| Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP axis P Rada, AI Rojo, N Evrard-Todeschi, NG Innamorato, A Cotte, T Jaworski, ... Molecular and cellular biology 32 (17), 3486-3499, 2012 | 381 | 2012 |
| Cytochromes P450 catalyze both steps of the major pathway of clopidogrel bioactivation, whereas paraoxonase catalyzes the formation of a minor thiol metabolite isomer PM Dansette, J Rosi, G Bertho, D Mansuy Chemical research in toxicology 25 (2), 348-356, 2012 | 141 | 2012 |
| Metabolic oxidative cleavage of thioesters: evidence for the formation of sulfenic acid intermediates in the bioactivation of the antithrombotic prodrugs ticlopidine and … PM Dansette, J Libraire, G Bertho, D Mansuy Chemical research in toxicology 22 (2), 369-373, 2009 | 103 | 2009 |
| The First Water‐Soluble Copper(I) Calix[6]arene Complex Presenting a Hydrophobic Ligand Binding Pocket: A Remarkable Model for Active Sites in Metalloenzymes Y Rondelez, G Bertho, O Reinaud Angewandte Chemie 114 (6), 1086-1088, 2002 | 99 | 2002 |
| First evidence that cytochrome P450 may catalyze both S-oxidation and epoxidation of thiophene derivatives PM Dansette, G Bertho, D Mansuy Biochemical and biophysical research communications 338 (1), 450-455, 2005 | 93 | 2005 |
| Automatic clustering of docking poses in virtual screening process using self-organizing map G Bouvier, N Evrard-Todeschi, JP Girault, G Bertho Bioinformatics 26 (1), 53-60, 2010 | 88 | 2010 |
| Identification and quantitative analysis of the phytoecdysteroids in Silene species (Caryophyllaceae) by high-performance liquid chromatography: Novel ecdysteroids from S … Y Meng, P Whiting, L Zibareva, G Bertho, JP Girault, R Lafont, L Dinan Journal of Chromatography A 935 (1-2), 309-319, 2001 | 77 | 2001 |
| Paraoxonase-1 and clopidogrel efficacy PM Dansette, J Rosi, G Bertho, D Mansuy Nature medicine 17 (9), 1040-1041, 2011 | 62 | 2011 |
| Tryptophan depletion and the kinase GCN2 mediate IFN-γ–induced autophagy S Fougeray, I Mami, G Bertho, P Beaune, E Thervet, N Pallet The Journal of immunology 189 (6), 2954-2964, 2012 | 57 | 2012 |
| Conformational analysis of ketolide, conformations of RU 004 in solution and bound to bacterial ribosomes G Bertho, J Gharbi-Benarous, M Delaforge, C Lang, A Parent, JP Girault Journal of medicinal chemistry 41 (18), 3373-3386, 1998 | 55 | 1998 |
| Specific physical exercise improves energetic metabolism in the skeletal muscle of amyotrophic-lateral-sclerosis mice C Desseille, S Deforges, O Biondi, L Houdebine, D D’amico, A Lamazière, ... Frontiers in Molecular Neuroscience 10, 332, 2017 | 54 | 2017 |
| NMR studies of the phosphorylation motif of the HIV-1 protein Vpu bound to the F-box protein β-TrCP G Coadou, J Gharbi-Benarous, S Megy, G Bertho, N Evrard-Todeschi, ... Biochemistry 42 (50), 14741-14751, 2003 | 54 | 2003 |
| Transferred nuclear Overhauser effect study of macrolide–ribosome interactions: correlation between antibiotic activities and bound conformations G Bertho, J Gharbi-Benarous, M Delaforge, JP Girault Bioorganic & medicinal chemistry 6 (2), 209-221, 1998 | 51 | 1998 |
| Sheep prion protein synthetic peptide spanning helix 1 and β-strand 2 (residues 142–166) shows β-hairpin structure in solution SA Kozin, G Bertho, AK Mazur, H Rabesona, JP Girault, T Haertlé, ... Journal of Biological Chemistry 276 (49), 46364-46370, 2001 | 49 | 2001 |
| Solution conformation of methylated macrolide antibiotics roxithromycin and erythromycin using NMR and molecular modelling. Ribosome-bound conformation determined by TRNOE and … G Bertho, P Ladam, J Gharbi-Benarous, M Delaforge, JP Girault International journal of biological macromolecules 22 (2), 103-127, 1998 | 46 | 1998 |
| Oxidative and Reductive Metabolism of Tris(p-carboxyltetrathiaaryl)methyl Radicals by Liver Microsomes C Decroos, Y Li, G Bertho, Y Frapart, D Mansuy, JL Boucher Chemical research in toxicology 22 (7), 1342-1350, 2009 | 45 | 2009 |
| Lincomycin and clindamycin conformations. A fragment shared by macrolides, ketolides and lincosamides determined from TRNOE ribosome-bound conformations L Verdier, G Bertho, J Gharbi-Benarous, JP Girault Bioorganic & medicinal chemistry 8 (6), 1225-1243, 2000 | 44 | 2000 |
| Contact-based ligand-clustering approach for the identification of active compounds in virtual screening AB Mantsyzov, G Bouvier, N Evrard-Todeschi, G Bertho Advances and Applications in Bioinformatics and Chemistry, 61-79, 2012 | 42 | 2012 |
| Conformations in solution and bound to bacterial ribosomes of ketolides, HMR 3647 (telithromycin) and RU 72366: A new class of highly potent antibacterials N Evrard-Todeschi, J Gharbi-Benarous, C Gaillet, L Verdier, G Bertho, ... Bioorganic & medicinal chemistry 8 (7), 1579-1597, 2000 | 38 | 2000 |
| Formation and fate of a sulfenic acid intermediate in the metabolic activation of the antithrombotic prodrug prasugrel PM Dansette, S Thébault, G Bertho, D Mansuy Chemical research in toxicology 23 (7), 1268-1274, 2010 | 37 | 2010 |
Guillaume BouvierInstitut PasteurVerified email at ens-cachan.org