A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans AK Walker, RL Jacobs, JL Watts, V Rottiers, K Jiang, DM Finnegan, ... Cell 147 (4), 840-852, 2011 | 482 | 2011 |
An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis F Yang, BW Vought, JS Satterlee, AK Walker, ZY Jim Sun, JL Watts, ... Nature 442 (7103), 700-704, 2006 | 463 | 2006 |
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP AK Walker, F Yang, K Jiang, JY Ji, JL Watts, A Purushotham, O Boss, ... Genes & development 24 (13), 1403-1417, 2010 | 405 | 2010 |
CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo EY Shim, AK Walker, Y Shi, TK Blackwell Genes & development 16 (16), 2135-2146, 2002 | 252 | 2002 |
WormCat: An Online Tool for Annotation and Visualization of Caenorhabditis elegans Genome-Scale Data AD Holdorf, DP Higgins, AC Hart, PR Boag, GJ Pazour, AJM Walhout, ... Genetics 214 (2), 279-294, 2020 | 171 | 2020 |
s-Adenosylmethionine levels govern innate immunity through distinct methylation-dependent pathways W Ding, LJ Smulan, NS Hou, S Taubert, JL Watts, AK Walker Cell metabolism 22 (4), 633-645, 2015 | 140 | 2015 |
Conserved genes act as modifiers of invertebrate SMN loss of function defects M Dimitriadi, JN Sleigh, A Walker, HC Chang, A Sen, G Kalloo, J Harris, ... PLoS genetics 6 (10), e1001172, 2010 | 121 | 2010 |
A conserved transcription motif suggesting functional parallels between Caenorhabditis elegans SKN-1 and Cap'n'Collar-related basic leucine zipper proteins AK Walker, R See, C Batchelder, T Kophengnavong, JT Gronniger, Y Shi, ... Journal of Biological Chemistry 275 (29), 22166-22171, 2000 | 98 | 2000 |
Hormone‐regulated v‐rel estrogen receptor fusion protein: reversible induction of cell transformation and cellular gene expression. G Boehmelt, A Walker, N Kabrun, G Mellitzer, H Beug, M Zenke, ... The EMBO Journal 11 (12), 4641-4652, 1992 | 87 | 1992 |
Distinct requirements for C. elegans TAFIIs in early embryonic transcription AK Walker, JH Rothman, Y Shi, TK Blackwell The EMBO journal, 2001 | 60 | 2001 |
Cholesterol-independent SREBP-1 maturation is linked to ARF1 inactivation LJ Smulan, W Ding, E Freinkman, S Gujja, YJK Edwards, AK Walker Cell reports 16 (1), 9-18, 2016 | 58 | 2016 |
Transcription reactivation steps stimulated by oocyte maturation in C. elegans AK Walker, PR Boag, TK Blackwell Developmental biology 304 (1), 382-393, 2007 | 53 | 2007 |
The Caenorhabditis elegans ortholog of TRAP240, CeTRAP240/let-19, selectively modulates gene expression and is essential for embryogenesis JC Wang, A Walker, TK Blackwell, KR Yamamoto Journal of biological chemistry 279 (28), 29270-29277, 2004 | 40 | 2004 |
Stress-responsive and metabolic gene regulation are altered in low S-adenosylmethionine W Ding, DP Higgins, DK Yadav, AA Godbole, R Pukkila-Worley, ... PLoS Genetics 14 (11), e1007812, 2018 | 34 | 2018 |
1-Carbon cycle metabolites methylate their way to fatty liver AK Walker Trends in Endocrinology & Metabolism 28 (1), 63-72, 2017 | 33 | 2017 |
Defining characteristics and conservation of poorly annotated genes in Caenorhabditis elegans using WormCat 2.0 DP Higgins, CM Weisman, DS Lui, FA D’Agostino, AK Walker Genetics 221 (4), iyac085, 2022 | 31 | 2022 |
An extensive requirement for transcription factor IID-specific TAF-1 in Caenorhabditis elegans embryonic transcription AK Walker, Y Shi, TK Blackwell Journal of Biological Chemistry 279 (15), 15339-15347, 2004 | 30 | 2004 |
Transcription mechanisms TK Blackwell, AK Walker WormBook: The Online Review of C. elegans Biology [Internet], 2006 | 29 | 2006 |
SREBPs: regulators of cholesterol/lipids as therapeutic targets in metabolic disorders, cancers and viral diseases AK Walker, AM Näär Clinical Lipidology and Metabolic Disorders 7 (1), 2012 | 28 | 2012 |
Broad requirement for the mediator subunit RGR-1 for transcription in the Caenorhabditis elegans embryo EY Shim, AK Walker, TK Blackwell Journal of Biological Chemistry 277 (34), 30413-30416, 2002 | 28 | 2002 |