| The cohesin release factor WAPL restricts chromatin loop extension JHI Haarhuis, RH van der Weide, VA Blomen, JO Yáñez-Cuna, ... Cell 169 (4), 693-707. e14, 2017 | 726 | 2017 |
| CTCF binding polarity determines chromatin looping E de Wit, ESM Vos, SJB Holwerda, C Valdes-Quezada, MJAM Verstegen, ... Molecular cell 60 (4), 676-684, 2015 | 719 | 2015 |
| Regulation of disease-associated gene expression in the 3D genome PHL Krijger, W De Laat Nature reviews Molecular cell biology 17 (12), 771-782, 2016 | 359 | 2016 |
| The pluripotent genome in three dimensions is shaped around pluripotency factors E De Wit, BAM Bouwman, Y Zhu, P Klous, E Splinter, MJAM Verstegen, ... Nature 501 (7466), 227-231, 2013 | 294 | 2013 |
| Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping PJP De Vree, E De Wit, M Yilmaz, M Van De Heijning, P Klous, ... Nature biotechnology 32 (10), 1019-1025, 2014 | 292 | 2014 |
| YAP partially reprograms chromatin accessibility to directly induce adult cardiogenesis in vivo TO Monroe, MC Hill, Y Morikawa, JP Leach, T Heallen, S Cao, ... Developmental cell 48 (6), 765-779. e7, 2019 | 257 | 2019 |
| Enhancer hubs and loop collisions identified from single-allele topologies A Allahyar, C Vermeulen, BAM Bouwman, PHL Krijger, MJAM Verstegen, ... Nature genetics 50 (8), 1151-1160, 2018 | 229 | 2018 |
| Cell-of-origin-specific 3D genome structure acquired during somatic cell reprogramming PHL Krijger, B Di Stefano, E de Wit, F Limone, C Van Oevelen, W De Laat, ... Cell stem cell 18 (5), 597-610, 2016 | 216 | 2016 |
| A/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNAK164 modification P Langerak, AOH Nygren, PHL Krijger, P van den Berk, H Jacobs Journal of Experimental Medicine 204 (8), 1989-1998, 2007 | 186 | 2007 |
| 4C-seq from beginning to end: A detailed protocol for sample preparation and data analysis PHL Krijger, G Geeven, V Bianchi, CRE Hilvering, W de Laat Methods 170, 17-32, 2020 | 182 | 2020 |
| PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells A Hendel, PHL Krijger, N Diamant, Z Goren, P Langerak, J Kim, ... PLoS genetics 7 (9), e1002262, 2011 | 176 | 2011 |
| Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures X Wang, NR Tucker, G Rizki, R Mills, PHL Krijger, E de Wit, ... elife 5, e10557, 2016 | 123 | 2016 |
| Cause and consequence of tethering a SubTAD to different nuclear compartments PJ Wijchers, PHL Krijger, G Geeven, Y Zhu, A Denker, MJAM Verstegen, ... Molecular cell 61 (3), 461-473, 2016 | 103 | 2016 |
| Building regulatory landscapes reveals that an enhancer can recruit cohesin to create contact domains, engage CTCF sites and activate distant genes NJ Rinzema, K Sofiadis, SJD Tjalsma, MJAM Verstegen, Y Oz, ... Nature Structural & Molecular Biology 29 (6), 563-574, 2022 | 101 | 2022 |
| HLTF and SHPRH are not essential for PCNA polyubiquitination, survival and somatic hypermutation: existence of an alternative E3 ligase PHL Krijger, KY Lee, N Wit, PCM van den Berk, X Wu, HP Roest, A Maas, ... DNA repair 10 (4), 438-444, 2011 | 85 | 2011 |
| Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting NS Longo, PL Lugar, S Yavuz, W Zhang, PHL Krijger, DE Russ, DD Jima, ... Blood, The Journal of the American Society of Hematology 113 (16), 3706-3715, 2009 | 78 | 2009 |
| Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation PHL Krijger, P Langerak, PCM van den Berk, H Jacobs Journal of Experimental Medicine 206 (12), 2603-2611, 2009 | 64 | 2009 |
| PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance PHL Krijger, PCM van den Berk, N Wit, P Langerak, JG Jansen, ... DNA repair 10 (10), 1051-1059, 2011 | 63 | 2011 |
| Interplay between CTCF boundaries and a super enhancer controls cohesin extrusion trajectories and gene expression ESM Vos, C Valdes-Quezada, Y Huang, A Allahyar, MJAM Verstegen, ... Molecular cell 81 (15), 3082-3095. e6, 2021 | 48 | 2021 |
| Identical cells with different 3D genomes; cause and consequences? PHL Krijger, W de Laat Current opinion in genetics & development 23 (2), 191-196, 2013 | 47 | 2013 |
Elzo de WitNetherlands Cancer InstituteVerified email at nki.nl
