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Xiaohua Ye
Xiaohua Ye
Westlake University
Verified email at westlake.edu.cn
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Year
Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape
Z Ku, X Xie, E Davidson, X Ye, H Su, VD Menachery, Y Li, Z Yuan, ...
Nature communications 12 (1), 469, 2021
1632021
Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants
Z Ku, X Xie, PR Hinton, X Liu, X Ye, AE Muruato, DC Ng, S Biswas, J Zou, ...
Nature 595 (7869), 718-723, 2021
1472021
A virus-like particle based bivalent vaccine confers dual protection against enterovirus 71 and coxsackievirus A16 infections in mice
Z Ku, Q Liu, X Ye, Y Cai, X Wang, J Shi, D Li, X Jin, W An, Z Huang
Vaccine 32 (34), 4296-4303, 2014
872014
Neutralizing antibodies induced by recombinant virus-like particles of enterovirus 71 genotype C4 inhibit infection at pre-and post-attachment steps
Z Ku, X Ye, X Huang, Y Cai, Q Liu, Y Li, Z Su, Z Huang
PLoS One 8 (2), e57601, 2013
802013
Chimeric virus-like particle vaccines displaying conserved enterovirus 71 epitopes elicit protective neutralizing antibodies in mice through divergent mechanisms
X Ye, Z Ku, Q Liu, X Wang, J Shi, Y Zhang, L Kong, Y Cong, Z Huang
Journal of virology 88 (1), 72-81, 2014
762014
High-yield production of recombinant virus-like particles of enterovirus 71 in Pichia pastoris and their protective efficacy against oral viral challenge in mice
C Zhang, Z Ku, Q Liu, X Wang, T Chen, X Ye, D Li, X Jin, Z Huang
Vaccine 33 (20), 2335-2341, 2015
742015
A virus-like particle-based tetravalent vaccine for hand, foot, and mouth disease elicits broad and balanced protective immunity
W Zhang, W Dai, C Zhang, Y Zhou, P Xiong, S Wang, X Ye, Q Liu, D Zhou, ...
Emerging Microbes & Infections 7 (1), 1-12, 2018
622018
A modular vaccine development platform based on sortase-mediated site-specific tagging of antigens onto virus-like particles
S Tang, B Xuan, X Ye, Z Huang, Z Qian
Scientific reports 6 (1), 25741, 2016
542016
Single neutralizing monoclonal antibodies targeting the VP1 GH loop of enterovirus 71 inhibit both virus attachment and internalization during viral entry
Z Ku, X Ye, J Shi, X Wang, Q Liu, Z Huang
Journal of Virology 89 (23), 12084-12095, 2015
542015
Transcutaneous immunization via rapidly dissolvable microneedles protects against hand-foot-and-mouth disease caused by enterovirus 71
Z Zhu, X Ye, Z Ku, Q Liu, C Shen, H Luo, H Luan, C Zhang, S Tian, ...
Journal of Controlled Release 243, 291-302, 2016
532016
Structural basis for recognition of human enterovirus 71 by a bivalent broadly neutralizing monoclonal antibody
X Ye, C Fan, Z Ku, T Zuo, L Kong, C Zhang, J Shi, Q Liu, T Chen, Y Zhang, ...
PLoS pathogens 12 (3), e1005454, 2016
512016
A replication-defective human cytomegalovirus vaccine elicits humoral immune responses analogous to those with natural infection
Y Liu, DC Freed, L Li, A Tang, F Li, EM Murray, SP Adler, MA McVoy, ...
Journal of virology 93 (23), 10.1128/jvi. 00747-19, 2019
462019
A bivalent virus-like particle based vaccine induces a balanced antibody response against both enterovirus 71 and norovirus in mice
X Wang, Z Ku, W Dai, T Chen, X Ye, C Zhang, Y Zhang, Q Liu, X Jin, ...
Vaccine 33 (43), 5779-5785, 2015
362015
Coxsackievirus A10 atomic structure facilitating the discovery of a broad-spectrum inhibitor against human enteroviruses
J Chen, X Ye, XY Zhang, Z Zhu, X Zhang, Z Xu, Z Ding, G Zou, Q Liu, ...
Cell discovery 5 (1), 4, 2019
352019
Beta-propiolactone inactivation of coxsackievirus A16 induces structural alteration and surface modification of viral capsids
C Fan, X Ye, Z Ku, L Kong, Q Liu, C Xu, Y Cong, Z Huang
Journal of virology 91 (8), 10.1128/jvi. 00038-17, 2017
352017
Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth
Z Ku, X Xie, J Lin, P Gao, B Wu, A El Sahili, H Su, Y Liu, X Ye, EY Tan, ...
Nature communications 13 (1), 5552, 2022
332022
Coxsackievirus A16-like particles produced in Pichia pastoris elicit high-titer neutralizing antibodies and confer protection against lethal viral challenge in mice
C Zhang, Q Liu, Z Ku, Y Hu, X Ye, Y Zhang, Z Huang
Antiviral Research 129, 47-51, 2016
322016
Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step
X Ye, H Su, D Wrapp, DC Freed, F Li, Z Yuan, A Tang, L Li, Z Ku, W Xiong, ...
PLoS pathogens 16 (8), e1008736, 2020
282020
Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies
D Wrapp, X Ye, Z Ku, H Su, HG Jones, N Wang, AK Mishra, DC Freed, ...
Science advances 8 (10), eabm2546, 2022
272022
Inactivated coxsackievirus A10 experimental vaccines protect mice against lethal viral challenge
C Shen, Q Liu, Y Zhou, Z Ku, L Wang, K Lan, X Ye, Z Huang
Vaccine 34 (41), 5005-5012, 2016
272016
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