Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging AM Dickens, SW Yoo, AC Chin, J Xu, TP Johnson, AL Trout, KF Hauser, ... Scientific reports 7 (1), 7748, 2017 | 96 | 2017 |
Neuroinflammation and the cGAS-STING pathway AC Chin Journal of neurophysiology 121 (4), 1087-1091, 2019 | 63 | 2019 |
Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via α-actinin and focal adhesion kinase C Fu, J Xu, W Cheng, T Rojas, AC Chin, AM Snowman, MM Harraz, ... Proceedings of the National Academy of Sciences 114 (8), 2036-2041, 2017 | 51 | 2017 |
Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1 C Fu, T Rojas, AC Chin, W Cheng, IA Bernstein, LK Albacarys, WW Wright, ... Scientific reports 8 (1), 7039, 2018 | 25 | 2018 |
The inositol pyrophosphate 5-InsP7 drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α AC Chin, Z Gao, AM Riley, D Furkert, C Wittwer, A Dutta, T Rojas, ... Science Advances 6 (44), eabb8542, 2020 | 24 | 2020 |
Inositol polyphosphate multikinase inhibits angiogenesis via inositol pentakisphosphate-induced HIF-1α degradation C Fu, R Tyagi, AC Chin, T Rojas, RJ Li, P Guha, IA Bernstein, F Rao, R Xu, ... Circulation research 122 (3), 457-472, 2018 | 22 | 2018 |
D-Serine Potently Drives Ligand-Binding Domain Closure in the Ionotropic Glutamate Receptor GluD2 AC Chin, RA Yovanno, TJ Wied, A Gershman, AY Lau Structure 28 (10), 1168-1178. e2, 2020 | 19 | 2020 |
Inositol hexakisphosphate kinase 3 promotes focal adhesion turnover via interactions with dynein intermediate chain 2 T Rojas, W Cheng, Z Gao, X Liu, Y Wang, AP Malla, AC Chin, LH Romer, ... Proceedings of the National Academy of Sciences 116 (8), 3278-3287, 2019 | 17 | 2019 |
Self-reported health without clinically measurable benefits among adult users of multivitamin and multimineral supplements: a cross-sectional study MD Paranjpe, AC Chin, I Paranjpe, NJ Reid, PQ Duy, JK Wang, ... BMJ open 10 (11), e039119, 2020 | 16 | 2020 |
PERK-STING Signaling Drives Neuroinflammation in Traumatic Brain Injury AC Chin Journal of Neuroscience 40 (12), 2384-2386, 2020 | 14 | 2020 |
Itraconazole inhibits endothelial cell migration by disrupting inositol pyrophosphate-dependent focal adhesion dynamics and cytoskeletal remodeling J Qi, W Cheng, Z Gao, Y Chen, ML Shipton, D Furkert, AC Chin, AM Riley, ... Biomedicine & Pharmacotherapy 161, 114449, 2023 | 11 | 2023 |
High Conformational Variability in the GluK2 Kainate Receptor Ligand-Binding Domain TJ Wied, AC Chin, AY Lau Structure 27 (1), 189-195. e2, 2019 | 9 | 2019 |
Blockchain Biology AC Chin Frontiers in Blockchain 3, 606413, 2020 | 5 | 2020 |
Depleting inositol pyrophosphate 5-InsP7 protected the heart against ischaemia–reperfusion injury by elevating plasma adiponectin L Fu, J Du, D Furkert, ML Shipton, X Liu, T Aguirre, AC Chin, AM Riley, ... Cardiovascular Research, cvae017, 2024 | 4 | 2024 |
Myosin modulators move forward with FDA approval of mavacamten AC Chin, SM Day Nature Cardiovascular Research 1 (7), 595-596, 2022 | 4 | 2022 |
Structural biology and thermodynamics of GluD receptors AC Chin, AY Lau Neuropharmacology 191, 108542, 2021 | 4 | 2021 |
Methotrexate for gestational choriocarcinoma: a paradigm shift in oncology AC Chin Nature Reviews Endocrinology 19 (9), 501-501, 2023 | 3 | 2023 |
Inhibiting IP6K1 confers atheroprotection by elevating circulating apolipoprotein AI X Liu, Z Zhang, T Aguirre, ML Shipton, L Fu, J Du, D Furkert, J Qi, AC Chin, ... Metabolism 163, 156098, 2025 | 1 | 2025 |
IP6K1 rewires LKB1 signaling to mediate hyperglycemic endothelial senescence C Xing, L Shi, L Zhu, T Aguirre, J Qi, Y Chen, Y Liu, AC Chin, H Zhu, ... Diabetes, db240706, 2025 | | 2025 |
Deleting IP6K1 stabilizes neuronal sodium–potassium pumps and suppresses excitability H Jin, A Liu, AC Chin, C Fu, H Shen, W Cheng Molecular Brain 17 (1), 8, 2024 | | 2024 |