| A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis AL Nishimura, M Mitne-Neto, HCA Silva, A Richieri-Costa, S Middleton, ... The American Journal of Human Genetics 75 (5), 822-831, 2004 | 1251 | 2004 |
| Synthesis, structure, and metalation of two new highly porous zirconium metal–organic frameworks W Morris, B Volosskiy, S Demir, F Gándara, PL McGrier, H Furukawa, ... Inorganic chemistry 51 (12), 6443-6445, 2012 | 937 | 2012 |
| Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis M Strong, MR Sawaya, S Wang, M Phillips, D Cascio, D Eisenberg Proceedings of the National Academy of Sciences 103 (21), 8060-8065, 2006 | 848 | 2006 |
| Structure of the toxic core of α-synuclein from invisible crystals JA Rodriguez, MI Ivanova, MR Sawaya, D Cascio, FE Reyes, D Shi, ... Nature 525 (7570), 486-490, 2015 | 661 | 2015 |
| The crystal structure of mouse VDAC1 at 2.3 Å resolution reveals mechanistic insights into metabolite gating R Ujwal, D Cascio, JP Colletier, S Faham, J Zhang, L Toro, P Ping, ... Proceedings of the National Academy of Sciences 105 (46), 17742-17747, 2008 | 640 | 2008 |
| Atomic view of a toxic amyloid small oligomer A Laganowsky, C Liu, MR Sawaya, JP Whitelegge, J Park, M Zhao, ... Science 335 (6073), 1228-1231, 2012 | 621 | 2012 |
| The crystal structure of a sodium galactose transporter reveals mechanistic insights into Na+/sugar symport S Faham, A Watanabe, GM Besserer, D Cascio, A Specht, BA Hirayama, ... Science 321 (5890), 810-814, 2008 | 613 | 2008 |
| Accurate design of megadalton-scale two-component icosahedral protein complexes JB Bale, S Gonen, Y Liu, W Sheffler, D Ellis, C Thomas, D Cascio, ... Science 353 (6297), 389-394, 2016 | 596 | 2016 |
| Molecular basis for amyloid-β polymorphism JP Colletier, A Laganowsky, M Landau, M Zhao, AB Soriaga, ... Proceedings of the National Academy of Sciences 108 (41), 16938-16943, 2011 | 460 | 2011 |
| Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks MP Hughes, MR Sawaya, DR Boyer, L Goldschmidt, JA Rodriguez, ... Science 359 (6376), 698-701, 2018 | 451 | 2018 |
| Crystal structure of a synthetic triple-stranded α-helical bundle B Lovejoy, S Choe, D Cascio, DK McRorie, WF DeGrado, D Eisenberg Science 259 (5099), 1288-1293, 1993 | 409 | 1993 |
| Atomic structure of the cross‐β spine of islet amyloid polypeptide (amylin) JJW Wiltzius, SA Sievers, MR Sawaya, D Cascio, D Popov, C Riekel, ... Protein Science 17 (9), 1467-1474, 2008 | 404 | 2008 |
| Engineering an allosteric transcription factor to respond to new ligands ND Taylor, AS Garruss, R Moretti, S Chan, MA Arbing, D Cascio, ... Nature methods 13 (2), 177-183, 2016 | 337 | 2016 |
| Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function A Laganowsky, JLP Benesch, M Landau, L Ding, MR Sawaya, D Cascio, ... Protein science 19 (5), 1031-1043, 2010 | 332 | 2010 |
| Structure of a 16-nm cage designed by using protein oligomers YT Lai, D Cascio, TO Yeates Science 336 (6085), 1129-1129, 2012 | 326 | 2012 |
| Structure-based inhibitors of tau aggregation PM Seidler, DR Boyer, JA Rodriguez, MR Sawaya, D Cascio, K Murray, ... Nature chemistry 10 (2), 170-176, 2018 | 319 | 2018 |
| The crystal structure of a cyanobacterial water-soluble carotenoid binding protein CA Kerfeld, MR Sawaya, V Brahmandam, D Cascio, KK Ho, ... Structure 11 (1), 55-65, 2003 | 319 | 2003 |
| Crystal structures of spin labeled T4 lysozyme mutants: implications for the interpretation of EPR spectra in terms of structure R Langen, KJ Oh, D Cascio, WL Hubbell Biochemistry 39 (29), 8396-8405, 2000 | 318 | 2000 |
| Molecular mechanisms for protein-encoded inheritance JJW Wiltzius, M Landau, R Nelson, MR Sawaya, MI Apostol, ... Nature structural & molecular biology 16 (9), 973-978, 2009 | 307 | 2009 |
| Site-directed spin labeling of a genetically encoded unnatural amino acid MR Fleissner, EM Brustad, T Kálai, C Altenbach, D Cascio, FB Peters, ... Proceedings of the National Academy of Sciences 106 (51), 21637-21642, 2009 | 300 | 2009 |
