| Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease A Ghosh, A Roy, X Liu, JH Kordower, EJ Mufson, DM Hartley, S Ghosh, ... Proceedings of the National Academy of Sciences 104 (47), 18754-18759, 2007 | 528 | 2007 |
| Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes H Jin, A Kanthasamy, A Ghosh, V Anantharam, B Kalyanaraman, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (8 …, 2014 | 407 | 2014 |
| Neuroprotection by a mitochondria-targeted drug in a Parkinson's disease model A Ghosh, K Chandran, SV Kalivendi, J Joseph, WE Antholine, CJ Hillard, ... Free Radical Biology and Medicine 49 (11), 1674-1684, 2010 | 224 | 2010 |
| α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity H Jin, A Kanthasamy, A Ghosh, Y Yang, V Anantharam, AG Kanthasamy Journal of Neuroscience 31 (6), 2035-2051, 2011 | 210 | 2011 |
| Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease A Ghosh, A Roy, J Matras, S Brahmachari, HE Gendelman, K Pahan Journal of Neuroscience 29 (43), 13543-13556, 2009 | 202 | 2009 |
| Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson’s disease A Ghosh, T Tyson, S George, EN Hildebrandt, JA Steiner, Z Madaj, ... Science translational medicine 8 (368), 368ra174-368ra174, 2016 | 169 | 2016 |
| Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson’s disease A Roy, A Ghosh, A Jana, X Liu, S Brahmachari, HE Gendelman, K Pahan PloS one 7 (6), e38113, 2012 | 146 | 2012 |
| Manganese exposure induces neuroinflammation by impairing mitochondrial dynamics in astrocytes S Sarkar, E Malovic, DS Harischandra, HA Ngwa, A Ghosh, C Hogan, ... Neurotoxicology 64, 204-218, 2018 | 142 | 2018 |
| Anti-inflammatory and neuroprotective effects of an orally active apocynin derivative in pre-clinical models of Parkinson’s disease A Ghosh, A Kanthasamy, J Joseph, V Anantharam, P Srivastava, ... Journal of neuroinflammation 9, 1-16, 2012 | 135 | 2012 |
| Mito-apocynin prevents mitochondrial dysfunction, microglial activation, oxidative damage, and progressive neurodegeneration in MitoPark transgenic mice M Langley, A Ghosh, A Charli, S Sarkar, M Ay, J Luo, J Zielonka, T Brenza, ... Antioxidants & redox signaling 27 (14), 1048-1066, 2017 | 125 | 2017 |
| Mitoapocynin treatment protects against neuroinflammation and dopaminergic neurodegeneration in a preclinical animal model of Parkinson’s disease A Ghosh, MR Langley, DS Harischandra, ML Neal, H Jin, V Anantharam, ... Journal of Neuroimmune Pharmacology 11, 259-278, 2016 | 107 | 2016 |
| An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer’s disease A Ghosh, MM Comerota, D Wan, F Chen, NE Propson, SH Hwang, ... Science translational medicine 12 (573), eabb1206, 2020 | 102 | 2020 |
| Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease R Gordon, N Singh, V Lawana, A Ghosh, DS Harischandra, H Jin, ... Neurobiology of disease 93, 96-114, 2016 | 101 | 2016 |
| Progressive nigrostriatal terminal dysfunction and degeneration in the engrailed1 heterozygous mouse model of Parkinson's disease U Nordström, G Beauvais, A Ghosh, BCP Sasidharan, M Lundblad, ... Neurobiology of disease 73, 70-82, 2015 | 98 | 2015 |
| Methamphetamine-induced neurotoxicity linked to ubiquitin-proteasome system dysfunction and autophagy-related changes that can be modulated by protein kinase C delta in … M Lin, P Chandramani-Shivalingappa, H Jin, A Ghosh, V Anantharam, ... Neuroscience 210, 308-332, 2012 | 98 | 2012 |
| The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease A Ghosh, H Saminathan, A Kanthasamy, V Anantharam, H Jin, ... Journal of Biological Chemistry 288 (30), 21955-21971, 2013 | 95 | 2013 |
| Histone hyperacetylation up-regulates protein kinase Cδ in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease H Jin, A Kanthasamy, DS Harischandra, N Kondru, A Ghosh, N Panicker, ... Journal of Biological Chemistry 289 (50), 34743-34767, 2014 | 90 | 2014 |
| Clusterin secreted from astrocyte promotes excitatory synaptic transmission and ameliorates Alzheimer’s disease neuropathology F Chen, DB Swartzlander, A Ghosh, JD Fryer, B Wang, H Zheng Molecular neurodegeneration 16, 1-16, 2021 | 83 | 2021 |
| TNF-α preconditioning protects neurons via neuron-specific up-regulation of CREB-binding protein RN Saha, A Ghosh, CA Palencia, YK Fung, SM Dudek, K Pahan The Journal of immunology 183 (3), 2068-2078, 2009 | 76 | 2009 |
| Castration induces Parkinson disease pathologies in young male mice via inducible nitric-oxide synthase S Khasnavis, A Ghosh, A Roy, K Pahan Journal of Biological Chemistry 288 (29), 20843-20855, 2013 | 71 | 2013 |
Vellareddy AnantharamAssociate Professor of Biomedical Sciences, Iowa State UniversityVerified email at iastate.edu