| Codeine intoxication associated with ultrarapid CYP2D6 metabolism Y Gasche, Y Daali, M Fathi, A Chiappe, S Cottini, P Dayer, J Desmeules New England Journal of Medicine 351 (27), 2827-2831, 2004 | 842 | 2004 |
| Applications of CYP450 testing in the clinical setting CF Samer, KI Lorenzini, V Rollason, Y Daali, JA Desmeules Molecular diagnosis & therapy 17, 165-184, 2013 | 488 | 2013 |
| Why has model‐informed precision dosing not yet become common clinical reality? Lessons from the past and a roadmap for the future AS Darwich, K Ogungbenro, AA Vinks, JR Powell, JL Reny, N Marsousi, ... Clinical Pharmacology & Therapeutics 101 (5), 646-656, 2017 | 237 | 2017 |
| Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety CF Samer, Y Daali, M Wagner, G Hopfgartner, CB Eap, MC Rebsamen, ... British journal of pharmacology 160 (4), 919-930, 2010 | 234 | 2010 |
| Analgesics in patients with hepatic impairment: pharmacology and clinical implications M Bosilkovska, B Walder, M Besson, Y Daali, J Desmeules Drugs 72, 1645-1669, 2012 | 233 | 2012 |
| The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone CF Samer, Y Daali, M Wagner, G Hopfgartner, CB Eap, MC Rebsamen, ... British journal of pharmacology 160 (4), 907-918, 2010 | 190 | 2010 |
| Geneva cocktail for cytochrome p450 and P‐glycoprotein activity assessment using dried blood spots M Bosilkovska, CF Samer, J Déglon, M Rebsamen, C Staub, P Dayer, ... ClInICAl PhArMACologY & TherAPeuTICS 96 (3), 349-359, 2014 | 164 | 2014 |
| The AmpliChip CYP450 test: cytochrome P450 2D6 genotype assessment and phenotype prediction MC Rebsamen, J Desmeules, Y Daali, A Chiappe, A Diemand, C Rey, ... The pharmacogenomics journal 9 (1), 34-41, 2009 | 152 | 2009 |
| Model-informed precision dosing: background, requirements, validation, implementation, and forward trajectory of individualizing drug therapy AS Darwich, TM Polasek, JK Aronson, K Ogungbenro, DFB Wright, ... Annual review of pharmacology and toxicology 61 (1), 225-245, 2021 | 140 | 2021 |
| NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion N Li, B Li, T Brun, C Deffert-Delbouille, Z Mahiout, Y Daali, XJ Ma, ... Diabetes 61 (11), 2842-2850, 2012 | 134 | 2012 |
| Mesoporous silica nanoparticles as pH-responsive carrier for the immune-activating drug resiquimod enhance the local immune response in mice J Wagner, D Gößl, N Ustyanovska, M Xiong, D Hauser, O Zhuzhgova, ... ACS nano 15 (3), 4450-4466, 2021 | 128 | 2021 |
| A cocktail approach for assessing the in vitro activity of human cytochrome P450s: an overview of current methodologies D Spaggiari, L Geiser, Y Daali, S Rudaz Journal of pharmaceutical and biomedical analysis 101, 221-237, 2014 | 124 | 2014 |
| Antiplatelet Therapy: Targeting the TxA2 Pathway P Fontana, A Zufferey, Y Daali, JL Reny Journal of cardiovascular translational research 7, 29-38, 2014 | 118 | 2014 |
| HZ166, a novel GABAA receptor subtype-selective benzodiazepine site ligand, is antihyperalgesic in mouse models of inflammatory and neuropathic pain A Di Lio, D Benke, M Besson, J Desmeules, Y Daali, Z Wang, R Edwankar, ... Neuropharmacology 60 (4), 626-632, 2011 | 114 | 2011 |
| Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite J Déglon, A Thomas, Y Daali, E Lauer, C Samer, J Desmeules, P Dayer, ... Journal of pharmaceutical and biomedical analysis 54 (2), 359-367, 2011 | 102 | 2011 |
| A simplified analytical method for a phenotyping cocktail of major CYP450 biotransformation routes MC Jerdi, Y Daali, MK Oestreicher, S Cherkaoui, P Dayer Journal of pharmaceutical and biomedical analysis 35 (5), 1203-1212, 2004 | 102 | 2004 |
| Impact of boosted antiretroviral therapy on the pharmacokinetics and efficacy of clopidogrel and prasugrel active metabolites N Marsousi, Y Daali, P Fontana, JL Reny, V Ancrenaz-Sirot, A Calmy, ... Clinical pharmacokinetics 57, 1347-1354, 2018 | 100 | 2018 |
| On‐line desorption of dried blood spots coupled to hydrophilic interaction/reversed‐phase LC/MS/MS system for the simultaneous analysis of drugs and their polar metabolites A Thomas, J Déglon, T Steimer, P Mangin, Y Daali, C Staub Journal of Separation Science 33 (6‐7), 873-879, 2010 | 100 | 2010 |
| Dynamics of active pharmaceutical ingredients loads in a Swiss university hospital wastewaters and prediction of the related environmental risk for the aquatic ecosystems S Daouk, N Chèvre, N Vernaz, C Widmer, Y Daali, S Fleury-Souverain Science of The Total Environment 547, 244-253, 2016 | 89 | 2016 |
| Usefulness of PBPK modeling in incorporation of clinical conditions in personalized medicine N Marsousi, JA Desmeules, S Rudaz, Y Daali Journal of pharmaceutical sciences 106 (9), 2380-2391, 2017 | 81 | 2017 |
