Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells DA Lawson, NR Bhakta, K Kessenbrock, KD Prummel, Y Yu, K Takai, ... Nature 526 (7571), 131-135, 2015 | 991 | 2015 |
Tumour heterogeneity and metastasis at single-cell resolution DA Lawson, K Kessenbrock, RT Davis, N Pervolarakis, Z Werb Nature cell biology 20 (12), 1349-1360, 2018 | 572 | 2018 |
The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis LI Xin, DA Lawson, ON Witte Proceedings of the National Academy of Sciences 102 (19), 6942-6947, 2005 | 538 | 2005 |
Isolation and functional characterization of murine prostate stem cells DA Lawson, LI Xin, RU Lukacs, D Cheng, ON Witte Proceedings of the National Academy of Sciences 104 (1), 181-186, 2007 | 480 | 2007 |
Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics AS Goldstein, DA Lawson, D Cheng, W Sun, IP Garraway, ON Witte Proceedings of the National Academy of Sciences 105 (52), 20882-20887, 2008 | 405 | 2008 |
Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation S Wang, AJ Garcia, M Wu, DA Lawson, ON Witte, H Wu Proceedings of the National Academy of Sciences 103 (5), 1480-1485, 2006 | 391 | 2006 |
Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity QH Nguyen, N Pervolarakis, K Blake, D Ma, RT Davis, N James, ... Nature communications 9 (1), 2028, 2018 | 372 | 2018 |
Basal epithelial stem cells are efficient targets for prostate cancer initiation DA Lawson, Y Zong, S Memarzadeh, L Xin, J Huang, ON Witte Proceedings of the National Academy of Sciences 107 (6), 2610-2615, 2010 | 342 | 2010 |
Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing RT Davis, K Blake, D Ma, MBI Gabra, GA Hernandez, AT Phung, Y Yang, ... Nature cell biology 22 (3), 310-320, 2020 | 257 | 2020 |
ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells Y Zong, L Xin, AS Goldstein, DA Lawson, MA Teitell, ON Witte Proceedings of the National Academy of Sciences 106 (30), 12465-12470, 2009 | 257 | 2009 |
Lgr5-expressing cells are sufficient and necessary for postnatal mammary gland organogenesis V Plaks, A Brenot, DA Lawson, JR Linnemann, EC Van Kappel, KC Wong, ... Cell reports 3 (1), 70-78, 2013 | 252 | 2013 |
Stem cells in prostate cancer initiation and progression DA Lawson, ON Witte The Journal of clinical investigation 117 (8), 2044-2050, 2007 | 227 | 2007 |
Self-renewal and multilineage differentiation in vitro from murine prostate stem cells L Xin, RU Lukacs, DA Lawson, D Cheng, ON Witte Stem cells 25 (11), 2760-2769, 2007 | 226 | 2007 |
Lin−Sca-1+CD49fhigh Stem/Progenitors Are Tumor-Initiating Cells in the Pten-Null Prostate Cancer Model DJ Mulholland, L Xin, A Morim, D Lawson, O Witte, H Wu Cancer research 69 (22), 8555-8562, 2009 | 223 | 2009 |
Isolation, cultivation and characterization of adult murine prostate stem cells RU Lukacs, AS Goldstein, DA Lawson, D Cheng, ON Witte Nature protocols 5 (4), 702-713, 2010 | 211 | 2010 |
Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor L Xin, MA Teitell, DA Lawson, A Kwon, IK Mellinghoff, ON Witte Proceedings of the National Academy of Sciences 103 (20), 7789-7794, 2006 | 199 | 2006 |
PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression D Horiuchi, R Camarda, AY Zhou, C Yau, O Momcilovic, S Balakrishnan, ... Nature medicine 22 (11), 1321-1329, 2016 | 169 | 2016 |
A role for matrix metalloproteinases in regulating mammary stem cell function via the Wnt signaling pathway K Kessenbrock, GJP Dijkgraaf, DA Lawson, LE Littlepage, P Shahi, ... Cell stem cell 13 (3), 300-313, 2013 | 166 | 2013 |
Identification of CD166 as a surface marker for enriching prostate stem/progenitor and cancer initiating cells J Jiao, A Hindoyan, S Wang, LM Tran, AS Goldstein, D Lawson, D Chen, ... Public Library of Science 7 (8), e42564, 2012 | 143 | 2012 |
Mechanoresponsive stem cells to target cancer metastases through biophysical cues L Liu, SX Zhang, W Liao, HP Farhoodi, CW Wong, CC Chen, AI Ségaliny, ... Science translational medicine 9 (400), eaan2966, 2017 | 113 | 2017 |