Decreased consumption of branched-chain amino acids improves metabolic health L Fontana, NE Cummings, SIA Apelo, JC Neuman, I Kasza, BA Schmidt, ... Cell reports 16 (2), 520-530, 2016 | 459 | 2016 |
Overview of affinity tags for protein purification ME Kimple, AL Brill, RL Pasker Current protocols in protein science 73 (1), 9.9. 1-9.9. 23, 2013 | 456 | 2013 |
Restoration of metabolic health by decreased consumption of branched‐chain amino acids NE Cummings, EM Williams, I Kasza, EN Konon, MD Schaid, BA Schmidt, ... The Journal of physiology 596 (4), 623-645, 2018 | 331 | 2018 |
Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits RJ Kimple, ME Kimple, L Betts, J Sondek, DP Siderovski Nature 416 (6883), 878-881, 2002 | 314 | 2002 |
Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system SI Arriola Apelo, JC Neuman, EL Baar, FA Syed, NE Cummings, HK Brar, ... Aging cell 15 (1), 28-38, 2016 | 187 | 2016 |
Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic β cells DJ Pagliarini, SE Wiley, ME Kimple, JR Dixon, P Kelly, CA Worby, ... Molecular cell 19 (2), 197-207, 2005 | 171 | 2005 |
Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose-and hormone-stimulated insulin secretion ME Kimple, MP Keller, MR Rabaglia, RL Pasker, JC Neuman, ... Diabetes 62 (6), 1904-1912, 2013 | 129 | 2013 |
Overview of affinity tags for protein purification ME Kimple, J Sondek Current protocols in protein science 36 (1), 9.9. 1-9.9. 19, 2004 | 112 | 2004 |
Phenotypic characterization of MIP-CreERT1Lphi mice with transgene-driven islet expression of human growth hormone D Oropeza, N Jouvet, L Budry, JE Campbell, K Bouyakdan, J Lacombe, ... Diabetes 64 (11), 3798-3807, 2015 | 97 | 2015 |
Short-term methionine deprivation improves metabolic health via sexually dimorphic, mTORC1-independent mechanisms D Yu, SE Yang, BR Miller, JA Wisinski, DS Sherman, JA Brinkman, ... The FASEB Journal 32 (6), 3471, 2018 | 89 | 2018 |
Functional relevance of the disulfide‐linked complex of the N‐terminal PDZ domain of InaD with NorpA ME Kimple, DP Siderovski, J Sondek The EMBO Journal, 2001 | 76 | 2001 |
Pancreatic β-cells from mice offset age-associated mitochondrial deficiency with reduced KATP channel activity T Gregg, C Poudel, BA Schmidt, RS Dhillon, SM Sdao, NA Truchan, ... Diabetes 65 (9), 2700-2710, 2016 | 75 | 2016 |
Inhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes ME Kimple, JC Neuman, AK Linnemann, PJ Casey Experimental & molecular medicine 46 (6), e102-e102, 2014 | 69 | 2014 |
Glucagon-like peptide-1 regulates cholecystokinin production in β-cells to protect from apoptosis AK Linnemann, JC Neuman, TJ Battiola, JA Wisinski, ME Kimple, ... Molecular endocrinology 29 (7), 978-987, 2015 | 65 | 2015 |
A method for mouse pancreatic islet isolation and intracellular cAMP determination JC Neuman, NA Truchan, JW Joseph, ME Kimple Journal of visualized experiments: JoVE, 50374, 2014 | 65 | 2014 |
Opposing effects of prostaglandin E2 receptors EP3 and EP4 on mouse and human β-cell survival and proliferation BA Carboneau, JA Allan, SE Townsend, ME Kimple, RM Breyer, ... Molecular metabolism 6 (6), 548-559, 2017 | 55 | 2017 |
Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line KA Krautkramer, AK Linnemann, DA Fontaine, AL Whillock, TW Harris, ... American Journal of Physiology-Endocrinology and Metabolism 305 (5), E600-E610, 2013 | 54 | 2013 |
Gαz negatively regulates insulin secretion and glucose clearance ME Kimple, JW Joseph, CL Bailey, PT Fueger, IA Hendry, CB Newgard, ... Journal of Biological Chemistry 283 (8), 4560-4567, 2008 | 52 | 2008 |
Enriching islet phospholipids with eicosapentaenoic acid reduces prostaglandin E2 signaling and enhances diabetic β-cell function JC Neuman, MD Schaid, AL Brill, RJ Fenske, CR Kibbe, DA Fontaine, ... Diabetes 66 (6), 1572-1585, 2017 | 50 | 2017 |
A role for Gz in pancreatic islet β-cell biology ME Kimple, AB Nixon, P Kelly, CL Bailey, KH Young, TA Fields, PJ Casey Journal of Biological Chemistry 280 (36), 31708-31713, 2005 | 50 | 2005 |