| Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing Q Cheng, T Wei, L Farbiak, LT Johnson, SA Dilliard, DJ Siegwart Nature nanotechnology 15 (4), 313-320, 2020 | 1480 | 2020 |
| On the mechanism of tissue-specific mRNA delivery by selective organ targeting nanoparticles SA Dilliard, Q Cheng, DJ Siegwart Proceedings of the national academy of sciences 118 (52), e2109256118, 2021 | 539 | 2021 |
| Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing T Wei, Q Cheng (Co-First), YL Min, EN Olson, DJ Siegwart Nature communications 11 (1), 1-12, 2020 | 524 | 2020 |
| Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR–Cas gene editing S Liu, Q Cheng, T Wei, X Yu, LT Johnson, L Farbiak, DJ Siegwart Nature materials 20 (5), 701-710, 2021 | 434 | 2021 |
| Anticancer drug nanomicelles formed by self-assembling amphiphilic dendrimer to combat cancer drug resistance T Wei, C Chen, J Liu, C Liu, P Posocco, X Liu, Q Cheng, S Huo, Z Liang, ... Proceedings of the National Academy of Sciences 112 (10), 2978-2983, 2015 | 394 | 2015 |
| Preparation of selective organ-targeting (SORT) lipid nanoparticles (LNPs) using multiple technical methods for tissue-specific mRNA delivery X Wang, S Liu, Y Sun, X Yu, SM Lee, Q Cheng, T Wei, J Gong, ... Nature protocols 18 (1), 265-291, 2023 | 231 | 2023 |
| Adaptive amphiphilic dendrimer‐based nanoassemblies as robust and versatile siRNA delivery systems X Liu, J Zhou, T Yu, C Chen, Q Cheng, K Sengupta, Y Huang, H Li, C Liu, ... Angewandte Chemie International Edition 53 (44), 11822-11827, 2014 | 222 | 2014 |
| Dendrimer‐based lipid nanoparticles deliver therapeutic FAH mRNA to normalize liver function and extend survival in a mouse model of hepatorenal tyrosinemia type I Q Cheng, T Wei, Y Jia, L Farbiak, K Zhou, S Zhang, Y Wei, H Zhu, ... Advanced materials 30 (52), 1805308, 2018 | 202 | 2018 |
| Functionalized nanoscale micelles improve drug delivery for cancer therapy in vitro and in vivo T Wei, J Liu, H Ma, Q Cheng, Y Huang, J Zhao, S Huo, X Xue, Z Liang, ... Nano letters 13 (6), 2528-2534, 2013 | 190 | 2013 |
| Lipid nanoparticle (LNP) enables mRNA delivery for cancer therapy Y Zong, Y Lin, T Wei, Q Cheng Advanced Materials 35 (51), 2303261, 2023 | 157 | 2023 |
| Membrane‐destabilizing ionizable lipid empowered imaging‐guided siRNA delivery and cancer treatment S Guo, K Li, B Hu, C Li, M Zhang, A Hussain, X Wang, Q Cheng, F Yang, ... Exploration 1 (1), 35-49, 2021 | 140 | 2021 |
| Zwitterionic phospholipidation of cationic polymers facilitates systemic mRNA delivery to spleen and lymph nodes S Liu, X Wang, X Yu, Q Cheng, LT Johnson, S Chatterjee, D Zhang, ... Journal of the American Chemical Society 143 (50), 21321-21330, 2021 | 125 | 2021 |
| Enhanced endosomal/lysosomal escape by distearoyl phosphoethanolamine-polycarboxybetaine lipid for systemic delivery of siRNA Y Li, Q Cheng (Co-first author), Q Jiang, Y Huang, H Liu, Y Zhao, W Cao, ... Journal of Controlled Release 176, 104-114, 2014 | 115 | 2014 |
| Intracellular cleavable poly (2-dimethylaminoethyl methacrylate) functionalized mesoporous silica nanoparticles for efficient siRNA delivery in vitro and in vivo D Lin, Q Cheng (Co-first author), Q Jiang, Y Huang, Z Yang, S Han, ... Nanoscale 5 (10), 4291-4301, 2013 | 113 | 2013 |
| Systemic mRNA delivery to the lungs by functional polyester-based carriers Y Yan, H Xiong, X Zhang, Q Cheng, DJ Siegwart Biomacromolecules 18 (12), 4307-4315, 2017 | 109 | 2017 |
| Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for In Vivo CRISPR/Cas-Based Genome Editing T Wei, Q Cheng, L Farbiak, DG Anderson, R Langer, DJ Siegwart ACS nano 14 (8), 9243-9262, 2020 | 106 | 2020 |
| A systematic study of unsaturation in lipid nanoparticles leads to improved mRNA transfection in vivo SM Lee, Q Cheng, X Yu, S Liu, LT Johnson, DJ Siegwart Angewandte Chemie 133 (11), 5912-5917, 2021 | 104 | 2021 |
| Mastering dendrimer self‐assembly for efficient siRNA delivery: from conceptual design to in vivo efficient gene silencing C Chen, P Posocco, X Liu, Q Cheng, E Laurini, J Zhou, C Liu, Y Wang, ... Small 12 (27), 3667-3676, 2016 | 101 | 2016 |
| The promising nanocarrier for doxorubicin and siRNA co-delivery by PDMAEMA-based amphiphilic nanomicelles Q Cheng, L Du, L Meng, S Han, T Wei, X Wang, Y Wu, X Song, J Zhou, ... ACS applied materials & interfaces 8 (7), 4347-4356, 2016 | 92 | 2016 |
| Gene transfection efficacy and biocompatibility of polycation/DNA complexes coated with enzyme degradable PEGylated hyaluronic acid W Zhang, Q Cheng (Co-first author), S Guo, D Lin, P Huang, J Liu, T Wei, ... Biomaterials 34 (27), 6495-6503, 2013 | 91 | 2013 |
Tuo WeiInstitute of Zoology, Chinese Academy of SciencesVerified email at ioz.ac.cn
