Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells KE Richards, AE Zeleniak, ML Fishel, J Wu, LE Littlepage, R Hill Oncogene 36 (13), 1770-1778, 2017 | 763 | 2017 |
The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target ML Fishel, MR Kelley Molecular aspects of medicine 28 (3-4), 375-395, 2007 | 340 | 2007 |
DNA repair in neurons: so if they don’t divide what's to repair? ML Fishel, MR Vasko, MR Kelley Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 614 (1 …, 2007 | 306 | 2007 |
STAT3 in the systemic inflammation of cancer cachexia TA Zimmers, ML Fishel, A Bonetto Seminars in cell & developmental biology 54, 28-41, 2016 | 249 | 2016 |
Targeting DNA repair pathways for cancer treatment: what’s new? MR Kelley, D Logsdon, ML Fishel Future Oncology 10 (7), 1215-1237, 2014 | 234 | 2014 |
APE1/Ref-1role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1 M R Kelley, M M Georgiadis, M L Fishel Current molecular pharmacology 5 (1), 36-53, 2012 | 202 | 2012 |
Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1 M Luo, S Delaplane, A Jiang, A Reed, Y He, M Fishel, RL Nyland, ... Antioxidants & redox signaling 10 (11), 1853-1867, 2008 | 201 | 2008 |
Manipulation of base excision repair to sensitize ovarian cancer cells to alkylating agent temozolomide ML Fishel, Y He, ML Smith, MR Kelley Clinical cancer research 13 (1), 260-267, 2007 | 175 | 2007 |
Implication of p53 in base excision DNA repair: in vivo evidence YR Seo, ML Fishel, S Amundson, MR Kelley, ML Smith Oncogene 21 (5), 731-737, 2002 | 154 | 2002 |
Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic F Shah, D Logsdon, RA Messmann, JC Fehrenbacher, ML Fishel, ... NPJ precision oncology 1 (1), 19, 2017 | 139 | 2017 |
DNA repair proteins as molecular targets for cancer therapeutics MR Kelley, ML Fishel Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2008 | 138 | 2008 |
Going ape as an approach to cancer therapeutics A Bapat, ML Fishel, MR Kelley Antioxidants & redox signaling 11 (3), 651-667, 2009 | 135 | 2009 |
Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth ML Fishel, Y Jiang, NV Rajeshkumar, G Scandura, AL Sinn, Y He, C Shen, ... Molecular cancer therapeutics 10 (9), 1698-1708, 2011 | 133 | 2011 |
Refining colorectal cancer classification and clinical stratification through a single-cell atlas AM Khaliq, C Erdogan, Z Kurt, SS Turgut, MW Grunvald, T Rand, S Khare, ... Genome biology 23 (1), 113, 2022 | 126 | 2022 |
APE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1–STAT3 dual-targeting effectively inhibits pancreatic cancer cell survival AA Cardoso, Y Jiang, M Luo, AM Reed, S Shahda, Y He, A Maitra, ... Public Library of Science 7 (10), e47462, 2012 | 125 | 2012 |
Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth ML Fishel, Y He, AM Reed, H Chin-Sinex, GD Hutchins, MS Mendonca, ... DNA repair 7 (2), 177-186, 2008 | 122 | 2008 |
Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells A Bapat, LTS Glass, M Luo, ML Fishel, EC Long, MM Georgiadis, ... Journal of Pharmacology and Experimental Therapeutics 334 (3), 988-998, 2010 | 118 | 2010 |
Regulation of HIF1α under hypoxia by APE1/Ref-1 impacts CA9 expression: dual targeting in patient-derived 3D pancreatic cancer models DP Logsdon, M Grimard, M Luo, S Shahda, Y Jiang, Y Tong, Z Yu, ... Molecular cancer therapeutics 15 (11), 2722-2732, 2016 | 116 | 2016 |
A graph neural network model to estimate cell-wise metabolic flux using single-cell RNA-seq data N Alghamdi, W Chang, P Dang, X Lu, C Wan, S Gampala, Z Huang, ... Genome research 31 (10), 1867-1884, 2021 | 110 | 2021 |
Long-term gemcitabine treatment reshapes the pancreatic tumor microenvironment and sensitizes murine carcinoma to combination immunotherapy DR Principe, M Narbutis, S Kumar, A Park, N Viswakarma, MJ Dorman, ... Cancer research 80 (15), 3101-3115, 2020 | 104 | 2020 |