| Patient-derived xenograft models: an emerging platform for translational cancer research M Hidalgo, F Amant, AV Biankin, E Budinská, AT Byrne, C Caldas, ... Cancer discovery 4 (9), 998-1013, 2014 | 1777 | 2014 |
| Dissociation between steroid receptor expression and cell proliferation in the human breast RB Clarke, A Howell, CS Potten, E Anderson Cancer research 57 (22), 4987-4991, 1997 | 853 | 1997 |
| Aberrant activation of notch signaling in human breast cancer S Stylianou, RB Clarke, K Brennan Cancer research 66 (3), 1517-1525, 2006 | 727 | 2006 |
| Interrogating open issues in cancer precision medicine with patient-derived xenografts AT Byrne, DG Alférez, F Amant, D Annibali, J Arribas, AV Biankin, A Bruna, ... Nature Reviews Cancer 17 (4), 254-268, 2017 | 719 | 2017 |
| Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor H Harrison, G Farnie, SJ Howell, RE Rock, S Stylianou, KR Brennan, ... Cancer research 70 (2), 709-718, 2010 | 675 | 2010 |
| Identification of a putative intestinal stem cell and early lineage marker; musashi-1 CS Potten, C Booth, GL Tudor, D Booth, G Brady, P Hurley, G Ashton, ... Differentiation 71 (1), 28-41, 2003 | 600 | 2003 |
| Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ... Breast Cancer Research 15, 1-37, 2013 | 537 | 2013 |
| Risk determination and prevention of breast cancer A Howell, AS Anderson, RB Clarke, SW Duffy, DG Evans, ... Breast Cancer Research 16, 1-19, 2014 | 535 | 2014 |
| Mammary stem cells and breast cancer—role of Notch signalling G Farnie, RB Clarke Stem cell reviews 3, 169-175, 2007 | 481 | 2007 |
| A detailed mammosphere assay protocol for the quantification of breast stem cell activity FL Shaw, H Harrison, K Spence, MP Ablett, BM Simões, G Farnie, ... Journal of mammary gland biology and neoplasia 17, 111-117, 2012 | 455 | 2012 |
| Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways G Farnie, RB Clarke, K Spence, N Pinnock, K Brennan, NG Anderson, ... Journal of the National Cancer Institute 99 (8), 616-627, 2007 | 431 | 2007 |
| A putative human breast stem cell population is enriched for steroid receptor-positive cells RB Clarke, K Spence, E Anderson, A Howell, H Okano, CS Potten Developmental biology 277 (2), 443-456, 2005 | 412 | 2005 |
| Estrogen receptor-positive proliferating cells in the normal and precancerous breast BS Shoker, C Jarvis, RB Clarke, E Anderson, J Hewlett, MPA Davies, ... The American journal of pathology 155 (6), 1811-1815, 1999 | 360 | 1999 |
| Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells JK Singh, BM Simões, SJ Howell, G Farnie, RB Clarke Breast Cancer Research 15, 1-9, 2013 | 296 | 2013 |
| Origins of breast cancer subtypes and therapeutic implications AH Sims, A Howell, SJ Howell, RB Clarke Nature Clinical Practice Oncology 4 (9), 516-525, 2007 | 288 | 2007 |
| Patient-derived xenograft (PDX) models in basic and translational breast cancer research LE Dobrolecki, SD Airhart, DG Alferez, S Aparicio, F Behbod, ... Cancer and Metastasis Reviews 35, 547-573, 2016 | 287 | 2016 |
| Estrogen responsiveness and control of normal human breast proliferation E Anderson, RB Clarke, A Howell Journal of mammary gland biology and neoplasia 3, 23-35, 1998 | 256 | 1998 |
| The proliferation of normal human breast tissue implanted into athymic nude mice is stimulated by estrogen but not progesterone IJ Laidlaw, RB Clarke, A Howell, AW Owen, CS Potten, E Anderson Endocrinology 136 (1), 164-171, 1995 | 254 | 1995 |
| Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and-independent mechanisms JK Singh, G Farnie, NJ Bundred, BM Simões, A Shergill, G Landberg, ... Clinical cancer research 19 (3), 643-656, 2013 | 247 | 2013 |
| The centrosomal kinase Nek2 displays elevated levels of protein expression in human breast cancer DG Hayward, RB Clarke, AJ Faragher, MR Pillai, IM Hagan, AM Fry Cancer research 64 (20), 7370-7376, 2004 | 234 | 2004 |
Anthony Howell, Howell A, Howell TProfessor of Medical Oncology, Manchester UniversityVerified email at picr.man.ac.uk
