FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis S Kir, SA Beddow, VT Samuel, P Miller, SF Previs, K Suino-Powell, HE Xu, ... Science 331 (6024), 1621-1624, 2011 | 686 | 2011 |
Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia S Kir, JP White, S Kleiner, L Kazak, P Cohen, VE Baracos, ... Nature 513 (7516), 100-104, 2014 | 673 | 2014 |
siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy EYW Chan, S Kir, SA Tooze Journal of Biological Chemistry 282 (35), 25464-25474, 2007 | 565 | 2007 |
Parathyroid hormone directs bone marrow mesenchymal cell fate Y Fan, J Hanai, PT Le, R Bi, D Maridas, V DeMambro, CA Figueroa, S Kir, ... Cell metabolism 25 (3), 661-672, 2017 | 396 | 2017 |
PTH/PTHrP receptor mediates cachexia in models of kidney failure and cancer S Kir, H Komaba, AP Garcia, KP Economopoulos, W Liu, B Lanske, ... Cell metabolism 23 (2), 315-323, 2016 | 293 | 2016 |
The G protein-coupled bile acid receptor, TGR5, stimulates gallbladder filling T Li, SR Holmstrom, S Kir, M Umetani, DR Schmidt, SA Kliewer, ... Molecular endocrinology 25 (6), 1066-1071, 2011 | 281 | 2011 |
Nuclear receptors HNF4α and LRH-1 cooperate in regulating Cyp7a1 in vivo S Kir, Y Zhang, RD Gerard, SA Kliewer, DJ Mangelsdorf Journal of Biological Chemistry 287 (49), 41334-41341, 2012 | 160 | 2012 |
A secreted Slit2 fragment regulates adipose tissue thermogenesis and metabolic function KJ Svensson, JZ Long, MP Jedrychowski, P Cohen, JC Lo, S Serag, S Kir, ... Cell metabolism 23 (3), 454-466, 2016 | 157 | 2016 |
Roles of FGF19 in liver metabolism S Kir, SA Kliewer, DJ Mangelsdorf Cold Spring Harbor symposia on quantitative biology 76, 139-144, 2011 | 138 | 2011 |
Conversion of a paracrine fibroblast growth factor into an endocrine fibroblast growth factor R Goetz, M Ohnishi, S Kir, H Kurosu, L Wang, J Pastor, J Ma, W Gai, ... Journal of Biological Chemistry 287 (34), 29134-29146, 2012 | 116 | 2012 |
Cachexia and brown fat: a burning issue in cancer S Kir, BM Spiegelman Trends in cancer 2 (9), 461-463, 2016 | 94 | 2016 |
Tumor-derived ligands trigger tumor growth and host wasting via differential MEK activation W Song, S Kir, S Hong, Y Hu, X Wang, R Binari, HW Tang, V Chung, ... Developmental Cell 48 (2), 277-286. e6, 2019 | 71 | 2019 |
EDA2R–NIK signalling promotes muscle atrophy linked to cancer cachexia SN Bilgic, A Domaniku, B Toledo, S Agca, BZC Weber, DH Arabaci, ... Nature 617 (7962), 827-834, 2023 | 53 | 2023 |
Metabolic reprogramming in adipose tissue during cancer cachexia BZC Weber, DH Arabaci, S Kir Frontiers in oncology 12, 848394, 2022 | 30 | 2022 |
A resampling-based meta-analysis for detection of differential gene expression in breast cancer B Gur-Dedeoglu, O Konu, S Kir, AR Ozturk, B Bozkurt, G Ergul, IG Yulug BMC cancer 8, 1-16, 2008 | 29 | 2008 |
Inhibition of epidermal growth factor receptor suppresses parathyroid hormone‐related protein expression in tumours and ameliorates cancer‐associated cachexia BZC Weber, S Agca, A Domaniku, SN Bilgic, DH Arabaci, S Kir Journal of cachexia, sarcopenia and muscle 13 (3), 1582-1594, 2022 | 16 | 2022 |
Muscle wasting: emerging pathways and potential drug targets A Domaniku, SN Bilgic, S Kir Trends in Pharmacological Sciences, 2023 | 12 | 2023 |
Oncostatin M signaling drives cancer-associated skeletal muscle wasting A Domaniku-Waraich, S Agca, B Toledo, M Sucuoglu, SD Özen, SN Bilgic, ... Cell Reports Medicine 5 (4), 2024 | 7* | 2024 |
Parathyroid hormone related protein (PTHrP) in patients with pancreatic carcinoma and overt signs of disease progression and host tissue wasting BM Iresjö, S Kir, K Lundholm Translational Oncology 36, 101752, 2023 | 4 | 2023 |
Ectodysplasin A2 receptor signaling in skeletal muscle pathophysiology SD Özen, S Kir Trends in Molecular Medicine, 2024 | 3 | 2024 |