The enolase superfamily: a general strategy for enzyme-catalyzed abstraction of the α-protons of carboxylic acids PC Babbitt, MS Hasson, JE Wedekind, DRJ Palmer, WC Barrett, GH Reed, ... Biochemistry 35 (51), 16489-16501, 1996 | 432 | 1996 |
Unexpected divergence of enzyme function and sequence:“N-acylamino acid racemase” is o-succinylbenzoate synthase DRJ Palmer, JB Garrett, V Sharma, R Meganathan, PC Babbitt, JA Gerlt Biochemistry 38 (14), 4252-4258, 1999 | 166 | 1999 |
Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli BK Hubbard, M Koch, DRJ Palmer, PC Babbitt, JA Gerlt Biochemistry 37 (41), 14369-14375, 1998 | 108 | 1998 |
Succinylphosphonate esters are competitive inhibitors of MenD that show active-site discrimination between homologous α-ketoglutarate-decarboxylating enzymes M Fang, RD Toogood, A Macova, K Ho, SG Franzblau, MR McNeil, ... Biochemistry 49 (12), 2672-2679, 2010 | 60 | 2010 |
Evolution of enzymatic activities in the enolase superfamily: crystallographic and mutagenesis studies of the reaction catalyzed by D-glucarate dehydratase from Escherichia coli AM Gulick, BK Hubbard, JA Gerlt, I Rayment Biochemistry 39 (16), 4590-4602, 2000 | 59 | 2000 |
The Lesser “Burden Borne” by o-Succinylbenzoate Synthase: An “Easy” Reaction Involving a Carboxylate Carbon Acid EA Taylor, DRJ Palmer, JA Gerlt Journal of the American Chemical Society 123 (24), 5824-5825, 2001 | 49 | 2001 |
A Previously Unrecognized Kanosamine Biosynthesis Pathway in Bacillus subtilis ND Vetter, DM Langill, S Anjum, J Boisvert-Martel, RC Jagdhane, ... Journal of the American Chemical Society 135 (16), 5970-5973, 2013 | 48 | 2013 |
Evolution of Enzymatic Activities in the Enolase Superfamily: Crystal Structure of (D)-Glucarate Dehydratase from Pseudomonas putida, AM Gulick, DRJ Palmer, PC Babbitt, JA Gerlt, I Rayment Biochemistry 37 (41), 14358-14368, 1998 | 46 | 1998 |
Methanogen Homoaconitase Catalyzes Both Hydrolyase Reactions in Coenzyme B Biosynthesis∗ RM Drevland, Y Jia, DRJ Palmer, DE Graham Journal of Biological Chemistry 283 (43), 28888-28896, 2008 | 44 | 2008 |
Steady-State Kinetics and Molecular Evolution of Escherichia coli MenD [(1R,6R)-2-Succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate Synthase], an … M Bhasin, JL Billinsky, DRJ Palmer Biochemistry 42 (46), 13496-13504, 2003 | 41 | 2003 |
Biomimetic Design Results in a Potent Allosteric Inhibitor of Dihydrodipicolinate Synthase from Campylobacter jejuni YV Skovpen, CJT Conly, DAR Sanders, DRJ Palmer Journal of the American Chemical Society 138 (6), 2014-2020, 2016 | 34 | 2016 |
Using Substrate Analogues To Probe the Kinetic Mechanism and Active Site of Escherichia coli MenD M Fang, A Macova, KL Hanson, J Kos, DRJ Palmer Biochemistry 50 (40), 8712-8721, 2011 | 32 | 2011 |
Kinetics and product analysis of the reaction catalysed by recombinant homoaconitase from Thermus thermophilus Y Jia, T Tomita, K Yamauchi, M Nishiyama, DRJ Palmer Biochemical Journal 396 (3), 479-485, 2006 | 31 | 2006 |
Synthesis and antifungal properties of compounds which target the α-aminoadipate pathway DRJ Palmer, H Balogh, G Ma, X Zhou, M Marko, SGW Kaminskyj Die Pharmazie-An International Journal of Pharmaceutical Sciences 59 (2), 93-98, 2004 | 29 | 2004 |
The structure of NtdA, a sugar aminotransferase involved in the kanosamine biosynthetic pathway in Bacillus subtilis, reveals a new subclass of aminotransferases KE van Straaten, JB Ko, R Jagdhane, S Anjum, DRJ Palmer, ... Journal of Biological Chemistry 288 (47), 34121-34130, 2013 | 28 | 2013 |
Evolution of enzymatic activities: multiple pathways for generating and partitioning a common enolic intermediate by glucarate dehydratase from Pseudomonas putida DRJ Palmer, JA Gerlt Journal of the American Chemical Society 118 (42), 10323-10324, 1996 | 28 | 1996 |
Dihydrodipicolinate Synthase from Campylobacter jejuni: Kinetic Mechanism of Cooperative Allosteric Inhibition and Inhibitor-Induced Substrate Cooperativity YV Skovpen, DRJ Palmer Biochemistry 52 (32), 5454-5462, 2013 | 27 | 2013 |
Kinetic evaluation of glucose 1-phosphate analogues with a thymidylyltransferase using a continuous coupled enzyme assay SM Forget, A Jee, DA Smithen, R Jagdhane, S Anjum, SA Beaton, ... Organic & Biomolecular Chemistry 13 (3), 866-875, 2015 | 25 | 2015 |
Evolution of enzymatic activities in the enolase superfamily: Partitioning of reactive intermediates by (D)-glucarate dehydratase from Pseudomonas putida DRJ Palmer, BK Hubbard, JA Gerlt Biochemistry 37 (41), 14350-14357, 1998 | 25 | 1998 |
Evidence of allosteric enzyme regulation via changes in conformational dynamics: a hydrogen/deuterium exchange investigation of dihydrodipicolinate synthase MA Sowole, S Simpson, YV Skovpen, DRJ Palmer, L Konermann Biochemistry 55 (38), 5413-5422, 2016 | 24 | 2016 |