| Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells F Zhan, J Hardin, B Kordsmeier, K Bumm, M Zheng, E Tian, R Sanderson, ... Blood, The Journal of the American Society of Hematology 99 (5), 1745-1757, 2002 | 825 | 2002 |
| Proteoglycans in cancer biology, tumour microenvironment and angiogenesis RV Iozzo, RD Sanderson Journal of cellular and molecular medicine 15 (5), 1013-1031, 2011 | 651 | 2011 |
| B lymphocytes express and lose syndecan at specific stages of differentiation. RD Sanderson, P Lalor, M Bernfield Cell regulation 1 (1), 27-35, 1989 | 453 | 1989 |
| Heparanase regulates secretion, composition, and function of Tumor Cell-derived Exosomes*♦ CA Thompson, A Purushothaman, VC Ramani, I Vlodavsky, ... Journal of Biological Chemistry 288 (14), 10093-10099, 2013 | 364 | 2013 |
| The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to β1 integrin–dependent cell spreading K Iba, R Albrechtsen, B Gilpin, C Fröhlich, F Loechel, A Zolkiewska, ... The Journal of cell biology 149 (5), 1143-1156, 2000 | 338 | 2000 |
| Fibronectin on the surface of myeloma cell-derived exosomes mediates exosome-cell interactions A Purushothaman, SK Bandari, J Liu, JA Mobley, EE Brown, ... Journal of Biological Chemistry 291 (4), 1652-1663, 2016 | 335 | 2016 |
| Osteoprotegerin is bound, internalized, and degraded by multiple myeloma cells T Standal, C Seidel, Ø Hjertner, T Plesner, RD Sanderson, A Waage, ... Blood, The Journal of the American Society of Hematology 100 (8), 3002-3007, 2002 | 335 | 2002 |
| Proteoglycan chemical diversity drives multifunctional cell regulation and therapeutics NK Karamanos, Z Piperigkou, AD Theocharis, H Watanabe, M Franchi, ... Chemical reviews 118 (18), 9152-9232, 2018 | 334 | 2018 |
| Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis Y Yang, V MacLeod, HQ Miao, A Theus, F Zhan, JD Shaughnessy, ... Journal of Biological Chemistry 282 (18), 13326-13333, 2007 | 329 | 2007 |
| Syndecan, a developmentally regulated cell surface proteoglycan that binds extracellular matrix and growth factors M Bernfield, RD Sanderson Philosophical Transactions of the Royal Society of London. B, Biological …, 1990 | 311 | 1990 |
| Heparan sulfate proteoglycans in invasion and metastasis RD Sanderson Seminars in cell & developmental biology 12 (2), 89-98, 2001 | 301 | 2001 |
| SST0001, a chemically modified heparin, inhibits myeloma growth and angiogenesis via disruption of the heparanase/syndecan-1 axis JP Ritchie, VC Ramani, Y Ren, A Naggi, G Torri, B Casu, S Penco, ... Clinical Cancer Research 17 (6), 1382-1393, 2011 | 292 | 2011 |
| Expression of syndecan regulates human myeloma plasma cell adhesion to type I collagen RC Ridley, H Xiao, H Hata, J Woodliff, J Epstein, RD Sanderson | 284 | 1993 |
| Syndecan-1 is a multifunctional regulator of myeloma pathobiology: control of tumor cell survival, growth, and bone cell differentiation MV Dhodapkar, E Abe, A Theus, M Lacy, JK Langford, B Barlogie, ... Blood, The Journal of the American Society of Hematology 91 (8), 2679-2688, 1998 | 282 | 1998 |
| Heparanase: busy at the cell surface L Fux, N Ilan, RD Sanderson, I Vlodavsky Trends in biochemical sciences 34 (10), 511-519, 2009 | 280 | 2009 |
| Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis A Purushothaman, T Uyama, F Kobayashi, S Yamada, K Sugahara, ... Blood, The Journal of the American Society of Hematology 115 (12), 2449-2457, 2010 | 274 | 2010 |
| Heparan sulfate proteoglycans and heparanase—partners in osteolytic tumor growth and metastasis RD Sanderson, Y Yang, LJ Suva, T Kelly Matrix Biology 23 (6), 341-352, 2004 | 255 | 2004 |
| Soluble syndecan-1 promotes growth of myeloma tumors in vivo Y Yang, S Yaccoby, W Liu, JK Langford, CY Pumphrey, A Theus, ... Blood, The Journal of the American Society of Hematology 100 (2), 610-617, 2002 | 254 | 2002 |
| The epidermal growth factor–like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans M Stacey, GW Chang, JQ Davies, MJ Kwakkenbos, RD Sanderson, ... Blood 102 (8), 2916-2924, 2003 | 248 | 2003 |
| Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior SK Bandari, A Purushothaman, VC Ramani, GJ Brinkley, ... Matrix biology 65, 104-118, 2018 | 236 | 2018 |
Renato V. Iozzo, MD PhD (Honoris ca...Thomas Jefferson University, Philadelphia, PA, USA 😎 Editor-in-Chief Proteoglycan ResearchVerified email at jefferson.edu