Bringing new life to damaged bone: the importance of angiogenesis in bone repair and regeneration S Stegen, N Van Gastel, G Carmeliet Bone 70, 19-27, 2015 | 482 | 2015 |
Uncovering the periosteum for skeletal regeneration: the stem cell that lies beneath SJ Roberts, N Van Gastel, G Carmeliet, FP Luyten Bone 70, 10-18, 2015 | 262 | 2015 |
C9orf72 suppresses systemic and neural inflammation induced by gut bacteria A Burberry, MF Wells, F Limone, A Couto, KS Smith, J Keaney, G Gillet, ... Nature 582 (7810), 89-94, 2020 | 260 | 2020 |
Lipid availability determines fate of skeletal progenitor cells via SOX9 N Van Gastel, S Stegen, G Eelen, S Schoors, A Carlier, VW Daniëls, ... Nature 579 (7797), 111-117, 2020 | 197 | 2020 |
HIF-1α promotes glutamine-mediated redox homeostasis and glycogen-dependent bioenergetics to support postimplantation bone cell survival S Stegen, N Van Gastel, G Eelen, B Ghesquière, F D’Anna, B Thienpont, ... Cell metabolism 23 (2), 265-279, 2016 | 182 | 2016 |
Engineering vascularized bone: osteogenic and proangiogenic potential of murine periosteal cells N Van Gastel, S Torrekens, SJ Roberts, K Moermans, J Schrooten, ... Stem cells 30 (11), 2460-2471, 2012 | 132 | 2012 |
Induction of a timed metabolic collapse to overcome cancer chemoresistance N Van Gastel, JB Spinelli, A Sharda, A Schajnovitz, N Baryawno, C Rhee, ... Cell Metabolism 32 (3), 391-403. e6, 2020 | 129 | 2020 |
Mechanisms of ectopic bone formation by human osteoprogenitor cells on CaP biomaterial carriers YC Chai, SJ Roberts, E Desmet, G Kerckhofs, N van Gastel, L Geris, ... Biomaterials 33 (11), 3127-3142, 2012 | 122 | 2012 |
Development of micro-CT protocols for in vivo follow-up of mouse bone architecture without major radiation side effects K Laperre, M Depypere, N Van Gastel, S Torrekens, K Moermans, ... Bone 49 (4), 613-622, 2011 | 113 | 2011 |
Metabolic regulation of skeletal cell fate and function in physiology and disease N Van Gastel, G Carmeliet Nature Metabolism 3 (1), 11-20, 2021 | 104 | 2021 |
Simultaneous three-dimensional visualization of mineralized and soft skeletal tissues by a novel microCT contrast agent with polyoxometalate structure G Kerckhofs, S Stegen, N van Gastel, A Sap, G Falgayrac, G Penel, ... Biomaterials 159, 1-12, 2018 | 100 | 2018 |
Oxygen as a critical determinant of bone fracture healing—a multiscale model A Carlier, L Geris, N Van Gastel, G Carmeliet, H Van Oosterwyck Journal of theoretical biology 365, 247-264, 2015 | 100 | 2015 |
Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways JK Manesia, Z Xu, D Broekaert, R Boon, A van Vliet, G Eelen, ... Stem cell research 15 (3), 715-721, 2015 | 94 | 2015 |
Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers RZ Yusuf, B Saez, A Sharda, N Van Gastel, VWC Yu, N Baryawno, ... Blood, The Journal of the American Society of Hematology 136 (11), 1303-1316, 2020 | 91 | 2020 |
Expansion of murine periosteal progenitor cells with fibroblast growth factor 2 reveals an intrinsic endochondral ossification program mediated by bone morphogenetic protein 2 N Van Gastel, S Stegen, I Stockmans, K Moermans, J Schrooten, D Graf, ... Stem cells 32 (9), 2407-2418, 2014 | 78 | 2014 |
Size Does Matter: An Integrative In Vivo-In Silico Approach for the Treatment of Critical Size Bone Defects A Carlier, N Van Gastel, L Geris, G Carmeliet, H Van Oosterwyck PLoS computational biology 10 (11), e1003888, 2014 | 55 | 2014 |
Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis YP Wang, A Sharda, SN Xu, N Van Gastel, CH Man, U Choi, WZ Leong, ... Cell metabolism 33 (5), 1027-1041. e8, 2021 | 54 | 2021 |
Targeting the hypoxic response in bone tissue engineering: a balance between supply and consumption to improve bone regeneration PJ Stiers, N Van Gastel, G Carmeliet Molecular and cellular endocrinology 432, 96-105, 2016 | 44 | 2016 |
Nestin-GFP transgene labels skeletal progenitors in the periosteum G Tournaire, S Stegen, G Giacomini, I Stockmans, K Moermans, ... Bone 133, 115259, 2020 | 43 | 2020 |
The vasculature: a vessel for bone metastasis K Raymaekers, S Stegen, N Van Gastel, G Carmeliet BoneKEy reports 4, 2015 | 42 | 2015 |