| A dual role for autophagy in a murine model of lung cancer S Rao, L Tortola, T Perlot, G Wirnsberger, M Novatchkova, R Nitsch, ... Nature communications 5 (1), 3056, 2014 | 457 | 2014 |
| Psoriasiform dermatitis is driven by IL-36–mediated DC-keratinocyte crosstalk L Tortola, E Rosenwald, B Abel, H Blumberg, M Schäfer, AJ Coyle, ... The Journal of clinical investigation 122 (11), 3965-3976, 2012 | 457 | 2012 |
| The metabolite BH4 controls T cell proliferation in autoimmunity and cancer SJF Cronin, C Seehus, A Weidinger, S Talbot, S Reissig, M Seifert, ... Nature 563 (7732), 564-568, 2018 | 240 | 2018 |
| RANKL/RANK control Brca1 mutation-driven mammary tumors V Sigl, K Owusu-Boaitey, PA Joshi, A Kavirayani, G Wirnsberger, ... Cell research 26 (7), 761-774, 2016 | 171 | 2016 |
| The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation J Muri, S Heer, M Matsushita, L Pohlmeier, L Tortola, T Fuhrer, M Conrad, ... Nature communications 9 (1), 1851, 2018 | 123 | 2018 |
| Inhibition of CBLB protects from lethal Candida albicans sepsis G Wirnsberger, F Zwolanek, T Asaoka, I Kozieradzki, L Tortola, ... Nature medicine 22 (8), 915-923, 2016 | 106 | 2016 |
| Apelin inhibition prevents resistance and metastasis associated with anti‐angiogenic therapy I Uribesalgo, D Hoffmann, Y Zhang, A Kavirayani, J Lazovic, J Berta, ... EMBO molecular medicine 11 (8), e9266, 2019 | 105 | 2019 |
| The kinase activity of Rip2 determines its stability and consequently Nod1-and Nod2-mediated immune responses C Nembrini, J Kisielow, AT Shamshiev, L Tortola, AJ Coyle, M Kopf, ... Journal of Biological Chemistry 284 (29), 19183-19188, 2009 | 104 | 2009 |
| Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self‐renewal and identity R Rauschmeier, C Gustafsson, A Reinhardt, N A‐Gonzalez, L Tortola, ... The EMBO journal 38 (19), e101233, 2019 | 87 | 2019 |
| The tumor suppressor Hace1 is a critical regulator of TNFR1-mediated cell fate L Tortola, R Nitsch, MJM Bertrand, M Kogler, Y Redouane, I Kozieradzki, ... Cell reports 15 (7), 1481-1492, 2016 | 69 | 2016 |
| Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense G Wirnsberger, F Zwolanek, J Stadlmann, L Tortola, SW Liu, T Perlot, ... Nature genetics 46 (9), 1028-1033, 2014 | 64 | 2014 |
| High-dimensional T helper cell profiling reveals a broad diversity of stably committed effector states and uncovers interlineage relationships L Tortola, A Jacobs, L Pohlmeier, FJ Obermair, F Ampenberger, ... Immunity 53 (3), 597-613. e6, 2020 | 58 | 2020 |
| IL-21 promotes allergic airway inflammation by driving apoptosis of FoxP3+ regulatory T cells L Tortola, H Pawelski, SS Sonar, F Ampenberger, M Kurrer, M Kopf Journal of Allergy and Clinical Immunology 143 (6), 2178-2189. e5, 2019 | 45 | 2019 |
| RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer S Rao, V Sigl, RA Wimmer, M Novatchkova, A Jais, G Wagner, ... Genes & Development 31 (20), 2099-2112, 2017 | 40 | 2017 |
| Evidence for the divergence of innate and adaptive T-cell precursors before commitment to the αβ and γδ lineages J Kisielow, L Tortola, J Weber, K Karjalainen, M Kopf Blood, The Journal of the American Society of Hematology 118 (25), 6591-6600, 2011 | 36 | 2011 |
| Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing N Frey, L Tortola, D Egli, S Janjuha, T Rothgangl, KF Marquart, ... Nature communications 13 (1), 1804, 2022 | 35 | 2022 |
| IL-21 induces death of marginal zone B cells during chronic inflammation L Tortola, K Yadava, MF Bachmann, C Müller, J Kisielow, M Kopf Blood, The Journal of the American Society of Hematology 116 (24), 5200-5207, 2010 | 32 | 2010 |
| Adult T-cells impair neonatal cardiac regeneration T Dolejsi, M Delgobo, T Schuetz, L Tortola, KG Heinze, U Hofmann, ... European Heart Journal 43 (28), 2698-2709, 2022 | 31 | 2022 |
| Cyclopentenone prostaglandins and structurally related oxidized lipid species instigate and share distinct pro-and anti-inflammatory pathways J Muri, Q Feng, H Wolleb, A Shamshiev, C Ebner, L Tortola, P Broz, ... Cell reports 30 (13), 4399-4417. e7, 2020 | 28 | 2020 |
| HACE1 prevents lung carcinogenesis via inhibition of RAC-family GTPases M Kogler, L Tortola, GL Negri, A Leopoldi, AM El-Naggar, S Mereiter, ... Cancer research 80 (14), 3009-3022, 2020 | 25 | 2020 |
