Dynamic properties of the Sulfolobus CRISPR/Cas and CRISPR/Cmr systems when challenged with vector‐borne viral and plasmid genes and protospacers S Gudbergsdottir, L Deng, Z Chen, JVK Jensen, LR Jensen, Q She, ... Molecular microbiology 79 (1), 35-49, 2011 | 341 | 2011 |
A novel interference mechanism by a type IIIB CRISPR‐Cmr module in Sulfolobus L Deng, RA Garrett, SA Shah, X Peng, Q She Molecular microbiology 87 (5), 1088-1099, 2013 | 301 | 2013 |
Unmarked gene deletion and host–vector system for the hyperthermophilic crenarchaeon Sulfolobus islandicus L Deng, H Zhu, Z Chen, YX Liang, Q She Extremophiles 13, 735-746, 2009 | 198 | 2009 |
Fecal filtrate transplantation protects against necrotizing enterocolitis A Brunse, L Deng, X Pan, Y Hui, JL Castro-Mejía, W Kot, DN Nguyen, ... The ISME journal 16 (3), 686-694, 2022 | 109 | 2022 |
A synthetic arabinose-inducible promoter confers high levels of recombinant protein expression in hyperthermophilic archaeon Sulfolobus islandicus N Peng, L Deng, Y Mei, D Jiang, Y Hu, M Awayez, Y Liang, Q She Applied and environmental microbiology 78 (16), 5630-5637, 2012 | 102 | 2012 |
A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction W Han, Y Li, L Deng, M Feng, W Peng, S Hallstrøm, J Zhang, N Peng, ... Nucleic acids research 45 (4), 1983-1993, 2017 | 93 | 2017 |
Bacteriophage-mediated manipulation of the gut microbiome–promises and presents limitations TS Rasmussen, AK Koefoed, RR Jakobsen, L Deng, JL Castro-Mejía, ... FEMS Microbiology Reviews 44 (4), 507-521, 2020 | 92 | 2020 |
Genome binning of viral entities from bulk metagenomics data J Johansen, DR Plichta, JN Nissen, ML Jespersen, SA Shah, L Deng, ... Nature communications 13 (1), 965, 2022 | 84 | 2022 |
Modulation of CRISPR locus transcription by the repeat-binding protein Cbp1 in Sulfolobus L Deng, CS Kenchappa, X Peng, Q She, RA Garrett Nucleic acids research 40 (6), 2470-2480, 2012 | 81 | 2012 |
Virulent coliphages in 1-year-old children fecal samples are fewer, but more infectious than temperate coliphages A Mathieu, M Dion, L Deng, D Tremblay, E Moncaut, SA Shah, J Stokholm, ... Nature Communications 11 (1), 378, 2020 | 77 | 2020 |
Expanding known viral diversity in the healthy infant gut SA Shah, L Deng, J Thorsen, AG Pedersen, MB Dion, JL Castro-Mejía, ... Nature microbiology 8 (5), 986-998, 2023 | 76 | 2023 |
Revealing the essentiality of multiple archaeal pcna genes using a mutant propagation assay based on an improved knockout method C Zhang, L Guo, L Deng, Y Wu, Y Liang, L Huang, Q She Microbiology 156 (11), 3386-3397, 2010 | 68 | 2010 |
CRISPR-based immune systems of the Sulfolobales: complexity and diversity RA Garrett, SA Shah, G Vestergaard, L Deng, S Gudbergsdottir, ... Biochemical Society Transactions 39 (1), 51-57, 2011 | 65 | 2011 |
Genetic analyses in the hyperthermophilic archaeon Sulfolobus islandicus Q She, C Zhang, L Deng, N Peng, Z Chen, YX Liang Biochemical Society Transactions 37 (1), 92-96, 2009 | 65 | 2009 |
High-Level Expression of an Aspergillus niger Endo--1,4-Glucanase in Pichia pastoris Through Gene Codon Optimization and Synthesis S Zhao, J Huang, C Zhang, L Deng, N Hu, Y Liang Journal of microbiology and biotechnology 20 (3), 467-473, 2010 | 59 | 2010 |
CRISPR-Cas adaptive immune systems of the Sulfolobales: unravelling their complexity and diversity RA Garrett, SA Shah, S Erdmann, G Liu, M Mousaei, C León-Sobrino, ... Life 5 (1), 783-817, 2015 | 57 | 2015 |
A protocol for extraction of infective viromes suitable for metagenomics sequencing from low volume fecal samples L Deng, R Silins, JL Castro-Mejía, W Kot, L Jessen, J Thorsen, S Shah, ... Viruses 11 (7), 667, 2019 | 50 | 2019 |
Characterization of the vaginal DNA virome in health and dysbiosis RR Jakobsen, T Haahr, P Humaidan, JS Jensen, WP Kot, JL Castro-Mejia, ... Viruses 12 (10), 1143, 2020 | 45 | 2020 |
Novel insights into gene regulation of the rudivirus SIRV2 infecting Sulfolobus cells E Okutan, L Deng, S Mirlashari, K Uldahl, M Halim, C Liu, RA Garrett, ... RNA biology 10 (5), 875-885, 2013 | 45 | 2013 |
A novel single-tailed fusiform Sulfolobus virus STSV2 infecting model Sulfolobus species S Erdmann, B Chen, X Huang, L Deng, C Liu, SA Shah, ... Extremophiles 18, 51-60, 2014 | 43 | 2014 |