Javier A. Jaimes

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Gary WhittakerCornell UniversityVerified email at cornell.edu
Susan DanielFred H. Rhodes Professor of Chemical and Biomolecular Engineering, Cornell UniversityVerified email at cornell.edu
Jean K. MilletChargé de recherche, researcher at INRAEVerified email at inrae.fr
Miya Kristine BidonChemical & Biomolecular Engineering, Cornell UniversityVerified email at cornell.edu
Marco StrausCornell UniversityVerified email at cornell.edu
Joshua S. ChappieUSDA-ARSVerified email at usda.gov
Maureen Hoch Vieira FernandesStanford UniversityVerified email at stanford.edu
Luis Carlos Villamil-JiménezGrupo de Epidemiología y Salud Pública. Universidad de La SalleVerified email at unisalle.edu.co
Julian Ruiz-SaenzFacultad de Medicina veterinaria y Zootecnia - Universidad Cooperativa de ColombiaVerified email at campusucc.edu.co
Marlén Martínez-GutierrezUniversidad Cooperativa de Colombia-Universidad de AntioquiaVerified email at campusucc.edu.co
Lakshmi NathanCornell UniversityVerified email at cornell.edu
Hung-Lun HsuOxford Biomedica SolutionsVerified email at cornell.edu
My VT PhanArizona State UniversityVerified email at asu.edu
Santiago Rendon-MarinProfesor Facultad de Ciencias de la Vida. Programa de Medicina. Corporación Universitaria RemingtonVerified email at uniremington.edu.co
Diego G. DielPopulation Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell UniversityVerified email at cornell.edu
Diego Soler-TovarAssistant Professor, Faculty of Agricultural Sciences, Universidad de La Salle (Bogota, Colombia)Verified email at unisalle.edu.co
MARIA CRISTINA NAVAS NAVASProfessor, Faculty of Medicine, Universidad de AntioquiaVerified email at udea.edu.co
leonid yurkovetskiyUniversity of Massachusetts Medical SchoolVerified email at umassmed.edu
Jeremy LubanUMass Med, Broad Institute of MIT and Harvard, Ragon Institute of MGH, MIT, & Harvard; MassCPRVerified email at umassmed.edu
Lewis CantleyDana Farber Cancer Center and Harvard Medical SchoolVerified email at med.cornell.edu

Javier A. Jaimes

Senior Research Scientist - University of Massachusetts Medical School

Verified email at umassmed.edu - Homepage

virology viral pathogenesis virus evolution vaccines


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Coronavirus membrane fusion mechanism offers a potential target for antiviral development T Tang, M Bidon, JA Jaimes, GR Whittaker, S Daniel Antiviral research 178, 104792, 2020	869	2020
Phylogenetic analysis and structural modeling of SARS-CoV-2 spike protein reveals an evolutionary distinct and proteolytically sensitive activation loop JA Jaimes, NM André, JS Chappie, JK Millet, GR Whittaker Journal of molecular biology 432 (10), 3309-3325, 2020	540	2020
Proteolytic cleavage of the SARS-CoV-2 spike protein and the role of the novel S1/S2 site JA Jaimes, JK Millet, GR Whittaker IScience 23 (6), 101212, 2020	326	2020
Functional evaluation of the P681H mutation on the proteolytic activation the SARS-CoV-2 variant B. 1.1. 7 (Alpha) spike B Lubinski, MHV Fernandes, L Frazier, T Tang, S Daniel, DG Diel, ... iScience 25 (1), 103589, 2022	206*	2022
A Tale of Two Viruses: The Distinct Spike Glycoproteins of Feline Coronaviruses JA Jaimes, JK Millet, AE Stout, NM André, GR Whittaker Viruses 12 (1), 83, 2020	178	2020
Proteolytic activation of SARS-CoV-2 spike at the S1/S2 boundary: potential role of proteases beyond furin T Tang, JA Jaimes, MK Bidon, MR Straus, S Daniel, GR Whittaker ACS Infectious Diseases 7 (2), 264-271, 2021	157	2021
Coronaviruses in cats and other companion animals: Where does SARS-CoV-2/COVID-19 fit? AE Stout, NM André, JA Jaimes, JK Millet, GR Whittaker Veterinary microbiology 247, 108777, 2020	148	2020
Feline coronavirus: Insights into viral pathogenesis based on the spike protein structure and function JA Jaimes, GR Whittaker Virology 517, 108-121, 2018	127	2018
Molecular diversity of coronavirus host cell entry receptors JK Millet, JA Jaimes, GR Whittaker FEMS microbiology reviews 45 (3), fuaa057, 2021	126	2021
Inhibitors of L-type calcium channels show therapeutic potential for treating SARS-CoV-2 infections by preventing virus entry and spread MR Straus, MK Bidon, T Tang, JA Jaimes, GR Whittaker, S Daniel ACS Infectious Diseases, 2021	88*	2021
Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting JK Millet, T Tang, L Nathan, JA Jaimes, HL Hsu, S Daniel, GR Whittaker JoVE (Journal of Visualized Experiments), e59010, 2019	87	2019
Spike protein cleavage-activation in the context of the SARS-CoV-2 P681R mutation: an analysis from its first appearance in lineage A. 23.1 identified in Uganda B Lubinski, LE Frazier, MVT Phan, DL Bugembe, JL Cunningham, T Tang, ... Microbiology Spectrum, e01514-22, 2022	74*	2022
Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry ER Kastenhuber, M Mercadante, B Nilsson-Payant, JL Johnson, ... Elife 11, 2022	61	2022
Las enfermedades infecciosas y su importancia en el sector avícola JA Jaimes Olaya, AP Gómez Ramírez, DCM Álvarez Espejo, ... Revista de Medicina Veterinaria, 49-61, 2010	58	2010
Structural modeling of 2019-novel coronavirus (nCoV) spike protein reveals a proteolytically-sensitive activation loop as a distinguishing feature compared to SARS-CoV and … JA Jaimes, NM André, JK Millet, GR Whittaker arXiv preprint arXiv:2002.06196, 2020	50	2020
SARS-CoV-2 Clinical Outcome in Domestic and Wild Cats: A Systematic Review S Giraldo-Ramirez, S Rendon-Marin, JA Jaimes, M Martinez-Gutierrez, ... Animals 11 (7), 2056, 2021	45	2021
SARS-CoV-2 electrochemical immunosensor based on the spike-ACE2 complex V Vásquez, MC Navas, JA Jaimes, J Orozco Analytica chimica acta 1205, 339718, 2022	37	2022
Intrinsic furin-mediated cleavability of the spike S1/S2 site from SARS-CoV-2 variant B. 1.1. 529 (Omicron) B Lubinski, JA Jaimes, GR Whittaker BioRxiv, 2022.04. 20.488969, 2022	30	2022
SARS CoV-2 Spike protein in silico interaction with ACE2 receptors from wild and domestic species S Rendon-Marin, M Martinez-Gutierrez, GR Whittaker, JA Jaimes, ... Frontiers in Genetics 12 (27), 2021	29	2021
A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation JA Jaimes, JK Millet, ME Goldstein, GR Whittaker, MR Straus JoVE (Journal of Visualized Experiments), e58892, 2019	29	2019

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