De novo DNA synthesis using polymerase-nucleotide conjugates S Palluk, DH Arlow, T De Rond, S Barthel, JS Kang, R Bector, ... Nature biotechnology 36 (7), 645-650, 2018 | 320 | 2018 |
Viscous control of cellular respiration by membrane lipid composition I Budin, T de Rond, Y Chen, LJG Chan, CJ Petzold, JD Keasling Science 362 (6419), 1186-1189, 2018 | 205 | 2018 |
Mining genomes to illuminate the specialized chemistry of life MH Medema, T de Rond, BS Moore Nature Reviews Genetics 22 (9), 553-571, 2021 | 195 | 2021 |
Artificial intelligence for natural product drug discovery MW Mullowney, KR Duncan, SS Elsayed, N Garg, JJJ van der Hooft, ... Nature Reviews Drug Discovery 22 (11), 895-916, 2023 | 146 | 2023 |
A community resource for paired genomic and metabolomic data mining MA Schorn, S Verhoeven, L Ridder, F Huber, DD Acharya, AA Aksenov, ... Nature Chemical Biology 17 (4), 363-368, 2021 | 118 | 2021 |
Engineering a Polyketide Synthase for In Vitro Production of Adipic Acid A Hagen, S Poust, T Rond, JL Fortman, L Katz, CJ Petzold, JD Keasling ACS synthetic biology 5 (1), 21-27, 2016 | 105 | 2016 |
Ancient plant-like terpene biosynthesis in corals I Burkhardt, T de Rond, PYT Chen, BS Moore Nature chemical biology 18 (6), 664-669, 2022 | 68 | 2022 |
High throughput screening of enzyme activity with mass spectrometry imaging T de Rond, M Danielewicz, T Northen Current Opinion in Biotechnology 31, 1-9, 2015 | 68 | 2015 |
High-titer production of lathyrane diterpenoids from sugar by engineered Saccharomyces cerevisiae J Wong, T de Rond, L d’Espaux, C van der Horst, I Dev, L Rios-Solis, ... Metabolic engineering 45, 142-148, 2018 | 66 | 2018 |
Lipid engineering reveals regulatory roles for membrane fluidity in yeast flocculation and oxygen-limited growth D Degreif, T de Rond, A Bertl, JD Keasling, I Budin Metabolic engineering 41, 46-56, 2017 | 61 | 2017 |
A high‐throughput mass spectrometric enzyme activity assay enabling the discovery of cytochrome P450 biocatalysts T de Rond, J Gao, A Zargar, M de Raad, J Cunha, TR Northen, ... Angewandte Chemie 131 (30), 10220-10225, 2019 | 45 | 2019 |
Oxidative cyclization of prodigiosin by an alkylglycerol monooxygenase-like enzyme T de Rond, P Stow, I Eigl, RE Johnson, LJG Chan, G Goyal, EEK Baidoo, ... Nature chemical biology 13 (11), 1155-1157, 2017 | 33 | 2017 |
In Vitro Analysis of Carboxyacyl Substrate Tolerance in the Loading and First Extension Modules of Borrelidin Polyketide Synthase A Hagen, S Poust, T de Rond, S Yuzawa, L Katz, PD Adams, CJ Petzold, ... Biochemistry 53 (38), 5975-5977, 2014 | 31 | 2014 |
Terpene biosynthesis in marine sponge animals K Wilson, T de Rond, I Burkhardt, TS Steele, RJB Schäfer, S Podell, ... Proceedings of the National Academy of Sciences 120 (9), e2220934120, 2023 | 29 | 2023 |
Mevalonate pathway promiscuity enables noncanonical terpene production CB Eiben, T De Rond, C Bloszies, J Gin, J Chiniquy, EEK Baidoo, ... ACS synthetic biology 8 (10), 2238-2247, 2019 | 26 | 2019 |
Probing the Flexibility of an Iterative Modular Polyketide Synthase with Non-Native Substrates in Vitro SC Curran, A Hagen, S Poust, LJG Chan, BM Garabedian, T de Rond, ... ACS chemical biology 13 (8), 2261-2268, 2018 | 24 | 2018 |
Synthesis of cycloprodigiosin identifies the natural isolate as a scalemic mixture RE Johnson, T de Rond, VNG Lindsay, JD Keasling, R Sarpong Organic letters 17 (14), 3474-3477, 2015 | 24 | 2015 |
OpenMSI Arrayed Analysis Toolkit: analyzing spatially defined samples using mass spectrometry imaging M de Raad, T de Rond, O Rübel, JD Keasling, TR Northen, BP Bowen Analytical chemistry 89 (11), 5818-5823, 2017 | 23 | 2017 |
Versatile synthesis of probes for high-throughput enzyme activity screening T de Rond, P Peralta-Yahya, X Cheng, TR Northen, JD Keasling Analytical and bioanalytical chemistry 405, 4969-4973, 2013 | 16 | 2013 |
Co-occurrence of enzyme domains guides the discovery of an oxazolone synthetase T de Rond, JE Asay, BS Moore Nature chemical biology 17 (7), 794-799, 2021 | 15 | 2021 |