| A common haplotype lowers PU. 1 expression in myeloid cells and delays onset of Alzheimer's disease K Huang, E Marcora, AA Pimenova, AF Di Narzo, M Kapoor, SC Jin, ... Nature neuroscience 20 (8), 1052-1061, 2017 | 380 | 2017 |
| An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations U Dube, JL Del-Aguila, Z Li, JP Budde, S Jiang, S Hsu, L Ibanez, ... Nature neuroscience 22 (11), 1903-1912, 2019 | 299 | 2019 |
| The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk Y Deming, F Filipello, F Cignarella, C Cantoni, S Hsu, R Mikesell, Z Li, ... Science translational medicine 11 (505), eaau2291, 2019 | 254 | 2019 |
| Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers Y Deming, Z Li, M Kapoor, O Harari, JL Del-Aguila, K Black, D Carrell, ... Acta neuropathologica 133 (5), 839-856, 2017 | 226 | 2017 |
| Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders C Yang, FHG Farias, L Ibanez, A Suhy, B Sadler, MV Fernandez, F Wang, ... Nature neuroscience 24 (9), 1302-1312, 2021 | 186 | 2021 |
| A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain JL Del-Aguila, Z Li, U Dube, KA Mihindukulasuriya, JP Budde, ... Alzheimer's research & therapy 11, 1-16, 2019 | 175 | 2019 |
| Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms C Cruchaga, JL Del-Aguila, B Saef, K Black, MV Fernandez, J Budde, ... Alzheimer's & Dementia 14 (2), 205-214, 2018 | 141 | 2018 |
| Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease H Holstege, M Hulsman, C Charbonnier, B Grenier-Boley, O Quenez, ... Nature genetics 54 (12), 1786-1794, 2022 | 132 | 2022 |
| Mitochondria function associated genes contribute to Parkinson’s Disease risk and later age at onset KJ Billingsley, IA Barbosa, S Bandrés-Ciga, JP Quinn, VJ Bubb, ... npj Parkinson's Disease 5 (1), 8, 2019 | 116 | 2019 |
| Genome-wide significant risk factors for Alzheimer’s disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment Molecular psychiatry, 2016 | 116* | 2016 |
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| Sex-specific genetic predictors of Alzheimer’s disease biomarkers Y Deming, L Dumitrescu, LL Barnes, M Thambisetty, B Kunkle, KA Gifford, ... Acta neuropathologica 136, 857-872, 2018 | 100 | 2018 |
| TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers JL Del-Aguila, BA Benitez, Z Li, U Dube, KA Mihindukulasuriya, JP Budde, ... Molecular neurodegeneration 14, 1-13, 2019 | 88 | 2019 |
| Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer’s disease resilience PG Ridge, CM Karch, S Hsu, I Arano, CC Teerlink, MTW Ebbert, ... Genome medicine 9, 1-14, 2017 | 83 | 2017 |
| HemoTypeSC, a low-cost point-of-care testing device for sickle cell disease: Promises and challenges O Nnodu, H Isa, M Nwegbu, C Ohiaeri, S Adegoke, R Chianumba, ... Blood Cells, Molecules, and Diseases 78, 22-28, 2019 | 71 | 2019 |
| Assessment of the genetic architecture of Alzheimer’s disease risk in rate of memory decline JL Del-Aguila, MV Fernández, S Schindler, L Ibanez, Y Deming, S Ma, ... Journal of Alzheimer’s Disease 62 (2), 745-756, 2018 | 67 | 2018 |
| PLD3 in non-familial Alzheimer's disease S Heilmann, D Drichel, J Clarimon, V Fernández, A Lacour, H Wagner, ... Nature 520 (7545), E3-E5, 2015 | 67 | 2015 |
| The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion Z Li, FHG Farias, U Dube, JL Del-Aguila, KA Mihindukulasuriya, ... Acta neuropathologica 139 (1), 45-61, 2020 | 66 | 2020 |
| Genetic structure in the blue and red shrimp Aristeus antennatus and the role played by hydrographical and oceanographical barriers MV Fernández, S Heras, F Maltagliati, A Turco, MI Roldán Marine Ecology Progress Series 421, 163-171, 2011 | 65 | 2011 |
| Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP S Jiang, N Wen, Z Li, U Dube, J Del Aguila, J Budde, R Martinez, S Hsu, ... Translational psychiatry 8 (1), 265, 2018 | 62 | 2018 |
Carlos CruchagaProfessor. NeuroGenomics and Informatics Center DirectorVerified email at wustl.edu
