), 1796-1809. e17, 2018 | 194 | 2018 |
Prenatal maternal infection promotes tissue-specific immunity and inflammation in offspring AI Lim, T McFadden, VM Link, SJ Han, RM Karlsson, A Stacy, TK Farley, ... Science 373 (6558), eabf3002, 2021 | 166 | 2021 |
Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota DS Lima-Junior, SR Krishnamurthy, N Bouladoux, N Collins, SJ Han, ... Cell 184 (14), 3794-3811. e19, 2021 | 142 | 2021 |
Immunity to commensal skin fungi promotes psoriasiform skin inflammation C Hurabielle, VM Link, N Bouladoux, SJ Han, ED Merrill, YL Lightfoot, ... Proceedings of the National Academy of Sciences 117 (28), 16465-16474, 2020 | 92 | 2020 |
Keratinocyte-intrinsic MHCII expression controls microbiota-induced Th1 cell responses S Tamoutounour, SJ Han, J Deckers, MG Constantinides, C Hurabielle, ... Proceedings of the National Academy of Sciences 116 (47), 23643-23652, 2019 | 80 | 2019 |
Immunity to the microbiota promotes sensory neuron regeneration M Enamorado, W Kulalert, SJ Han, I Rao, J Delaleu, VM Link, D Yong, ... Cell 186 (3), 607-620. e17, 2023 | 78 | 2023 |
Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages DZ Eichenfield, TD Troutman, VM Link, MT Lam, H Cho, D Gosselin, ... elife 5, e13024, 2016 | 75 | 2016 |
Transcriptomic and epigenetic mechanisms underlying myeloid diversity in the lung E Sajti, VM Link, Z Ouyang, NJ Spann, E Westin, CE Romanoski, ... Nature immunology 21 (2), 221-231, 2020 | 73 | 2020 |
Diverse motif ensembles specify non-redundant DNA binding activities of AP-1 family members in macrophages GJ Fonseca, J Tao, EM Westin, SH Duttke, NJ Spann, T Strid, Z Shen, ... Nature communications 10 (1), 414, 2019 | 66 | 2019 |
Mucosal-associated invariant T cells restrict reactive oxidative damage and preserve meningeal barrier integrity and cognitive function Y Zhang, JT Bailey, E Xu, K Singh, M Lavaert, VM Link, S D’Souza, ... Nature immunology 23 (12), 1714-1725, 2022 | 59 | 2022 |
Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells Y Higashijima, Y Matsui, T Shimamura, R Nakaki, N Nagai, S Tsutsumi, ... The EMBO Journal 39 (7), e103949, 2020 | 51 | 2020 |
Genetic variation in type 1 diabetes reconfigures the 3D chromatin organization of T cells and alters gene expression M Fasolino, N Goldman, W Wang, B Cattau, Y Zhou, J Petrovic, VM Link, ... Immunity 52 (2), 257-274. e11, 2020 | 51 | 2020 |