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Riley E Perszyk
Riley E Perszyk
Verified email at emory.edu
Title
Cited by
Cited by
Year
Structure, function, and allosteric modulation of NMDA receptors
KB Hansen, F Yi, RE Perszyk, H Furukawa, LP Wollmuth, AJ Gibb, ...
Journal of General Physiology 150 (8), 1081-1105, 2018
5712018
Structure, function, and pharmacology of glutamate receptor ion channels
KB Hansen, LP Wollmuth, D Bowie, H Furukawa, FS Menniti, ...
Pharmacological Reviews 73 (4), 298-487, 2021
4362021
NMDA receptors in the central nervous system
KB Hansen, F Yi, RE Perszyk, FS Menniti, SF Traynelis
NMDA Receptors, 1-80, 2017
1872017
GluN2D-containing N-methyl-d-aspartate receptors mediate synaptic transmission in hippocampal interneurons and regulate interneuron activity
RE Perszyk, JO DiRaddo, KL Strong, CM Low, KK Ogden, A Khatri, ...
Molecular pharmacology 90 (6), 689-702, 2016
1012016
Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-D-aspartate receptors
KB Hansen, N Tajima, R Risgaard, RE Perszyk, L Jørgensen, KM Vance, ...
Molecular pharmacology 84 (1), 114-127, 2013
932013
Biased modulators of NMDA receptors control channel opening and ion selectivity
RE Perszyk, SA Swanger, C Shelley, A Khatri, G Fernandez-Cuervo, ...
Nature chemical biology 16 (2), 188-196, 2020
402020
An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups
R Perszyk, BM Katzman, H Kusumoto, SA Kell, MP Epplin, YA Tahirovic, ...
Elife 7, e34711, 2018
402018
Adolescent cocaine exposure simplifies orbitofrontal cortical dendritic arbors
LM DePoy, RE Perszyk, KS Zimmermann, AJ Koleske, SL Gourley
Frontiers in pharmacology 5, 228, 2014
262014
Hodgkin–Huxley–Katz Prize Lecture: Genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif
RE Perszyk, SJ Myers, H Yuan, AJ Gibb, H Furukawa, AI Sobolevsky, ...
The Journal of physiology 598 (15), 3071-3083, 2020
232020
A novel class of negative allosteric modulators of NMDA receptor function
BM Katzman, RE Perszyk, H Yuan, YA Tahirovic, AE Sotimehin, ...
Bioorganic & medicinal chemistry letters 25 (23), 5583-5588, 2015
222015
Three-dimensional missense tolerance ratio analysis
RE Perszyk, AS Kristensen, P Lyuboslavsky, SF Traynelis
Genome Research 31 (8), 1447-1461, 2021
212021
Opportunities for precision treatment of GRIN2A and GRIN2B gain-of-function variants in triheteromeric NMDA receptors
W Han, H Yuan, JP Allen, S Kim, GH Shaulsky, RE Perszyk, SF Traynelis, ...
Journal of Pharmacology and Experimental Therapeutics, 2022
132022
The Negative Allosteric Modulator EU1794-4 Reduces Single-Channel Conductance and Ca2+ Permeability of GluN1/GluN2A N-Methyl-d-Aspartate Receptors
RE Perszyk, Z Zheng, TG Banke, J Zhang, L Xie, MJ McDaniel, ...
Molecular Pharmacology 99 (5), 399-411, 2021
122021
Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate Receptors
KL Strong, MP Epplin, KK Ogden, PB Burger, TM Kaiser, TJ Wilding, ...
ACS chemical neuroscience 12 (1), 79-98, 2020
112020
Automated intracellular pharmacological electrophysiology for ligand-gated ionotropic receptor and pharmacology screening
RE Perszyk, MC Yip, OL McConnell, ET Wang, A Jenkins, SF Traynelis, ...
Molecular Pharmacology 100 (1), 73-82, 2021
72021
The GluN2A subunit of the NMDA receptor modulates the rate of functional maturation in parvalbumin-positive interneurons
CR Camp, L Shapiro, A Vlachos, RE Perszyk, N Shariatzadeh, J White, ...
bioRxiv, 2021
2021
Hodgkin-huxley-katz prize lecture: genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif (vol 598, pg 3071, 2020)
RE Perszyk, SJ Myers, H Yuan, AJ Gibb, H Furukawa, A Sobolevsky, ...
JOURNAL OF PHYSIOLOGY-LONDON 598 (21), 4995-4995, 2020
2020
Channel Open Probability Controls Allosteric Modulation of Potency and Efficacy
RE Perszyk, KK Ogden, KL Strong, DC Liotta, SF Traynelis
Biophysical Journal 112 (3), 420a-421a, 2017
2017
A conserved Asparagine Between Loops A and E of Anion Ligand-Gated Channels is Critical for Gaba (A) Receptor Function
REA Perszyk, CA Wiliams, A Jenkins
Biophysical Journal 100 (3), 271a, 2011
2011
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Articles 1–19