Insulin receptor substrate-1 and phosphoinositide-dependent kinase-1 are required for insulin-stimulated production of nitric oxide in endothelial cells M Montagnani, LV Ravichandran, H Chen, DL Esposito, MJ Quon Molecular endocrinology 16 (8), 1931-1942, 2002 | 314 | 2002 |
Protein kinase C-ζ phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin LV Ravichandran, DL Esposito, J Chen, MJ Quon Journal of Biological Chemistry 276 (5), 3543-3549, 2001 | 273 | 2001 |
Signaling via the insulin-like growth factor-I receptor: does it differ from insulin receptor signaling? VA Blakesley, A Scrimgeour, D Esposito, D Le Roith Cytokine & growth factor reviews 7 (2), 153-159, 1996 | 260 | 1996 |
Tyr612 and Tyr632 in Human Insulin Receptor Substrate-1 Are Important for Full Activation of Insulin-Stimulated Phosphatidylinositol 3-Kinase Activity and … DL Esposito, Y Li, A Cama, MJ Quon Endocrinology 142 (7), 2833-2840, 2001 | 208 | 2001 |
APC gene mutations and colorectal adenomatosis in familial adenomatous polyposis F Ficari, A Cama, R Valanzano, MC Curia, R Palmirotta, G Aceto, ... British journal of cancer 82 (2), 348-353, 2000 | 142 | 2000 |
Interaction between the G1057D variant of IRS-2 and overweight in the pathogenesis of type 2 diabetes S Mammarella, F Romano, A Di Valerio, B Creati, DL Esposito, ... Human molecular genetics 9 (17), 2517-2521, 2000 | 125 | 2000 |
Different subcellular localization and phosphoinositides binding of insulin receptor substrate protein pleckstrin homology domains G Razzini, A Ingrosso, A Brancaccio, S Sciacchitano, DL Esposito, ... Molecular endocrinology 14 (6), 823-836, 2000 | 89 | 2000 |
Autophagy as an ultrastructural marker of heavy metal toxicity in human cord blood hematopoietic stem cells M Di Gioacchino, C Petrarca, A Perrone, M Farina, E Sabbioni, T Hartung, ... Science of the Total Environment 392 (1), 50-58, 2008 | 87 | 2008 |
The insulin receptor substrate 1 (IRS1) in intestinal epithelial differentiation and in colorectal cancer DL Esposito, F Aru, R Lattanzio, A Morgano, M Abbondanza, ... PloS one 7 (4), e36190, 2012 | 84 | 2012 |
A novel T608R missense mutation in insulin receptor substrate-1 identified in a subject with type 2 diabetes impairs metabolic insulin signaling DL Esposito, Y Li, C Vanni, S Mammarella, S Veschi, F Della Loggia, ... The Journal of Clinical Endocrinology & Metabolism 88 (4), 1468-1475, 2003 | 60 | 2003 |
Tyrosine residues in the C-terminal domain of the insulin-like growth factor-I receptor mediate mitogenic and tumorigenic signals DL Esposito, VA Blakesley, AP Koval, AG Scrimgeour, D LeRoith Endocrinology 138 (7), 2979-2988, 1997 | 59 | 1997 |
Patterns of K-ras mutation in colorectal carcinomas from Iran and Italy (a Gruppo Oncologico dell'Italia Meridionale study): influence of microsatellite instability status and … F Bishehsari, M Mahdavinia, R Malekzadeh, F Verginelli, T Catalano, ... Annals of oncology 17, vii91-vii96, 2006 | 58 | 2006 |
Alterations of microsatellites in neurofibromas of von Recklinghausen's disease L Ottini, DL Esposito, A Richetta, M Carlesimo, R Palmirotta, MC Verì, ... Cancer research 55 (23), 5677-5680, 1995 | 57 | 1995 |
Novel mutations and inactivation of both alleles of the APC gene in desmoid tumors R Palmirotta, MC Curia, DL Esposito, R Valanzano, L Messerini, F Ficari, ... Human molecular genetics 4 (10), 1979-1981, 1995 | 56 | 1995 |
PAX3/Forkhead Homolog in Rhabdomyosarcoma Oncoprotein Activates Glucose Transporter 4 Gene Expression in Vivo and in Vitro M Armoni, MJ Quon, G Maor, S Avigad, DN Shapiro, C Harel, D Esposito, ... The Journal of Clinical Endocrinology & Metabolism 87 (11), 5312-5324, 2002 | 47 | 2002 |
Autophagy in hematopoietic stem/progenitor cells exposed to heavy metals: biological implications and toxicological relevance M Di Gioacchino, C Petrarca, A Perrone, S Martino, DL Esposito, LV Lotti, ... Autophagy 4 (4), 537-539, 2008 | 42 | 2008 |
Expression and localisation of insulin receptor substrate 2 in normal intestine and colorectal tumours. Regulation by intestine-specific transcription factor CDX2 S Modica, A Morgano, L Salvatore, M Petruzzelli, MT Vanier, R Valanzano, ... Gut 58 (9), 1250-1259, 2009 | 31 | 2009 |
Multiplex PCR analysis and genotype–phenotype correlations of frequent APC mutations A Cama, R Palmirotta, MC Curia, DL Esposito, A Ranieri, F Ficari, ... Human mutation 5 (2), 144-152, 1995 | 31 | 1995 |
p53 expression and genetic evidence for viral infection in intraepithelial neoplasia of the uterine cervix A Vecchione, C Cermele, MR Giovagnoli, C Valli, M Alimandi, E Carico, ... Gynecologic oncology 55 (3), 343-348, 1994 | 30 | 1994 |
Transcript dosage effect in familial adenomatous polyposis: Model offered by two kindreds with exon 9 APC gene mutations MC Curia, DL Esposito, G Aceto, R Palmirotta, S Crognale, R Valanzano, ... Human mutation 11 (3), 197-201, 1998 | 29 | 1998 |