Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors A Gazit, P Yaish, C Gilon, A Levitzki Journal of medicinal chemistry 32 (10), 2344-2352, 1989 | 771 | 1989 |
Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors P Yaish, A Gazit, C Gilon, A Levitzki Science 242 (4880), 933-935, 1988 | 767 | 1988 |
N-methylation of peptides: a new perspective in medicinal chemistry J Chatterjee, C Gilon, A Hoffman, H Kessler Accounts of chemical research 41 (10), 1331-1342, 2008 | 682 | 2008 |
Attachment of drugs to polyethylene glycols S Zalipsky, C Gilon, A Zilkha European Polymer Journal 19 (12), 1177-1183, 1983 | 564 | 1983 |
Improving oral bioavailability of peptides by multiple N‐methylation: somatostatin analogues E Biron, J Chatterjee, O Ovadia, D Langenegger, J Brueggen, D Hoyer, ... Angewandte Chemie International Edition 47 (14), 2595-2599, 2008 | 430 | 2008 |
The effect of tyrosine‐specific protein phosphorylation on the assembly of adherens‐type junctions. T Volberg, Y Zick, R Dror, I Sabanay, C Gilon, A Levitzki, B Geiger The EMBO journal 11 (5), 1733-1742, 1992 | 368 | 1992 |
Highly selective agonists for substance P receptor subtypes. U Wormser, R Laufer, Y Hart, M Chorev, C Gilon, Z Selinger The EMBO journal 5 (11), 2805-2808, 1986 | 349 | 1986 |
Tyrphostins inhibit epidermal growth factor (EGF)-receptor tyrosine kinase activity in living cells and EGF-stimulated cell proliferation RM Lyall, A Zilberstein, A Gazit, C Gilon, A Levitzki, J Schlessinger Journal of Biological Chemistry 264 (24), 14503-14509, 1989 | 334 | 1989 |
Tyrphostins. II. Heterocyclic and. alpha.-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases A Gazit, N Osherov, I Posner, P Yaish, E Poradosu, C Gilon, A Levitzki Journal of medicinal chemistry 34 (6), 1896-1907, 1991 | 323 | 1991 |
Backbone cyclization: a new method for conferring conformational constraint on peptides C Gilon, D Halle, M Chorev, Z Selincer, G Byk Biopolymers: Original Research on Biomolecules 31 (6), 745-750, 1991 | 289 | 1991 |
Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin. R Laufer, U Wormser, ZY Friedman, C Gilon, M Chorev, Z Selinger Proceedings of the National Academy of Sciences 82 (21), 7444-7448, 1985 | 247 | 1985 |
Styryl compounds which inhibit EGF receptor protein tyrosine kinase A Levitzki, C Gilon, M Chorev, A Gazit US Patent 5,217,999, 1993 | 242 | 1993 |
Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins N Osherov, A Gazit, C Gilon, A Levitzki Journal of Biological Chemistry 268 (15), 11134-11142, 1993 | 235 | 1993 |
Intestinal permeability of cyclic peptides: common key backbone motifs identified JG Beck, J Chatterjee, B Laufer, MU Kiran, AO Frank, S Neubauer, ... Journal of the American Chemical Society 134 (29), 12125-12133, 2012 | 224 | 2012 |
Styryl-substituted pyridyl compounds which inhibit EGF receptor tyrosine kinase AP Spada, PE Persons, A Levitzki, C Gilon US Patent 5,302,606, 1994 | 222 | 1994 |
The effect of multiple N-methylation on intestinal permeability of cyclic hexapeptides O Ovadia, S Greenberg, J Chatterjee, B Laufer, F Opperer, H Kessler, ... Molecular pharmaceutics 8 (2), 479-487, 2011 | 176 | 2011 |
Tyrphostins as molecular tools and potential antiproliferative drugs A Levitzki, C Gilon Trends in pharmacological sciences 12, 171-174, 1991 | 165 | 1991 |
Orally active peptides: is there a magic bullet? AFB Räder, M Weinmüller, F Reichart, A Schumacher‐Klinger, ... Angewandte Chemie International Edition 57 (44), 14414-14438, 2018 | 160 | 2018 |
Direct translocation of histone molecules across cell membranes E Hariton-Gazal, J Rosenbluh, A Graessmann, C Gilon, A Loyter Journal of Cell Science 116 (22), 4577-4586, 2003 | 153 | 2003 |
Characterization of a neurokinin B receptor site in rat brain using a highly selective radioligand. R Laufer, C Gilon, M Chorev, Z Selinger Journal of Biological Chemistry 261 (22), 10257-10263, 1986 | 153 | 1986 |