| Sensitivity of secondary structure propensities to sequence differences between α‐and γ‐synuclein: implications for fibrillation JA Marsh, VK Singh, Z Jia, JD Forman‐Kay Protein Science 15 (12), 2795-2804, 2006 | 824 | 2006 |
| Structure, dynamics, assembly, and evolution of protein complexes JA Marsh, SA Teichmann Annual review of biochemistry 84 (1), 551-575, 2015 | 471 | 2015 |
| Sequence determinants of compaction in intrinsically disordered proteins JA Marsh, JD Forman-Kay Biophysical journal 98 (10), 2383-2390, 2010 | 423 | 2010 |
| Kinetic analysis of protein stability reveals age-dependent degradation E McShane, C Sin, H Zauber, JN Wells, N Donnelly, X Wang, J Hou, ... Cell 167 (3), 803-815. e21, 2016 | 308 | 2016 |
| Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase T Mittag, J Marsh, A Grishaev, S Orlicky, H Lin, F Sicheri, M Tyers, ... Structure 18 (4), 494-506, 2010 | 307 | 2010 |
| Protein complexes are under evolutionary selection to assemble via ordered pathways JA Marsh, H Hernandez, Z Hall, SE Ahnert, T Perica, CV Robinson, ... Cell 153 (2), 461-470, 2013 | 258 | 2013 |
| Principles of assembly reveal a periodic table of protein complexes SE Ahnert, JA Marsh, H Hernández, CV Robinson, SA Teichmann Science 350 (6266), aaa2245, 2015 | 242 | 2015 |
| Relative solvent accessible surface area predicts protein conformational changes upon binding JA Marsh, SA Teichmann Structure 19 (6), 859-867, 2011 | 239 | 2011 |
| Structure and disorder in an unfolded state under nondenaturing conditions from ensemble models consistent with a large number of experimental restraints JA Marsh, JD Forman-Kay Journal of molecular biology 391 (2), 359-374, 2009 | 190 | 2009 |
| Loss-of-function, gain-of-function and dominant-negative mutations have profoundly different effects on protein structure L Gerasimavicius, BJ Livesey, JA Marsh Nature communications 13 (1), 3895, 2022 | 182 | 2022 |
| Mutations in COPA lead to abnormal trafficking of STING to the Golgi and interferon signaling A Lepelley, MJ Martin-Niclós, M Le Bihan, JA Marsh, C Uggenti, GI Rice, ... Journal of Experimental Medicine 217 (11), e20200600, 2020 | 178 | 2020 |
| SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome ND Shaw, H Brand, ZA Kupchinsky, H Bengani, L Plummer, TI Jones, ... Nature genetics 49 (2), 238-248, 2017 | 178 | 2017 |
| Characterization of disordered proteins with ENSEMBLE M Krzeminski, JA Marsh, C Neale, WY Choy, JD Forman-Kay Bioinformatics 29 (3), 398-399, 2013 | 167 | 2013 |
| Using deep mutational scanning to benchmark variant effect predictors and identify disease mutations BJ Livesey, JA Marsh Molecular systems biology 16 (7), e9380, 2020 | 158 | 2020 |
| Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions P Heyn, CV Logan, A Fluteau, RC Challis, T Auchynnikava, CA Martin, ... Nature genetics 51 (1), 96-105, 2019 | 158 | 2019 |
| Interrogation of mammalian protein complex structure, function, and membership using genome-scale fitness screens J Pan, RM Meyers, BC Michel, N Mashtalir, AE Sizemore, JN Wells, ... Cell systems 6 (5), 555-568. e7, 2018 | 150 | 2018 |
| Improved structural characterizations of the drkN SH3 domain unfolded state suggest a compact ensemble with native-like and non-native structure JA Marsh, C Neale, FE Jack, WY Choy, AY Lee, KA Crowhurst, ... Journal of molecular biology 367 (5), 1494-1510, 2007 | 143 | 2007 |
| Alpha helices are more robust to mutations than beta strands G Abrusán, JA Marsh PLoS computational biology 12 (12), e1005242, 2016 | 141 | 2016 |
| Ensemble modeling of protein disordered states: experimental restraint contributions and validation JA Marsh, JD Forman‐Kay Proteins: Structure, Function, and Bioinformatics 80 (2), 556-572, 2012 | 138 | 2012 |
| Evolution of condensin and cohesin complexes driven by replacement of Kite by Hawk proteins JN Wells, TG Gligoris, KA Nasmyth, JA Marsh Current Biology 27 (1), R17-R18, 2017 | 137 | 2017 |
Sarah A. TeichmannUniversity of CambridgeVerified email at cam.ac.uk
