A mitochondrial enzyme degrades carotenoids and protects against oxidative stress J Amengual, GP Lobo, M Golczak, HNM Li, T Klimova, CL Hoppel, A Wyss, ... The FASEB Journal 25 (3), 948, 2011 | 353 | 2011 |
ISX is a retinoic acid-sensitive gatekeeper that controls intestinal β, β-carotene absorption and vitamin A production GP Lobo, S Hessel, A Eichinger, N Noy, AR Moise, A Wyss, K Palczewski, ... The FASEB Journal 24 (6), 1656, 2010 | 271 | 2010 |
Germline mutations and variants in the succinate dehydrogenase genes in Cowden and Cowden-like syndromes Y Ni, KM Zbuk, T Sadler, A Patocs, G Lobo, E Edelman, P Platzer, ... The American Journal of Human Genetics 83 (2), 261-268, 2008 | 253 | 2008 |
PTEN mutations are common in sporadic microsatellite stable colorectal cancer NT Nassif, GP Lobo, X Wu, CJA Henderson, CD Morrison, C Eng, ... Oncogene 23 (2), 617-628, 2004 | 197 | 2004 |
β, β-carotene decreases peroxisome proliferator receptor γ activity and reduces lipid storage capacity of adipocytes in a β, β-carotene oxygenase 1-dependent manner GP Lobo, J Amengual, HNM Li, M Golczak, ML Bonet, K Palczewski, ... Journal of biological chemistry 285 (36), 27891-27899, 2010 | 161 | 2010 |
Mammalian carotenoid-oxygenases: key players for carotenoid function and homeostasis GP Lobo, J Amengual, G Palczewski, D Babino, J Von Lintig Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2012 | 146 | 2012 |
BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway GP Lobo, A Isken, S Hoff, D Babino, J von Lintig Development 139 (16), 2966-2977, 2012 | 139 | 2012 |
Emerging nano-formulations and nanomedicines applications for ocular drug delivery D Khiev, ZA Mohamed, R Vichare, R Paulson, S Bhatia, S Mohapatra, ... Nanomaterials 11 (1), 173, 2021 | 134 | 2021 |
Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX GP Lobo, J Amengual, D Baus, RA Shivdasani, D Taylor, J Von Lintig Journal of Biological Chemistry 288 (13), 9017-9027, 2013 | 131 | 2013 |
Genetic ablation of the fatty acid–binding protein FABP5 suppresses HER2-induced mammary tumorigenesis L Levi, G Lobo, MK Doud, J Von Lintig, D Seachrist, GP Tochtrop, N Noy Cancer research 73 (15), 4770-4780, 2013 | 128 | 2013 |
A genetic dissection of intestinal fat-soluble vitamin and carotenoid absorption MAK Widjaja-Adhi, GP Lobo, M Golczak, J Von Lintig Human molecular genetics 24 (11), 3206-3219, 2015 | 121 | 2015 |
Increased adiposity in the retinol saturase-knockout mouse AR Moise, GP Lobo, B Erokwu, DL Wilson, D Peck, S Alvarez, ... The FASEB Journal 24 (4), 1261, 2010 | 65 | 2010 |
Activation of retinoic acid receptors by dihydroretinoids AR Moise, S Alvarez, M Domínguez, R Alvarez, M Golczak, GP Lobo, ... Molecular pharmacology 76 (6), 1228-1237, 2009 | 62 | 2009 |
Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function GP Lobo, KA Waite, SM Planchon, T Romigh, NT Nassif, C Eng Human molecular genetics 18 (15), 2851-2862, 2009 | 58 | 2009 |
Defects in the exocyst-cilia machinery cause bicuspid aortic valve disease and aortic stenosis D Fulmer, K Toomer, L Guo, K Moore, J Glover, R Moore, R Stairley, ... Circulation 140 (16), 1331-1341, 2019 | 53 | 2019 |
ATP modulates PTEN subcellular localization in multiple cancer cell lines GP Lobo, KA Waite, SM Planchon, T Romigh, JA Houghton, C Eng Human molecular genetics 17 (18), 2877-2885, 2008 | 51 | 2008 |
The exocyst is required for photoreceptor ciliogenesis and retinal development GP Lobo, D Fulmer, L Guo, X Zuo, Y Dang, SH Kim, Y Su, K George, ... Journal of Biological Chemistry 292 (36), 14814-14826, 2017 | 50 | 2017 |
Alterations of the Birt-Hogg-Dube gene (BHD) in sporadic colorectal tumours K Kahnoski, SK Khoo, NT Nassif, J Chen, GP Lobo, E Segelov, BT Teh Journal of medical genetics 40 (7), 511-515, 2003 | 40 | 2003 |
Mutation of wrb, a component of the guided entry of tail-anchored protein pathway, disrupts photoreceptor synapse structure and function LL Daniele, F Emran, GP Lobo, RJ Gaivin, BD Perkins Investigative Ophthalmology & Visual Science 57 (7), 2942-2954, 2016 | 35 | 2016 |
Vitamin A transporters in visual function: a mini review on membrane receptors for dietary vitamin A uptake, storage, and transport to the eye N Martin Ask, M Leung, R Radhakrishnan, GP Lobo Nutrients 13 (11), 3987, 2021 | 34 | 2021 |