| CRISPR-Cas9 in vivo gene editing for transthyretin amyloidosis JD Gillmore, E Gane, J Taubel, J Kao, M Fontana, ML Maitland, J Seitzer, ... New England Journal of Medicine 385 (6), 493-502, 2021 | 1341 | 2021 |
| Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium F Dieterle, F Sistare, F Goodsaid, M Papaluca, JS Ozer, CP Webb, W Baer, ... Nature biotechnology 28 (5), 455-462, 2010 | 493 | 2010 |
| Collagen gel contraction assay P Ngo, P Ramalingam, JA Phillips, GT Furuta Cell-Cell Interactions: Methods and Protocols, 103-109, 2006 | 219 | 2006 |
| Towards consensus practices to qualify safety biomarkers for use in early drug development FD Sistare, F Dieterle, S Troth, DJ Holder, D Gerhold, ... Nature biotechnology 28 (5), 446-454, 2010 | 139 | 2010 |
| Total-Body Irradiation of Postpubertal Mice with 137Cs Acutely Compromises the Microarchitecture of Cancellous Bone and Increases Osteoclasts H Kondo, ND Searby, R Mojarrab, J Phillips, J Alwood, K Yumoto, ... Radiation research 171 (3), 283-289, 2009 | 131 | 2009 |
| Microphysiological systems for ADME-related applications: current status and recommendations for system development and characterization S Fowler, WLK Chen, DB Duignan, A Gupta, N Hariparsad, JR Kenny, ... Lab on a Chip 20 (3), 446-467, 2020 | 91 | 2020 |
| Navigating tissue chips from development to dissemination: A pharmaceutical industry perspective L Ewart, K Fabre, A Chakilam, Y Dragan, DB Duignan, J Eswaraka, J Gan, ... Experimental Biology and Medicine 242 (16), 1579-1585, 2017 | 89 | 2017 |
| Role for β1 integrins in cortical osteocytes during acute musculoskeletal disuse JA Phillips, EAC Almeida, EL Hill, JI Aguirre, MF Rivera, I Nachbandi, ... Matrix Biology 27 (7), 609-618, 2008 | 64 | 2008 |
| A pharmaceutical industry perspective on microphysiological kidney systems for evaluation of safety for new therapies JA Phillips, TSP Grandhi, M Davis, JC Gautier, N Hariparsad, D Keller, ... Lab on a Chip 20 (3), 468-476, 2020 | 42 | 2020 |
| Fibroblasts regulate contractile force independent of MMP activity in 3D-collagen JA Phillips, CA Vacanti, LJ Bonassar Biochemical and biophysical research communications 312 (3), 725-732, 2003 | 42 | 2003 |
| Rat urinary osteopontin and neutrophil gelatinase-associated lipocalin improve certainty of detecting drug-induced kidney injury JA Phillips, DJ Holder, D Ennulat, JC Gautier, JM Sauer, Y Yang, ... Toxicological Sciences 151 (2), 214-223, 2016 | 40 | 2016 |
| Matrix metalloproteinase activity synergizes with α2β1 integrins to enhance collagen remodeling JA Phillips, LJ Bonassar Experimental Cell Research 310 (1), 79-87, 2005 | 34 | 2005 |
| Net reclassification index and integrated discrimination index are not appropriate for testing whether a biomarker improves predictive performance PM Burch, WE Glaab, DJ Holder, JA Phillips, JM Sauer, EG Walker Toxicological Sciences 156 (1), 11-13, 2017 | 31 | 2017 |
| Crispr-Cas9 JD Gillmore, E Gane, J Taubel, J Kao, M Fontana, ML Maitland, J Seitzer, ... vivo, 2021 | 29 | 2021 |
| A predominant oxidative renal metabolite of empagliflozin in male mice is cytotoxic in mouse renal tubular cells but not genotoxic JD Smith, Z Huang, PA Escobar, P Foppiano, H Maw, W Loging, H Yu, ... International Journal of Toxicology 36 (6), 440-448, 2017 | 14 | 2017 |
| Development of the gecko (Pachydactylus turneri) animal model during Foton M-2 to study comparative effects of microgravity in terrestrial and aquatic organisms EA Almeida, C Roden, JA Phillips, RK Globus, N Searby, W Vercoutere, ... Journal of Gravitational Physiology, Volume 13, No. 1, 2006 | 13 | 2006 |
| Assessment of Inhibin B as a Biomarker of Testicular Injury Following Administration of Carbendazim, Cetrorelix, or 1, 2‐Dibromo‐3‐Chloropropane in Wistar Han Rats JS Moffit, LS Her, AM Mineo, BL Knight, JA Phillips, MS Thibodeau Birth Defects Research Part B: Developmental and Reproductive Toxicology 98 …, 2013 | 8 | 2013 |
| Mode of action and human relevance assessment of male CD‐1 mouse renal adenocarcinoma associated with lifetime exposure to empagliflozin JA Phillips, ME Taub, MS Bogdanffy, J Yuan, B Knight, JD Smith, WW Ku Journal of Applied Toxicology 42 (10), 1570-1584, 2022 | 7 | 2022 |
| Discovery and optimization of pyrazole amides as inhibitors of ELOVL1 JH Come, TJ Senter, MP Clark, JJ Court, Z Gale-Day, W Gu, E Krueger, ... Journal of medicinal chemistry 64 (24), 17753-17776, 2021 | 7 | 2021 |
| Pathogenesis of renal injury and gene expression changes in the male CD-1 mouse associated with exposure to Empagliflozin B Knight, J Yuan, S Koegler, P Pande, J Hall, JD Hill, SE Hart, JA Phillips, ... Toxicologic Pathology 46 (6), 671-682, 2018 | 7 | 2018 |
Jinping GanVerified email at alum.mit.edu
