| Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9 JG Doench, N Fusi, M Sullender, M Hegde, EW Vaimberg, KF Donovan, ... Nature biotechnology 34 (2), 184-191, 2016 | 4374 | 2016 |
| FaST linear mixed models for genome-wide association studies C Lippert, J Listgarten, Y Liu, CM Kadie, RI Davidson, D Heckerman Nature methods 8 (10), 833-835, 2011 | 1353 | 2011 |
| Rethinking drug design in the artificial intelligence era P Schneider, WP Walters, AT Plowright, N Sieroka, J Listgarten, ... Nature reviews drug discovery 19 (5), 353-364, 2020 | 705 | 2020 |
| Statistical and computational methods for comparative proteomic profiling using liquid chromatography-tandem mass spectrometry J Listgarten, A Emili Molecular & Cellular Proteomics 4 (4), 419-434, 2005 | 400 | 2005 |
| Improved linear mixed models for genome-wide association studies J Listgarten, C Lippert, CM Kadie, RI Davidson, E Eskin, D Heckerman Nature methods 9 (6), 525-526, 2012 | 399 | 2012 |
| Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs J Listgarten, M Weinstein, BP Kleinstiver, AA Sousa, JK Joung, J Crawford, ... Nature biomedical engineering 2 (1), 38-47, 2018 | 314 | 2018 |
| Orthologous CRISPR–Cas9 enzymes for combinatorial genetic screens FJ Najm, C Strand, KF Donovan, M Hegde, KR Sanson, EW Vaimberg, ... Nature biotechnology 36 (2), 179-189, 2018 | 308 | 2018 |
| Conditioning by adaptive sampling for robust design D Brookes, H Park, J Listgarten Proceedings of the 36th International Conference on Machine Learning 97, 773-782, 2019 | 261* | 2019 |
| Epigenome-wide association studies without the need for cell-type composition J Zou, C Lippert, D Heckerman, M Aryee, J Listgarten Nature methods 11 (3), 309-311, 2014 | 260 | 2014 |
| Predictive models for breast cancer susceptibility from multiple single nucleotide polymorphisms J Listgarten, S Damaraju, B Poulin, L Cook, J Dufour, A Driga, J Mackey, ... Clinical cancer research 10 (8), 2725-2737, 2004 | 250 | 2004 |
| Learning protein fitness models from evolutionary and assay-labeled data C Hsu, H Nisonoff, C Fannjiang, J Listgarten Nature biotechnology 40 (7), 1114-1122, 2022 | 207* | 2022 |
| Additive contribution of HLA class I alleles in the immune control of HIV-1 infection A Leslie, PC Matthews, J Listgarten, JM Carlson, C Kadie, T Ndung'u, ... Journal of virology 84 (19), 9879-9888, 2010 | 197 | 2010 |
| Correction for hidden confounders in the genetic analysis of gene expression J Listgarten, C Kadie, EE Schadt, D Heckerman Proceedings of the National Academy of Sciences 107 (38), 16465-16470, 2010 | 193 | 2010 |
| Lymphovascular invasion is associated with poor survival in gastric cancer: an application of gene-expression and tissue array techniques BJ Dicken, K Graham, SM Hamilton, S Andrews, R Lai, J Listgarten, ... Annals of surgery 243 (1), 64-73, 2006 | 188 | 2006 |
| Multiple alignment of continuous time series J Listgarten, R Neal, S Roweis, A Emili Advances in neural information processing systems 17, 2004 | 177 | 2004 |
| Gaussian process prior variational autoencoders FP Casale, AV Dalca, L Saglietti, J Listgarten, N Fusi Advances in Neural Information Processing Systems 31 (NeurIPS 2018), 2018 | 156 | 2018 |
| Extensive HLA class I allele promiscuity among viral CTL epitopes N Frahm, K Yusim, TJ Suscovich, S Adams, J Sidney, P Hraber, HS Hewitt, ... European journal of immunology 37 (9), 2419-2433, 2007 | 150 | 2007 |
| A genome-to-genome analysis of associations between human genetic variation, HIV-1 sequence diversity, and viral control I Bartha, JM Carlson, CJ Brumme, PJ McLaren, ZL Brumme, M John, ... elife 2, e01123, 2013 | 148 | 2013 |
| Widespread impact of HLA restriction on immune control and escape pathways of HIV-1 JM Carlson, J Listgarten, N Pfeifer, V Tan, C Kadie, BD Walker, T Ndung'u, ... Journal of virology 86 (9), 5230-5243, 2012 | 146 | 2012 |
| Correlates of protective cellular immunity revealed by analysis of population-level immune escape pathways in HIV-1 JM Carlson, CJ Brumme, E Martin, J Listgarten, MA Brockman, AQ Le, ... Journal of virology 86 (24), 13202-13216, 2012 | 127 | 2012 |
Christoph LippertProfessor, Hasso Plattner Institute, Universität PotsdamVerified email at hpi.de